PHR1025
乳糖(无水)
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
乳糖
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关于此项目
经验公式（希尔记法）:
C12H22O11
化学文摘社编号:
分子量:
342.30
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-559-2
Beilstein/REAXYS Number:
93796
MDL number:
InChI
1S/C12H22O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h1,4-12,14-21H,2-3H2/t4-,5+,6+,7+,8-,9-,10+,11+,12-/m0/s1
InChI key
DKXNBNKWCZZMJT-JVCRWLNRSA-N
SMILES string
OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C=O
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. A1206000, traceable to USP 1356676
API family
lactose
CofA
current certificate can be downloaded
analyte chemical class(es)
oligosaccharides
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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General description
用于质量控制的制药二级标准，为制药实验室和制造商提供了一种方便且具有成本效益的替代方案，可用于制定内部工作标准品。
Application
无水乳糖可用作药物参考标准品，通过色谱技术测定药物制剂中的分析物。
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Other Notes
若要查看此材料的分析证书示例，请在下面的区域中输入 LRAB2931。这只是一个示例证书，可能与您收到批次的产品无关。
该认证参考物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
The influence of carrier and drug morphology on drug delivery from dry powder formulations
Larhrib H, et al.
International Journal of Pharmaceutics, 257(1-2), 283-296 (2003)
Assessment of feasibility of Maillard reaction between baclofen and lactose by liquid chromatography and tandem mass spectrometry, application to pre formulation studies
Monajjemzadeh F, et al.
Aaps Pharmscitech, 10(2), 649-659 (2009)
Compatibility studies of acyclovir and lactose in physical mixtures and commercial tablets
Monajjemzadeh F, et al.
European Journal of Pharmaceutics and Biopharmaceutics, 73(3), 404-413 (2009)
Martin Andreas Wälti et al.
Journal of molecular biology, 379(1), 146-159 (2008-04-29)
Recent advances in genome sequencing efforts have revealed an abundance of novel putative lectins. Among these, many galectin-related proteins, characterized by many conserved residues but intriguingly lacking critical amino acids, have been found in all corners of the eukaryotic superkingdom.
Thao T Le et al.
Food chemistry, 141(2), 1203-1210 (2013-06-26)
Lactosylation in stored milk powder was quantified by multiple reaction monitoring (MRM), a mass spectrometry-based quantification method. The MRM method was developed from a knowledge of peptide fragmentation. The neutral losses of 162Da (cleavage of galactose) and 216Da (the formation
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