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Showing 1-30 of 6326 results for "E2385" within Papers
Nicholas J Schaub et al.
PloS one, 10(9), e0136780-e0136780 (2015-09-05)
The surface of aligned, electrospun poly-L-lactic acid (PLLA) fibers was chemically modified to determine if surface chemistry and hydrophilicity could improve neurite extension from chick dorsal root ganglia. Specifically, diethylenetriamine (DTA, for amine functionalization), 2-(2-aminoethoxy)ethanol (AEO, for alcohol functionalization), or
Corie L Charpentier et al.
The Journal of experimental biology, 218(Pt 21), 3381-3390 (2015-11-06)
Several predator avoidance strategies in zooplankton rely on the use of light to control vertical position in the water column. Although light is the primary cue for such photobehavior, predator chemical cues or kairomones increase swimming responses to light. We
Stefania Marcheggiani et al.
International journal of environmental research and public health, 12(5), 5505-5527 (2015-05-27)
Current knowledge about the spread of pathogens in aquatic environments is scarce probably because bacteria, viruses, algae and their toxins tend to occur at low concentrations in water, making them very difficult to measure directly. The purpose of this study
Marilyn Cyr et al.
Behavioural brain research, 278, 107-114 (2014-09-27)
Cholinergic neurons of the pedunculopontine tegmental nucleus (PPTg) are thought to be involved in cognitive functions such as sustained attention, and lesions of these cells have been documented in patients showing fluctuations of attention such as in Parkinson's disease or
Elisabetta Buommino et al.
Journal of medical microbiology, 64(Pt 2), 180-184 (2015-01-30)
Malassezia pachydermatis is part of the normal cutaneous microbiota of most warm-blooded vertebrates and is associated with otitis externa and seborrhoeic dermatitis in dogs and cats. In this study, we evaluated the growth capacity of nine M. pachydermatis strains on
Ali Es-Haghi et al.
Talanta, 128, 231-236 (2014-07-26)
Sol-gel based solid-phase microextraction fibers supported by a stainless steel wire were fabricated and employed for GC-MS determination of oxadiargyl in real samples. The fibers were based on four compounds with different polarity: polar and non-polar (end-capped) poly(dimethylsiloxane) (PDMS), polyethylene
Erming Tian et al.
Genes, chromosomes & cancer, 54(11), 692-701 (2015-07-30)
The growth and survival factor hepatocyte growth factor (HGF) is expressed at high levels in multiple myeloma (MM) cells. We report here that elevated HGF transcription in MM was traced to DNA mutations in the promoter alleles of HGF. Sequence
Pablo R S Oliveira et al.
Journal of immunology (Baltimore, Md. : 1950), 194(6), 2664-2672 (2015-02-13)
The outcome of Leishmania infections varies substantially, depending on the host and the parasite strain; infection may be asymptomatic or cause mild or severe skin ulcers (cutaneous leishmaniasis [CL]), limited or disseminated lesions, or lethal visceral disease. We previously reported
Kai Wu et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(12), 5111-5121 (2014-08-26)
Genetic mutations in parkin or pink1 are the most common causes of familial Parkinson's disease. PINK1 and Parkin are components of a mitochondrial quality control pathway that degrades dysfunctional mitochondria via autophagy. Using a candidate gene approach, we discovered that
Ilias Kazanis et al.
Experimental neurology, 269, 75-89 (2015-03-31)
The presence of neural stem/progenitor cells (NSPCs) in specific areas of the central nervous system (CNS) supports tissue maintenance as well as regeneration. The subependymal zone (SEZ), located at the lateral ventricle's wall, represents a niche for NSPCs and in
Ming-Gene Tu et al.
Journal of materials science. Materials in medicine, 26(12), 276-276 (2015-11-07)
The use of calcium silicate (CS) cement holds great promise for bone substitute biomaterials. However, the effects of CS on osteoblast and macrophage cells are not fully understood. This study examines cell proliferation and differentiation of mono- or co-cultured MC3T3-E1
Sampa Maiti et al.
Talanta, 141, 116-121 (2015-05-13)
A new, simple, rapid and selective spectrophotometric method has been developed for detection and estimation of butanol in fermentation broth. The red colored compound, produced during reduction of diquat-dibromide-monohydrate with 2-mercaptoethanol in aqueous solution at high pH (>13), becomes purple
Lan Yao et al.
BMC complementary and alternative medicine, 15, 314-314 (2015-09-09)
Diabetic nephropathy is a serious complication of diabetes whose development process is associated with inflammation, renal hypertrophy, and fibrosis. Coreopsis tinctoria Nutt, traditionally used as a healthcare tea, has anti-inflammatory, anti-hyperlipidemia, and glycemic regulation activities. The aim of our study
Bo Jiang et al.
Applied and environmental microbiology, 81(1), 260-271 (2014-10-26)
With a completely reengineered and humanized glycosylation pathway, glycoengineered Pichia pastoris has emerged as a promising production host for the manufacture of therapeutic glycoproteins. However, the extensive genetic modifications have also negatively affected the overall fitness levels of the glycoengineered
M Argun et al.
Eye (London, England), 28(6), 752-760 (2014-03-08)
Under conditions of oxidative stress, cell apoptosis is triggered through the mitochondrial intrinsic pathway. Increased levels of reactive oxygen species (ROS) are linked to excess cell loss and mediate the initiation of apoptosis in a diverse range of cell types.
Cindy S E Tan et al.
Journal of virology, 88(24), 14030-14039 (2014-09-26)
Viruses commonly infect the respiratory tract. Analyses of host defense have focused on the lungs and the respiratory epithelium. Spontaneously inhaled murid herpesvirus 4 (MuHV-4) and herpes simplex virus 1 (HSV-1) instead infect the olfactory epithelium, where neuronal cilia are
Qihua Ling et al.
Archives of virology, 160(4), 1105-1112 (2015-02-18)
Although the single-nucleotide polymorphism (SNP) rs12979860 in the IL28B gene is a better predictor of sustained virological response to treatment of chronic hepatitis C (CHC) than other baseline factors, some CHC patients with the favorable C allele cannot achieve a
Zhengzong Wu et al.
Food chemistry, 194, 671-679 (2015-10-17)
The application of attenuated total reflectance infrared spectroscopy (ATR-IR), Raman spectroscopy (RS) and combination of ATR-IR and RS for measurements of total antioxidant capacity (TAC) and total phenolic content (TPC) of Chinese rice wine (CRW) were investigated in this study.
Juan Manuel Torres et al.
The Journal of clinical investigation, 124(12), 5239-5248 (2014-11-05)
Heterotrimers composed of B cell CLL/lymphoma 10 (BCL10), mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), and caspase recruitment domain-containing (CARD) family adaptors play a role in NF-κB activation and have been shown to be involved in both the innate
Yu Zhou et al.
Ophthalmic genetics, 36(1), 43-49 (2014-11-25)
Genetic factors have been studied extensively for their role in the pathogenesis of primary open angle glaucoma (POAG). This study was conducted to investigate whether manganese superoxide dismutase (SOD2) variants play a significant role in POAG in a Chinese population.
Liang Hu et al.
Materials science & engineering. C, Materials for biological applications, 47, 313-324 (2014-12-11)
We used a combination of mesoporous silica nanospheres (MSN) and layer-by-layer (LBL) self-assembly technology to establish a new oral sustained drug delivery system for the poorly water-soluble drug felodipine. Firstly, the model drug was loaded into MSN, and then the
Yaqin Hu et al.
Carbohydrate polymers, 134, 808-816 (2015-10-03)
Sea cucumber fucoidan is a major bioactive component of sea cucumber. The structures of fucoidans have significant influences on their biological activities. The present study clarified the delicate structure of a fucoidan from Pearsonothuria graeffei. Fucoidan was obtained after papain
K L Schully et al.
International journal of pharmaceutics, 495(2), 849-861 (2015-10-03)
Melioidosis, a potentially lethal disease of humans and animals, is caused by the soil-dwelling bacterium Burkholderia pseudomallei. Due to B. pseudomallei's classification as a Tier 1 Select Agent, there is substantial interest in the development of an effective vaccine. Yet
Gang Chen et al.
Journal of endodontics, 41(7), 1091-1099 (2015-04-18)
During tooth development, cells originating from the neural crest serve as precursors to the cells in the dental follicle and dental papilla. Therefore, the current study aimed to understand the associations of cranial neural crest cells (CNCCs), dental follicle cells
Serena Deiana et al.
Behavioural pharmacology, 26(8 Spec No), 748-765 (2015-08-20)
Deficiencies in social activities are hallmarks of numerous brain disorders. With respect to schizophrenia, social withdrawal belongs to the category of negative symptoms and is associated with deficits in the cognitive domain. Here, we used the N-methyl-D-aspartate receptor antagonist dizocilpine
Ingrid R Cordeiro et al.
Biology open, 4(9), 1180-1193 (2015-09-01)
Human adipose-derived stromal cells (hADSC) are a heterogeneous cell population that contains adult multipotent stem cells. Although it is well established that hADSC have skeletal potential in vivo in adult organisms, in vitro assays suggest further differentiation capacity, such as
Ra Ham Lee et al.
Oncology reports, 33(2), 631-638 (2014-12-02)
7,8-Dihydroxyflavone (7,8-DHF) is a member of the flavonoid family and has recently been identified as a brain-derived neurotrophic factor mimetic that selectively activates tropomyosin-receptor kinase B with high affinity. The antioxidant and anticancer effects of 7,8-DHF have been reported. However
Vendula Studentova et al.
Folia microbiologica, 60(2), 119-129 (2014-09-30)
Carbapenemase-mediated resistance to carbapenems in Enterobacteriaceae has become the main challenge in the treatment and prevention of infections recently. The partially unnoticed spread of OXA-48-type carbapenemase producers is usually assigned to low minimum inhibitory concentrations (MICs) of carbapenems that OXA-48-producing
Florian Mertes et al.
BMC genomics, 16, 925-925 (2015-11-14)
Next Generation Sequencing has proven to be an exceptionally powerful tool in the field of genomics and transcriptomics. With recent development it is nowadays possible to analyze ultra-low input sample material down to single cells. Nevertheless, investigating such sample material
Weifang Zhang et al.
Journal of virology, 89(5), 2553-2562 (2014-12-19)
Specific types of human papillomavirus (HPV) are strongly associated with the development of cervical carcinoma. The HPV E6 oncoprotein from HPV degrades p53 and abrogates cell cycle checkpoints. Nonetheless, functional p53 has been observed in cervical cancer. We have previously
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