PHR1006
山梨醇
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
D -山梨醇, D-山梨糖醇
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关于此项目
经验公式（希尔记法）:
C6H14O6
化学文摘社编号:
分子量:
182.17
UNSPSC Code:
12352201
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-061-5
Beilstein/REAXYS Number:
1721899
MDL number:
InChI key
FBPFZTCFMRRESA-JGWLITMVSA-N
InChI
1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1
SMILES string
OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. S100000, traceable to USP 1617000
vapor density
<1 (vs air)
vapor pressure
<0.1 mmHg ( 25 °C)
API family
sorbitol
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
98-100 °C (lit.)
application(s)
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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General description
用于质量控制的经认证的药物二级标准为制药实验室和制造商提供了一种方便且具有成本效益的内部工作标准品替代品。
Application
山梨醇可用作药物参考标准品，用于通过高效液相色谱法测定药物配方中的分析物。
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他标定应用。
采用气相色谱法 (GLC) 定量测定玉米糖和玉米糖浆中的 D-葡萄糖时，山梨醇可作为内标物。
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Other Notes
如需查看该材料的检验报告示例，请在下面的栏位中输入 LRAB7795。这只是一个示例证书，可能不是您收到的批次。
该认证标准物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Use of sorbitol as internal standard in determination of D-glucose by gas liquid chromatography
Alexander.J.R and Garbutt.T.J
Analytical Chemistry, 37, 303-305 (1965)
An isocratic HPLC method for the determination of sorbitol and glycerol in pharmaceutical formulations
Simonzadeh N and Ronsen B
Journal of Chromatographic Science, 50(7), 644-647 (2012)
Determination of nimesulide in pharmaceutical dosage forms by second order derivative UV spectrophotometry
Altinoz S and Dursun OO
Journal of Pharmaceutical and Biomedical Analysis, 22(1), 175-182 (2000)
Reddy Ranjith K Sama et al.
Journal of cellular physiology, 228(11), 2222-2231 (2013-04-30)
FUsed in Sarcoma/Translocated in LipoSarcoma (FUS/TLS or FUS) has been linked to several biological processes involving DNA and RNA processing, and has been associated with multiple diseases, including myxoid liposarcoma and amyotrophic lateral sclerosis (ALS). ALS-associated mutations cause FUS to
G Molino et al.
The Journal of laboratory and clinical medicine, 131(5), 393-405 (1998-05-30)
D-Sorbitol (SOR) is safe, is easy to measure, and has an exceptionally high extraction ratio in the normal liver of 0.93+/-0.05 (mean+/-SD). Together with the general interest in hepatic hemodynamics, these facts motivated us to review the usefulness of this
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