Metabolic Pathways

Dr. Donald Nicholson received his B.Sc. in 1936 and his Ph.D in 1940, both in Chemistry from London University. He then went to work at Boots Pure Drug Company at Nottingham on the development and production of the earliest sulphonamide antibacterial drugs. In 1946 he joined the department of Bacteriology at the School of Medicine in Leeds as an I.C.I Fellow in Chemotherapy and remained there as Lecturer or Senior Lecturer in Microbiology until "retirement" in 1981. Even into his 90s, Dr. Nicholson was actively engaged in the creation of smaller and more detailed "minimaps" and especially "animaps". In recognition of his work, he received an Honorary D.Sc. and was made one of only two Honorary Life Members of the IUBMB.

Learn more about Dr. Nicholson and how he created the Metabolic Pathway Charts.

The Metabolic Pathways Map contains over 500 hyperlinks to our product listings. Just click on the metabolite name or the enzyme's E.C. number to access product information.

The 22nd (2003) edition of the IUBMB-Nicholson Metabolic Pathways Chart contains updated pathways involved in ATP metabolism in the mitochondria and chloroplast. The "backbone" of the map is the Glycolytic Pathway followed by the TCA (Krebs) Cycle and the Respiratory Chain which together lead to the synthesis of ATP by ATP Synthase. ATP is the source of most of the energy required for all life. Many biosynthetic and breakdown pathways of metabolism such as carbohydrates, amino acids, lipids are associated with this backbone and are differentiated by the use of color. Human metabolism is distiguished where possible by the use of black arrows. Some 550 reactions are identified by their IUBMB Enzyme Commission (EC) numbers which are then indexed.

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The 22nd edition of the comprehensive Metabolic Pathways Chart. Features glycolysis, carbohydrate, amino acid, lipid, nucleotide, steroid, vitamin metabolism and much more.

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