Reaction design and optimization

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Phosgene is 170 times more reactive than TP, the main phosgene substitute. Therefore, reactions with phosgene can be carried out under much milder conditions than with TP. Compounds will react faster and at lower temperatures (often at -78°C), preserving sensitive

Chiral Vicinal Diamines for Asymmetric Synthesis

Chiral vicinal diamines are of tremendous interest to the synthetic chemist as they are found in many chiral catalysts and pharmaceuticals.

Asymmetric Transfer Hydrogenation

The use of transfer hydrogenation to reduce alkenes, carboxyl groups, ketones, or imines has become very popular.

Oxidizing and Reducing Agents

Oxidation and reduction reactions are some of the most common transformations encountered in organic synthesis

Mild Mg – Halogen Exchange

Substantial progress has been made in magnesium–halogen exchange reactions used for the preparation of functionalized Grignard reagents containing sensitive moieties such as ester or cyano groups.

Alkali Metal Silica Gels from SiGNa

SiGNa Chemistry has recently developed a technology for encapsulating alkali metals into nano-structured porous oxides to create stable, free flowing powders with varying reactivities (based on the intended application).

Scale-Up Guide: Suzuki-Miyaura Cross-Coupling Reaction

All of the preformed catalysts used in the kit are air and moisture stable complexes in their commercially available form.

PYBOX Ligand - Large Binding Site & Rigid Scaffold

The PYBOX ligand, consisting of a pyridine ring flanked by two oxazoline groups, was introduced in 1989 by Nishiyama.

ChiPros Chiral Amines

Chiral amines play an important role in stereoselective organic synthesis. They are used directly as resolving agents, building blocks, or chiral auxiliaries.

Chiral Alcohols

Green Chemistry: Replacing Hazardous Solvents & Creating Value from "Waste"

In the first part of this webinar, hear from Professor Cameron Weber about some ways that alternative solvents such as ionic liquids and deep eutectic solvents can be designed towards the replacement of hazardous solvents and the creation of more

TPGS-750-M: Second-Generation Amphiphile for Organometallic Chemistry in Water at Room Temperature

Lipshutz and co-workers have recently developed a second generation technology to their original PTS-enabling surfactant based on the polyoxyethanyl-α-tocopheryl succinate derivative, TPGS-750-M.

Asymmetric Epoxidation Using Shi Catalyst

Catalytic asymmetric epoxidation of alkenes has been the focus of many research efforts over the past two decades, the best known methods probably being those developed by Sharpless and Jacobsen-Katsuki.

KitAlysis High-Throughput Palladium Precatalyst Cross-Coupling Reaction Screening Kit

Materials Included in your KITALYSIS-24PD-2PK High-Throughput Screening Kit

Safer, More Efficient and Greener Organic Chemistry Processes with Flow Technology

This webinar will showcase the synergistic integration of new process technologies and in silico approaches in organic synthesis, targeting high-value added compounds.

Metal–Olefin Interactions: Classical Bonding Motifs Inspire Innovations in Catalysis

Explore in this seminar olefin reactivity via transition metal catalysis, focusing on advances in selective catalytic olefin functionalization and the design of stable low-valent metal precatalysts.

KitAlysis™ High-Throughput Copper C-N Cross-Coupling Reaction Screening Kit

KitAlysis™ Cu C-N (Buchwald-Hartwig) cross-coupling high-throughput screening kit. Detailed Set-Up User Guide and a downloadable excel file for calculations.

SnAP Reagents

SnAP Reagents facilitate synthesis of saturated N-heterocycles for diverse structures.

BASIONICS™ Ionic Liquids

BASIONICS™ Ionic Liquids offer diverse properties for varied applications in the BASF portfolio.

Trialkylphosphine for MBH Reactions

Amines and phosphines in nucleophilic catalysis are discussed, addressing the air sensitivity of phosphines.

Dess–Martin Periodinane

Dess-Martin Periodinane enables mild oxidation of alcohols to aldehydes and ketones suitable for synthesizing complex intermediates.

Red-Al^® Reducing Agent

Red-Al® is a versatile and safe reducing agent, serving as a substitute for LiAlH4 in many reactions, with nonpyrophoric properties.

Selective 1,2-Additions with LaCl3·2LiCl

Grignard reagent's 1,2-addition to ketones is powerful but selective issues often arise from competitive alpha-deprotonation.

Jacobsen Thioureas

Chiral thioureas serve as versatile organocatalysts, facilitating enantioselective reactions with a broad substrate scope.

CBILS© offers a simple, elegant synthetic method for the production of ionic liquids, developed by the Austrian company proionic.

Fluoroalkylation: Expansion of Togni Reagents

Fluoroalkylation toolbox expands with various reagents for late-stage fluoroalkylation in organic synthesis and medicinal chemistry.

Asymmetric Reduction of Ketones

Novel ligands enable efficient ketone reduction for chiral building block synthesis.

Metal Scavengers

Metal compound synthesis emphasizes reducing residual metal levels due to physiological activities of metal ions in bioactive compounds.

Glycosyltransferases: Tools for Synthesis and Modification of Glycans

Explore tools for glycosyltransferase synthesis and modification of glycans, such as glycosyltransferases and nucleotide sugar donors.

Step-by-Step Guide for KitAlysis™ Suzuki-Miyaura Cross-Coupling Reaction Screening Kit

A step-by-step protocol guide for KitAlysis Suzuki-Miyaura Cross-Coupling Reaction Screening Kit.

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