Protein expression

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Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

Read review on VEGF signaling pathway (Vascular endothelial growth factor (VEGF)/VEGF receptor) and find related products.

Utilizing ISOGRO® Supplementation of M9 Minimal Media to Enhance Recombinant Protein Expression

Utilizing ISOGRO® Supplementation of M9 Minimal Media to Enhance Recombinant Protein Expression.

p53: DNA Damage Response and Cancer

p53 regulates gene expression, cell cycle control and functions as a tumor suppressor. Inactivation of p53 is closely tied to cancer development.

Cloning & Expression Vectors

Expression Vectors for Bacterial, Mammalian and Insect Cell Systems. Featured are a variety of tags, promoters and elements for secretion, transient, stable and bicistronic expression.

Duolink® PLA Technology for Neuroscience Applications

Duolink® proximity ligation assay used to study neuron interactions furthering neuroscience research.

Lipid-induced Insulin Resistance

Lipid Induced Insulin Resistance

NF-κB and Inflammation

Chronic inflammation is an underlying factor in the development and progression of many of the chronic diseases of aging, such as arthritis, atherosclerosis, diabetes, and cancer.

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Signal Peptide Optimization: Effect On Recombinant Monoclonal IgG Productivity, Product Quality And Antigen-Binding Affinity

A signal peptide is a 5-30 amino acid (aa) peptide present at the N-terminus of secretory proteins.

How to Optimize Duolink® PLA for Flow Cytometry Detection

Considerations for proper experimental design, preparation and execution of the Duolink® PLA for flow cytometry protocol.

Duolink® PLA Troubleshooting Guide

Support information including tips and tricks, frequently asked questions, and basic troubleshooting.

Tag Removal Proteases for Recombinant Protein Purification

Proteases for biotinylated tag removal for protein purification workflows with related reagents and technical resources.

Glycosaminoglycan Sulfation and Signaling

Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.

Troubleshooting Guide for Duolink® PLA for Flow Cytometry Detection

General tips and tricks for proper experiment execution, aid in identifying potential problems, and provide solutions to ensure a successful Duolink® PLA experiment for flow cytometry.

FLAG® Tag Bacterial and Mammalian Expression Vectors

FLAG® and 3xFLAG® expression vectors and products for bacterial and mammalian expression vectors, detection and purification of proteins.

Cannabinoid Receptors

We offer many products related to cannabinoid receptors for your research needs.

GABAC Receptors

Introduction to GABAC receptors as well as modulators and other products for your research needs.

Serotonin Receptors

We offer many products related to serotonin receptors for your research needs.

Nuclear Receptors (Non-Steroids)

We offer many products related to non-steroid nuclear receptors for your research needs.

Sigma Receptors

Sigma receptors may constitute favorable targets for drug design in conditions such as psychiatric and movement disorders, amnesia, depression, cancer, inflammation and cocaine addiction.

Histamine Receptors

We offers many products related to histamine receptors for your research needs.

α2-Adrenoceptors

Learn about alpha-2 adrenoceptor and its subtypes, mediated responses, and applications of agonists. Included is a list of available products and a comparison table.

Dopamine Receptors

We offer many products related to dopamine receptors for your research needs.

Cytokine Receptors (Hematopoetin Receptor Family)

We offer many products related to Cytokine Receptors (Hematopoetin Receptor Family) for your research needs.

EGFR

Our company offers many products related to EGFR for your research needs.

FGFR

We offer many products related to FGFR for your research needs.

Canonical Wnt / β-Catenin Signaling

We review the Wnt signaling pathway (also, canonical Wnt or beta (β)-catenin pathway) and provide links to related products at sigmaaldrich.com.

Residual Peroxide Determination in Food Packaging

ECM microenvironment shapes cell processes; engineering advances needed for complex control in cell and tissue studies.

3xFLAG® System Expression Vectors for Ultra-Sens

The 3xFLAG system enhances fusion protein detection, offering improved sensitivity over traditional methods.

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