502219
Dabsyl chloride
Synonym(s):
4-(Dimethylamino)azobenzene-4′-sulfonyl chloride, 4-(4-Dimethylaminophenylazo)benzenesulfonyl chloride, DABS-Cl, Dabsyl chloride
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Linear Formula:
(CH3)2NC6H4N=NC6H4SO2Cl
CAS Number:
Molecular Weight:
323.80
EC Number:
260-235-1
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
3064095
MDL number:
grade
derivatization grade ((HPLC))
form
solid
packaging
pkg of 500 mg
mp
185 °C (dec.) (lit.)
storage temp.
room temp
SMILES string
CN(C)c1ccc(cc1)\N=N\c2ccc(cc2)S(Cl)(=O)=O
InChI
1S/C14H14ClN3O2S/c1-18(2)13-7-3-11(4-8-13)16-17-12-5-9-14(10-6-12)21(15,19)20/h3-10H,1-2H3/b17-16+
InChI key
VTVWTPGLLAELLI-WUKNDPDISA-N
General description
Dabsyl chloride (4-dimethylaminoazobenzene-4′-sulfonyl chloride) is a chromophoric labeling reagent used in HPLC for derivatizing amino acids. It reacts freely with all amino acids in order to form dabsyl amino acids, which are photostable and can be seen on a thin-layer chromatographic plate.
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Chromophoric labeling of amino acids with 4-dimethylaminoazobenzene-4'-sulfonyl chloride.
J K Lin and J Y Chang.
Analytical Chemistry, 47 (9), 1634-1638 (1975)
A Zaramella et al.
Journal of combinatorial chemistry, 3(5), 410-420 (2001-09-11)
The presence of dansyl or dabsyl chromogenic moieties in a solid-phase analytical construct, an assembly of linkers/spacers/sensitizers for improving analytical characterization, allows the accurate estimation of products from solid-phase synthesis by UV detection during liquid chromatography-mass spectrometry analysis in the
P A de Witte et al.
Journal of pharmaceutical and biomedical analysis, 14(8-10), 1063-1067 (1996-06-01)
A method has been developed for the analysis of phosphoserine, phosphothreonine and phosphotyrosine in 32P-phosphoprotein hydrolysates. The hydrolysates are treated with dabsyl reagent (28.8 mM) for 10 min at 70 degrees C. After a clean-up using a disposable C18 column