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Merck
CN

GABRB1

gamma-aminobutyric acid (GABA) A receptor, beta 1

别名:
物种:
Human GABRB1 (2560), Mouse Gabrb1 (14400), Rat Gabrb1 (25450), Zebrafish gabrb1 (100331377), sheep GABRB1 (101122358), naked mole-rat Gabrb1 (101717539), domestic guinea pig Gabrb1 (100719515), domestic cat GABRB1 (101097640), dog GABRB1 (100687745), cow GABRB1 (282239)
UniProtKB ID:
P18505, B2R6U7, Q16166, Q8TBK3
基因ID:
  • Human(2560) Summary: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008]
  • Mouse(14400) gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
  • Rat(25450) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • Zebrafish(100331377) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • sheep(101122358) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • naked mole-rat(101717539) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • domestic guinea pig(100719515) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • domestic cat(101097640) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • dog(100687745) gamma-aminobutyric acid (GABA) A receptor, beta 1
  • cow(282239) gamma-aminobutyric acid (GABA) A receptor, beta 1

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Small Molecule - Agonist

产品编号
说明
物种
T101
加波沙朵 盐酸盐, solid, ≥98% (HPLC),
物种
human
G019
蝇蕈醇 氢溴酸盐, ≥98% (HPLC), solid,
物种
human
P9159
Piperidine-4-sulfonic acid, ,
物种
human
A2129
γ-氨基丁酸, ≥99%,
物种
human, rat
B4388
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

Small Molecule - Allosteric Modulator

产品编号
说明
物种
D4000
反式-脱氢雄甾酮, ≥99%,
物种
human, rat
PHR1663
普鲁泊福, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
1572503
普鲁泊福, United States Pharmacopeia (USP) Reference Standard,
物种
human
P-076
丙泊酚标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
Y0000016
普鲁泊福, European Pharmacopoeia (EP) Reference Standard,
物种
human

Small Molecule - Antagonist

产品编号
说明
物种
S106
SR-95531, ≥98% (HPLC), powder,
物种
human
D4000
反式-脱氢雄甾酮, ≥99%,
物种
human, rat
1273808
氟马西尼, United States Pharmacopeia (USP) Reference Standard,
物种
human
G7795
Ganaxolone, solid, ≥98% (HPLC),
物种
human, mouse
D126608
普鲁泊福, 97%,
物种
human

Antibodies

产品编号
说明
物种反应性
应用
HPA051297
Anti-GABRB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
SAB4300465
Anti-GABRB1 (Ab-434) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
western blot
SAB5702231
Anti-GABA A Receptor beta 1 (GABRB1) Antibody, clone 1Q3A9, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
western blot
SAB4503762
Anti-phospho-GABA-RB (pSer434) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
AB9680
Anti-GABA A Receptor β 1 Antibody, Chemicon®, from rabbit,
物种反应性
human, mouse, rat
应用
western blot

Small Molecule - Inhibitor

产品编号
说明
物种
N142
NO-711 hydrochloride, ≥98% (HPLC),
物种
human
V8261
(±)-Vigabatrin, ,
物种
human
D126608
普鲁泊福, 97%,
物种
human
PHR1600
托吡酯, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
T-039
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human

Small Molecule - Ligand

产品编号
说明
物种
B4388
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

esiRNA

产品编号
说明
物种
EMU077451
MISSION® esiRNA, targeting mouse Gabrb1,
物种
mouse
EHU002071
MISSION® esiRNA, targeting human GABRB1,
物种
human