InChI key
UREBDLICKHMUKA-CXSFZGCWSA-N
InChI
1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
SMILES string
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
grade
pharmaceutical primary standard
API family
dexamethasone
form
solid
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
BP
Gene Information
human ... NR3C1(2908)
application(s)
pharmaceutical
pharmaceutical small molecule
format
neat
storage temp.
2-8°C
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General description
该产品在交付时提供并符合现行药典规定。随附的本产品的所有支持信息,包括SDS和任何产品信息彩页,均遵照现行药典许可而编制和发布。
更多信息和支持,请见现行药典网站。
更多信息和支持,请见现行药典网站。
Application
地塞米松BP参考标准品设计用于USP规定的指定质量测试和检测。
也用于专著,例如:妥布霉素和地塞米松滴眼液、悬浮液 地塞米松磷酸钠口服溶液 氢化可的松琥珀酸钠注射液 强的松片 地塞米松滴眼液、悬浮液 地塞米松磷酸钠滴眼液、溶液 地塞米松和新霉素耳喷雾剂 倍他米松片 地塞米松片
也用于专著,例如:
Biochem/physiol Actions
糖皮质激素抗炎剂
糖皮质激素抗炎剂。 调节T细胞生存、生长和分化。抑制一氧化氮合酶活性的诱导。
Other Notes
可能适用相应的销售限制。
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
A Keith Stewart et al.
The New England journal of medicine, 372(2), 142-152 (2014-12-09)
Lenalidomide plus dexamethasone is a reference treatment for relapsed multiple myeloma. The combination of the proteasome inhibitor carfilzomib with lenalidomide and dexamethasone has shown efficacy in a phase 1 and 2 study in relapsed multiple myeloma. We randomly assigned 792
Wei Zheng et al.
Genes & development, 28(14), 1592-1603 (2014-07-18)
Primitive lymphatic vessels are remodeled into functionally specialized initial and collecting lymphatics during development. Lymphatic endothelial cell (LEC) junctions in initial lymphatics transform from a zipper-like to a button-like pattern during collecting vessel development, but what regulates this process is
Alexandre Denoyer et al.
Ophthalmology, 122(4), 669-676 (2014-12-03)
To compare small incision lenticule extraction (SMILE) versus LASIK for post-refractive dry eye disease. Prospective, comparative, nonrandomized clinical study. Thirty patients scheduled for bilateral myopic SMILE and 30 age-, sex-, and refraction-matched patients scheduled for bilateral myopic LASIK were enrolled
Li Wang et al.
Stem cells and development, 23(20), 2482-2489 (2014-05-20)
The objective of this study was to evaluate the safety and efficacy of allogeneic bone marrow mesenchymal stromal/stem cell transplantation (BM-MSCT) for patients with ursodeoxycholic acid (UDCA)-resistant primary biliary cirrhosis (PBC). Ten patients were enrolled in this trial of BM-MSCT.
D Rhebergen et al.
Psychoneuroendocrinology, 51, 341-350 (2014-12-03)
Altered functioning of the hypothalamic-pituitary-adrenal axis (HPA-axis) has been associated with depression, but findings have been inconsistent. Among older depressed persons, both hyperactivity and hypo-activity of the HPA-axis were demonstrated. However, most studies were population-based studies, with single cortisol measurements
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