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Merck
CN
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主要文件

1.08307

SAFC

高纯度三(羟甲基)胺基甲烷(氨基丁三醇)

(Trometamol) high purity, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JPC, USP

别名:

三(羟甲基)氨基甲烷, 2-氨基-2-(羟甲基)-1,3-丙二醇, THAM, Tris 碱, 氨基丁三醇

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About This Item

线性分子式:
NH2C(CH2OH)3
CAS Number:
分子量:
121.14
Beilstein:
741883
MDL编号:
UNSPSC代码:
12352209
EC索引号:
201-064-4

Agency

BP
ChP
JPC
Ph. Eur.
USP

质量水平

蒸汽压

0.0267 hPa ( 20 °C)

描述

EMPROVE® EXPERT Ph Eur,BP,JPC,USP,ACS

产品线

EMPROVE® EXPERT

表单

solid

特点

RNase and DNase free

pH值(酸碱度)

10.2-10.6 (20 °C, 6 g/L in H2O)

有效pH范围

7-9

pKa (25 °C)

8.1

沸点

219-220 °C/10 mmHg (lit.)
219-220 °C/13.3 hPa

mp

167-172 °C (lit.)

密度

1.35 g/cm3 at 23 °C

应用

liquid formulation
pharmaceutical
semi-solid formulation

储存温度

no temp limit

SMILES字符串

NC(CO)(CO)CO

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

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一般描述

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Tris(hydroxymethyl)aminomethane (Trometamol) is a commonly used buffer component in biomolecule downstream chromatography steps as well as final liquid formulation.
Due to its low polyoxymethylene limits, Tris(hydroxymethyl)aminomethane (Trometamol) Emprove® Expert is suitable for use at elevated concentrations without risking precipitation. Also, low microbial and endotoxin limits facilitate the use of this product in high-risk applications.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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