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Merck
CN

1.16887

Fractogel EMD TMAE (S)

strong anion exchanger, suspension in 20% ethanol and 150 mM NaCl (20-40 µm)

别名:

Fractogel® EMD TMAE (S)

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UNSPSC Code:
41115711
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产品名称

Fractogel EMD TMAE (S), strong anion exchanger, suspension in 20% ethanol and 150 mM NaCl (20-40 µm)

ligand

(Trimethylammoniumethyl)

Quality Level

product line

Fractogel®

form

resin

parameter

8 bar max. pressure
80 cm/hr flow rate

matrix active group

methacrylate

capacity

100 mg binding capacity (BSA/mg of resin)

transition temp

flash point 35 °C (calculated)

density

1.430 g/cm3 at 20 °C

bulk density

1000 kg/m3

application(s)

gene therapy
recombinant protein
vaccine development

separation technique

anion exchange
strong anion exchange

storage temp.

2-30°C

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Analysis Note

Appearance: Milky turbid suspension, free from impurities (foreign particles)
Microscopic evaluation: Uniform spherical particles, no agglomerates, no fines
Extractable matter (water): ≤ 0.03 %
Ce content: ≤ 1 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 5.0 bar
Particle size (d10): 20 - 28 µm
Particle size (d50): 24 - 34 µm
Particle size (d90): 28 - 38 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (bovine serum albumin): 80 - 120 mg/ml
Functional test (b:a): ≤ 0.1
Functional Test: Seperation of conalbumin and human serum albumin

Features and Benefits

Fractogel® EMD TMAE (S) (20-40 µm particle size) enables:

High protein loading conditions resulting in good selectivity and resolution with the tentacle technology
  • Excellent binding to large viruses at increased loading
  • Homogenous binding with high selectivity and purity
  • Reduce operating costs and resin replacement with enduring durability - allowing for multiple cycles of column regeneration and sanitization
  • Compatibility with 2.5 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl storage solution

General description

Stron anion exchange Fractogel® resin with small particle size, featuring the tentacle technology with a trimethylammoniumethyl functional group, for purification of acidic and neutral proteins and peptides from multiple sources, DNA and virus removal, plasmid isolation, vaccine purification, and more

Packaging

  • 1.16887.0100: Fractogel® EMD TMAE (S) Resin 100ml
  • 1.16887.0010: Fractogel® EMD TMAE (S) Resin 10ml
  • 1.16887.0500: Fractogel® EMD TMAE (S) Resin 500ml
  • 1.16887.5000: Fractogel® EMD TMAE (S) Resin 5L

Plastic bottle

Legal Information

FRACTOGEL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Flame

signalword

Warning

hcodes

Hazard Classifications

Flam. Liq. 3

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

95.0 °F

flash_point_c

35 °C


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