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Biodegradable Polyester Based Nanoparticle Formation by Miniemulsion Technique

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

Poly(ethylene glycol) (PEG) and Synthetic PEG Derivatives for Tissue Engineering and Cell Delivery

Highlighting new synthetic modifications of PEG to improve the mechanical properties and degradation of resulting hydrogels in tissue engineering applications.

Biomedical Implant Devices Fabricated from Low Young’s Modulus Titanium Alloys Demonstrating High Mechanical Biocompatibility

Biomedical implants are essentially foreign substances within the human body that must survive many years’ exposure to demanding mechanical and physiological conditions. Despite these challenges, metal implants have been widely used to substitute for or rebuild hard tissues such as

Photo-Crosslinkable Gelatin Hydrogel: Versatile Materials for (High Resolution) Additive Manufacturing

Discussion of synthetic modifications to gelatin, improving the three-dimensional (3D) print resolution, and resulting material properties.

DNA Methylation and Bisulfite Conversion

There are several common ways to determine whether a gene contains methylated DNA. Since mammalian methylation occurs at cytosines, researchers take advantage of the fact that methylated cytosine (meC) is stable to bisulfite treatment but unmethylated cytosine is transformed to

Phosgene and Phosgene Substitutes

Phosgene is 170 times more reactive than TP, the main phosgene substitute. Therefore, reactions with phosgene can be carried out under much milder conditions than with TP. Compounds will react faster and at lower temperatures (often at -78°C), preserving sensitive

Red-Al® Reducing Agent

Red-Al®, or sodium bis(2-methoxyethoxy)aluminum dihydride (Vitride®, SMEAH), is a versatile reducing agent and a good substitute for LiAlH4 in many reactions. Red-Al® is nonpyrophoric, although still moisture-sensitive, and is available in solution, allowing for easier handling compared to LiAlH4.

Bis(2-methoxyethyl)aminosulfur Trifluoride (Deoxo-Fluor®)

This technical article discusses Bis(2-methoxyethyl)aminosulfur Trifluoride (Deoxo-Fluor®).

Task-Specific Ionic Liquids

Task-Specific Ionic Liquids (TSILs) for the selective liquid/liquid extraction of heavy metals from aqueous systems were first published by Robin D. Rogers et al. in the year 2001.

BASIONICS™, BASF’s Portfolio of Ionic Liquids

Under the trade name BASIONICS™, BASF offers a portfolio of Ionic Liquids—mainly based on imidazolium cations. The BASIONICS™ portfolio opens up a broad range of basic properties of Ionic Liquids and is classified into standard, acidic, basic, liquid at RT

Chiral Vicinal Diamines for Asymmetric Synthesis

Chiral vicinal diamines are of tremendous interest to the synthetic chemist as they are found in many chiral catalysts and pharmaceuticals.

Navigating Fragrance Allergens

Food allergens are well known and codified by most global food regulatory agencies. Regulators and consumers require that food allergens be clearly displayed on packages.

Selective 1,2-Additions with LaCl3·2LiCl

While the 1,2-addition of Grignard reagents to ketones is undoubtedly a powerful transformation, oftentimes selectivity issues arising from competitive alpha-deprotonation detract from the use of these reagents.

Asymmetric Transfer Hydrogenation

The use of transfer hydrogenation to reduce alkenes, carboxyl groups, ketones, or imines has become very popular.

Oxidizing and Reducing Agents

Oxidation and reduction reactions are some of the most common transformations encountered in organic synthesis

Mild Mg – Halogen Exchange

Substantial progress has been made in magnesium–halogen exchange reactions used for the preparation of functionalized Grignard reagents containing sensitive moieties such as ester or cyano groups.

Heterocyclic Aryne Precursors:
New Opportunities for the Synthesis of
Highly Substituted Indoles and Pyridines

New and efficient methods for the synthesis of functionalized heterocycles are highly sought after.

Salen Ligands

Salen Ligands: In 1990, Jacobsen and Katsuki independently published the first reports of salen used as ligands with manganese for asymmetric epoxidation reactions.

Alkali Metal Silica Gels from SiGNa

SiGNa Chemistry has recently developed a technology for encapsulating alkali metals into nano-structured porous oxides to create stable, free flowing powders with varying reactivities (based on the intended application).

Quantum Dots: An Emerging Class of Soluble Optical Nanomaterials

We presents an article concering Quantum Dots: An Emerging Class of Soluble Optical Nanomaterials.

Polymer-Clay Nanocomposites: Design and Application of Multi-Functional Materials

One of the desirable end-goals of materials science research is the development of multi-functional materials. These materials are defined as compositions that bring more than one property enhancement to a particular application, thus allowing the material to replace more than

Photonic Optical Materials Tutorial

The field of organic nonlinear optics has come a long way since the its triggering development in 1970. In that year, Davydov et al. reported a strong second harmonic generation (SHG) in organic molecules having electron donor and acceptor groups

High-Performance Semiconductor Polymers Based on Diketopyrrolopyrrole and Thienothiophene

The development of high-performance conjugated organic molecules and polymers has received widespread attention in industrial and academic research.

Introduction to Gold Nanoparticles – Properties & Applications in Life Science

Gold nanoparticles are particles with diameters in the 1-100 nm range and have unique optical and physical properties, the most pronounced being the intense absorbance and scattering of incident light at its surface plasmon resonance wavelength.

Nano Minerals: Nanoclays

Nanoclays are nanoparticles of layered mineral silicates. Montmorillonite, bentonite, and halloysite nanoclays and organoclays are used in polymer-clay nanocomposites, as rheology modifiers, and drug delivery carriers.

Recent Progress in Spintronic Materials

Spin-based electronic (spintronic) devices offer significant improvement to the limits of conventional charge-based memory and logic devices which suffer from high power usage, leakage current, performance saturation, and device complexity.

Advancements in the Fabrication of Integrated Organic Electronics

Professor Tokito and Professor Takeda share their new materials, device architecture design principles, and performance optimization protocols for printed and solution-processed, low-cost, highly flexible, organic electronic devices.

Advanced Materials for Magnetic Cooling

Today, near-room-temperature refrigeration is almost entirely based on a vapor-compression refrigeration cycle.

Fluorinated Hyperbranched Polymers

Fluorocarbon polymers, like small-molecule fluorocarbons, exhibit increased thermal stability, hydrophobicity, lipophobicity, improved chemical resistance, and decreased intermolecular attractive forces in comparison to their hydrocarbon analogs.

Silica-coated Gold Nanoparticles: Surface Chemistry, Properties, Benefits and Applications

In the past few decades, research and commercial use of gold nanoparticles has rapidly expanded into fields extending from biomedical engineering to photovoltaics. Most applications take advantage of the excellent optical properties of gold nanoparticles, which can be fine-tuned by

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