- Synthesis and in vitro study of novel Mannich bases as antibacterial agents.
Synthesis and in vitro study of novel Mannich bases as antibacterial agents.
Bioorganic & medicinal chemistry letters (2004-12-08)
Sheela Joshi, Navita Khosla, Deepak Khare, Rakesh Sharda
PMID15582443
ABSTRACT
A series of novel Mannich bases derived from 5-chloro-2-methoxybenzamide and sulfonamides/amines have been synthesised and the antibacterial activities were evaluated against various Gram positive and Gram negative strains of bacteria. Some of the synthesized compounds showed superior in vitro activities as compared to their parent sulfonamides.
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