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Showing 31-60 of 273 results for "B2629" within Papers
Sébastien Bergeron et al.
Analytical and bioanalytical chemistry, 407(28), 8451-8462 (2015-09-09)
Microarrays allow the miniaturization and multiplexing of biological assays while only requiring minute amounts of samples. As a consequence of the small volumes used for spotting and the assays, evaporation often deteriorates the quality, reproducibility of spots, and the overall
Wolfram Gronwald et al.
Kidney international, 79(11), 1244-1253 (2011-03-11)
Autosomal dominant polycystic kidney disease (ADPKD) is a frequent cause of kidney failure; however, urinary biomarkers for the disease are lacking. In a step towards identifying such markers, we used multidimensional-multinuclear nuclear magnetic resonance (NMR) spectroscopy with support vector machine-based
Nannan Zhao et al.
Endocrine, 64(3), 544-551 (2019-03-30)
Betaine contains three methyl groups and plays a critical role in regulating glucose and lipid metabolism via epigenetic modifications. However, it is unclear whether prenatal betaine intake could affect cholesterol metabolism of progeny through DNA methylation. Hence, pregnant rats were
Minal J Menezes et al.
Human molecular genetics, 24(8), 2297-2307 (2015-01-04)
Functional defects of the mitochondrial translation machinery, as a result of mutations in nuclear-encoded genes, have been associated with combined oxidative phosphorylation (OXPHOS) deficiencies. We report siblings with congenital sensorineural deafness and lactic acidemia in association with combined respiratory chain
Banafsheh Amiraslani et al.
Iranian biomedical journal, 16(2), 84-89 (2012-07-18)
Neuroinflammation, as a major outcome of microglia activation, is an important factor for progression of neurodegenerative disorders including Alzheimer's disease and Parkinson's disease. Microglial cells, as the first-line defense in the central nervous system, act as a source of neurotoxic
Eugene F Diekman et al.
JAMA neurology, 71(2), 188-194 (2013-12-11)
The impact of betaine treatment on outcome in patients with severe methylenetetrahydrofolate reductase (MTHFR) deficiency is presently unclear. To investigate the effect of betaine treatment on development and survival in patients with severe MTHFR deficiency. MEDLINE, EMBASE, and Cochrane databases
Molly Adrian et al.
Journal of psychiatric research, 68, 125-133 (2015-08-01)
The objective of this study was to apply a Bayesian statistical analytic approach that minimizes multiple testing problems to explore the combined effects of chronic low familial support and variants in 12 candidate genes on risk for a common and
Theodore Spilker et al.
Journal of clinical microbiology, 47(8), 2607-2610 (2009-06-06)
PCR primers targeting loci in the current Burkholderia cepacia complex multilocus sequence typing scheme were redesigned to (i) more reliably amplify these loci from B. cepacia complex species, (ii) amplify these same loci from additional Burkholderia species, and (iii) enable
Michaela S Lesjak et al.
Cell adhesion & migration, 8(5), 499-508 (2014-12-09)
Endometrial carcinoma differential 3 (EDI3) was the first member of the glycerophosphodiesterase (GDE) protein family shown to be associated with cancer. Our initial work demonstrated that endometrial and ovarian cancer patients with primary tumors overexpressing EDI3 had a higher risk
Strategies to improve medication reconciliation.
Oscar M P Jolobe
The American journal of medicine, 126(12), e49-e49 (2013-11-23)
Joachim Jankowski et al.
Arteriosclerosis, thrombosis, and vascular biology, 23(7), 1231-1238 (2003-05-10)
Diadenosine polyphosphates have been demonstrated to be involved in the control of vascular tone as well as the growth of vascular smooth muscle cells and hence, possibly, in atherogenesis. In this study we investigated the question of whether diadenosine polyphosphates
Yixing Zhai et al.
The international journal of biochemistry & cell biology, 65, 12-19 (2015-05-20)
Ribonuclease like 5 (Rnasel5) is a novel member of the zebrafish ribonuclease A family and its expression is increased during early embryogenesis. However, the in vivo biological function of Rnasel5 remains to be elucidated. Here, we report that knockdown of
Xiaoxia Li et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 33(5), 611-617 (2017-05-13)
Deep eutectic solvents (DES) are potential ecofriendly surfactants for the preparation of materials. In this study, both molecularly imprinted polymers (MIPs) and mesoporous siliceous materials (MSMs) were modified by betaine-based DES. Six materials were employed as solid phase extraction (SPE)
S Mukherjee et al.
International journal of cosmetic science, 37(4), 371-378 (2015-02-07)
Skin irritation in personal cleansing has been correlated with surfactant binding with stratum corneum proteins. Polar and non-polar oils are increasingly being used in cleansing formulations which contain high (10-15%) level of anionic and non-ionic surfactants. However, the effects of
Guilherme S Mazzini et al.
Pancreas, 44(4), 619-625 (2015-03-31)
Extracellular purines are a component of the systemic inflammatory response, and their levels are modulated by ectonucleotidases. In addition, nucleotide hydrolysis releases phosphate. We studied serum phosphate levels as a predictor of severity in acute pancreatitis (AP) and their correlation
Valeria Tomati et al.
Scientific reports, 5, 12138-12138 (2015-07-18)
Cystic fibrosis (CF) is caused by mutations in the CFTR chloride channel. Deletion of phenylalanine 508 (F508del), the most frequent CF mutation, impairs CFTR trafficking and gating. F508del-CFTR mistrafficking may be corrected by acting directly on mutant CFTR itself or
Jingqing Chen et al.
Journal of physiology and biochemistry, 71(3), 405-413 (2015-06-17)
Nonalcoholic fatty liver disease (NAFLD) is now the most common cause of chronic liver disease among children and adolescents in the developed world. Betaine, as a methyl donor, recently has been demonstrated to exert its hepatoprotective effects through rectifying the
Wolfram Gronwald et al.
Analytical chemistry, 80(23), 9288-9297 (2009-06-25)
Two-dimensional (2D) nuclear magnetic resonance (NMR) spectroscopy is a fairly novel method for the quantification of metabolites in biological fluids and tissue extracts. We show in this contribution that, compared to 1D 1H spectra, superior quantification of human urinary metabolites
Jun Cao et al.
Journal of biomedical nanotechnology, 9(11), 1847-1861 (2013-09-26)
pH-sensitive micelles are considered promising carriers for tumor targeted drug delivery. In this study, novel pH-sensitive star-shape copolymers of amphiphilic poly(epsilon-caprolactone)-b-poly(N, N-diethylaminoethyl methacrylate)-r-poly(N-(3-sulfopropyl)-N-methacryloxyethy-N, N-diethylammoniumbetaine) (4sPCLDEAS) are designed and synthesized with the combination of ring opening polymerization (ROP) and atom radical
D Knopman et al.
Alzheimer disease and associated disorders, 15(3), 162-165 (2001-08-28)
We investigated the safety and tolerability of betaine in patients with Alzheimer disease (AD). Betaine is an alternative methyl donor, distinct from the folate-and cobalamin-dependent conversion pathway between homocysteine and methionine. Betaine has been used successfully to reduce homocysteine levels
Lei Gao et al.
International journal of molecular sciences, 22(14) (2021-07-25)
The effective cryopreservation of mesenchymal stem cells (MSCs) is indispensable to the operation of basic research and clinical transplantation. The prevalent protocols for MSC cryopreservation utilize dimethyl sulfoxide (DMSO), which is easily permeable and able to protect MSCs from cryo-injuries
Vishnudutt Purohit et al.
The American journal of clinical nutrition, 86(1), 14-24 (2007-07-10)
This report is a summary of a symposium on the role of S-adenosylmethionine (SAM), betaine, and folate in the treatment of alcoholic liver disease (ALD), which was organized by the National Institute on Alcohol Abuse and Alcoholism in collaboration with
Jason W Sahl et al.
PloS one, 10(3), e0121052-e0121052 (2015-03-25)
Burkholderia pseudomallei is the causative agent of melioidosis and a potential bioterrorism agent. In the development of medical countermeasures against B. pseudomallei infection, the US Food and Drug Administration (FDA) animal Rule recommends using well-characterized strains in animal challenge studies.
M S Hedemann et al.
Journal of animal science, 90 Suppl 4, 200-202 (2013-02-13)
During transition from late gestation to lactation, the sow undergoes large and sudden metabolic changes to adapt from anabolic to catabolic metabolism. Little is known about changes in nutrient uptake and intermediary metabolism of transition sows. This study was undertaken
Min Jung Kim
Animal cells and systems, 22(5), 289-298 (2018-11-22)
Betaine is a key metabolite of the methionine cycle and known for attenuating alcoholic steatosis in the liver. Recent studies have focused on the protection effect of betaine in mitochondrial regulation through the enhanced oxidative phosphorylation system. However, the mechanisms
Sharon E Jacob et al.
Dermatitis : contact, atopic, occupational, drug, 19(3), 157-160 (2008-07-17)
Cocamidopropyl betaine (CAPB) is an amphoteric synthetic detergent that has been increasingly used in cosmetics and personal hygiene products (eg, shampoos, contact lens solutions, toothpaste detergents, makeup removers, bath gels, skin care products, cleansers, liquid soaps, antiseptics, and gynecologic and
Poliana Coelho Cabral et al.
Nephrology (Carlton, Vic.), 10(5), 459-463 (2005-10-14)
The objective of this study was to assess the vitamin A and zinc serum levels in patients undergoing haemodialysis (HD) in the city of Recife, in the north-eastern region of Brazil. The study comprised 55 patients and 28 healthy controls.
Luciana Kase Tanno et al.
PloS one, 10(8), e0136141-e0136141 (2015-08-21)
Although aromatic anticonvulsants are usually well tolerated, they can cause cutaneous adverse drug reactions in up to 10% of patients. The clinical manifestations of the antiepileptics-induced hypersensitivity reactions (AHR) vary from mild skin rashes to severe cutaneous drug adverse reactions
R De Smet et al.
Clinical chemistry, 47(5), 901-909 (2001-04-28)
Several studies have pointed to a release of drugs or protein-bound solutes from their binding sites during heparinization. The effect is attributed to the metabolism of triglycerides to free fatty acids (FFAs), which compete with drugs for protein binding sites.
M F Abdelmalek et al.
The American journal of gastroenterology, 96(9), 2711-2717 (2001-09-25)
No effective therapy currently exists for patients with nonalcoholic steatohepatitis (NASH). Betaine, a naturally occurring metabolite of choline, has been shown to raise S-adenosylmethionine (SAM) levels that may in turn play a role in decreasing hepatic steatosis. Our aim was
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