Merck
CN

Aciclovir-resistant herpes keratitis.

Clinical & experimental ophthalmology (2010-05-08)
Keat Choong, Nathan J Walker, Andrew Jg Apel, Michael Whitby
ABSTRACT

Herpes simplex virus (HSV) keratitis is a common cause of ocular morbidity. Resistance to aciclovir is probably under recognized. We describe three cases of aciclovir-resistant herpes simplex virus keratitis treated with systemic foscarnet and present a review of the pharmacological options available to manage this condition.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Acycloguanosine, ≥99% (HPLC), powder
Supelco
Acyclovir, Pharmaceutical Secondary Standard; Certified Reference Material
Aciclovir, European Pharmacopoeia (EP) Reference Standard
USP
Acyclovir, United States Pharmacopeia (USP) Reference Standard