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  • [Remarkable improvement in dyspnea following bronchofiberscopic ethanol injection therapy -a case report].

[Remarkable improvement in dyspnea following bronchofiberscopic ethanol injection therapy -a case report].

Gan to kagaku ryoho. Cancer & chemotherapy (2014-01-08)
Kiyomi Shimoda, Yuji Shiraishi, Takashi Harano, Miyako Hiramatsu, Hidefumi Kita, Naoya Katsuragi
ABSTRACT

A 69-year-old man with squamous cell carcinoma( SCC) of the left lower lobe of the lung underwent lobectomy. One year later, radiography performed during check-up revealed pneumonia. After 1 week, he was admitted to the hospital because of dyspnea. Three tumors in his trachea and bronchus had narrowed the respiratory tract, and these were diagnosed as recurrence of SCC. The patient was treated with radiation and bronchofiberscopic ethanol injection (BEI) therapy, following which the tumors reduced remarkably in size; he recovered from respiratory insufficiency and was able to go home. He stayed home for 2 months; however, tumor enlargement was detected subsequently and the patient was at risk of suffocation. This time, the patient received combination therapy that included radiation, TS-1, and BEI. Subsequently, his respiratory airway reopened. BEI offers a quick and safe treatment option and has a rapid effect; therefore, we consider it useful for the treatment of malignant tracheobronchial stenosis.

MATERIALS
Product Number
Brand
Product Description

Supelco
Ethanol solution, certified reference material, 2000 μg/mL in methanol
Supelco
Ethanol standards 10% (v/v), 10 % (v/v) in H2O, analytical standard
Supelco
Ethanol-400 (10 ampules/kit), 400 mg/dL in H2O, ampule of 10 × 1.2 mL, certified reference material, Cerilliant®
Supelco
Ethanol-500, 500 mg/dL in H2O, ampule of 10 × 1.2 mL, certified reference material, Cerilliant®
Supelco
Ethanol-20 (10 ampules/kit), 20 mg/dL in H2O, ampule of 10 × 1.2 mL, certified reference material, Cerilliant®
Supelco
Ethanol-25, 25 mg/dL in H2O, ampule of 10 × 1.2 mL, certified reference material, Cerilliant®
Supelco
Dehydrated Alcohol, Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
Ethyl alcohol, Pure 190 proof, for molecular biology
Sigma-Aldrich
Ethanol Fixative 80% v/v, suitable for fixing solution (blood films)
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Reagent Alcohol, anhydrous, ≤0.005% water
Sigma-Aldrich
Reagent Alcohol, reagent grade
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Reagent Alcohol, denatured, suitable for HPLC
Sigma-Aldrich
Reagent Alcohol, anhydrous, ≤0.003% water
Supelco
Ethanol Calibration Kit, ampule of 10 × 1.2 mL, certified reference material, Cerilliant®
Sigma-Aldrich
Ethyl alcohol, Pure 200 proof, Molecular Biology
Supelco
Ethanol-10, 10 mg/dL in H2O, pack of 10 × 1.2 mL ampules, certified reference material, Cerilliant®
Supelco
Ethanol-150, 150 mg/dL in H2O, ampule of 10 × 1.2 mL, certified reference material, Cerilliant®
Sigma-Aldrich
Ethyl alcohol, Pure, 190 proof, meets USP testing specifications
Sigma-Aldrich
Ethyl alcohol, Pure, 200 proof, anhydrous, ≥99.5%
Sigma-Aldrich
Ethyl alcohol, Pure, 190 proof, ACS spectrophotometric grade, 95.0%
Sigma-Aldrich
Ethyl alcohol, denatured, denatured, reagent grade
Sigma-Aldrich
Ethyl alcohol, Pure, 200 proof, meets USP testing specifications
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Ethanol, BioUltra, Molecular Biology, ≥99.8%, (absolute alcohol, without additive, A15 o1)
Supelco
Ethanol, standard for GC
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Ethyl alcohol, Pure, 200 proof
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Ethanol, tested according to Ph. Eur.
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Ethyl alcohol, Pure, 200 proof, ACS reagent, ≥99.5%
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Ethanol, puriss. p.a., absolute, ≥99.8% (GC)
Supelco
Ethanol-50, 50 mg/dL in H2O, ampule of 10 × 1.2 mL, certified reference material, Cerilliant®
Supelco
Ethanol-80, 80 mg/dL in H2O, ampule of 10 × 1.2 mL, certified reference material, Cerilliant®