1.01544
L -精氨酸 单盐酸盐
EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP
别名:
(S)-(+)-2-氨基-5-[(氨基亚甲基)氨基]戊酸 单盐酸盐, (S)-(+)-精氨酸 盐酸盐
Agency
BP
ChP
JP
Ph. Eur.
USP
质量水平
蒸汽压
<1 Pa ( 20 °C)
产品线
EMPROVE® EXPERT
方案
98.5-101.0% dry basis (perchloric acid titration)
表单
solid
pH值（酸碱度）
5.7 (20 °C, 100 g/L in H2O)
mp
>235 °C
溶解性
water: 730 g/L at 20 °C
密度
1.42 g/cm3 at 20 °C
痕量阴离子
chloride (Cl-): 16.5-17.1%
sulfate (SO42-): ≤200 ppm
痕量阳离子
As: ≤2 ppm
Fe: ≤10 ppm
NH4+: ≤200 ppm
heavy metals (as Pb): ≤10 ppm
应用
liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical
储存温度
2-30°C
SMILES字符串
Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O
InChI
1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1
InChI key
KWTQSFXGGICVPE-WCCKRBBISA-N
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一般描述
Chemicals play an important role in the stabilization of a biologic drug during its manufacturing and formulation process – for instance, by preventing aggregation. We offer a wide range of high-quality stabilizers, buffers and salts to successfully purify and formulate your biomolecules. Specifically developed for high-risk applications, they are low in bioburden and endotoxins.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
应用
Arginine hydrochloride has several applications in biopharma manufacturing such as an additive for protein refolding, aggregate suppression and buffer for chromatography.
Due to its low microbial and endotoxin limits, L-Arginine monohydrochloride Emprove® Expert is suitable for high-risk applications.
Due to its low microbial and endotoxin limits, L-Arginine monohydrochloride Emprove® Expert is suitable for high-risk applications.
生化/生理作用
一氧化氮合成酶的底物，可以转化为瓜氨酸和一氧化氮 (NO)。通过与一氧化氮相关的机理诱导胰岛素释放。
法律信息
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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