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Merck
CN

1.37162

D -甘露醇

EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

别名:

甘露糖醇

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关于此项目

经验公式(希尔记法):
C6H14O6
化学文摘社编号:
分子量:
182.17
UNSPSC Code:
12352201
Beilstein/REAXYS Number:
1721898
MDL number:
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Quality Level

agency

BP, ChP, JP, Ph. Eur., USP

product line

EMPROVE® EXPERT

form

solid

autoignition temp.

410 °C

impurities

low in endotoxins

pH

5.0-6.5 (120 °C, 182 g/L)

bp

290-295 °C/4.67 hPa

mp

166-169 °C, 167-170 °C (lit.)

solubility

213 g/L

application(s)

liquid formulation
ophthalmics
parenterals
pharma/biopharma processes

storage temp.

2-25°C

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-KVTDHHQDSA-N

General description

Chemicals play an important role in the stabilization of a biologic drug during its manufacturing and formulation process – for instance, by preventing aggregation. We offer a wide range of high-quality stabilizers, buffers and salts to successfully purify and formulate your biomolecules. Specifically developed for high-risk applications, they are low in bioburden and endotoxins. As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Mannitol is a sugar alcohol which is used widely in biomolecule formulations as a stabilizer, bulking agent, and lyoprotecting agent, especially in lyophilization. Due to its low microbial and endotoxin limits, D(-)-Mannitol Emprove® Expert is especially suitable for high-risk applications.

Biochem/physiol Actions

一种糖醇类甜味剂。 用于甜味抑制研究。

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany


存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Learn more on mAb subcutaneous or intravenous formulation, and the relevant associated products, including excipients.





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