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文件

PHR1101

L-赖氨酸单盐酸盐

Name: <SC>L</SC>-赖氨酸 单盐酸盐
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

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别名:

(S)-2,6-二氨基己酸单盐酸盐

线性分子式:

H₂N(CH₂)₄CH(NH₂)CO₂H·HCl

CAS号:

657-27-2

分子量:

182.65

Beilstein:

3563889

EC 号:

211-519-9

MDL编号:

MFCD00064564

PubChem化学物质编号:

329823123

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to Ph. Eur. L0900000
traceable to USP 1372005

API family

lysine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

263 °C (dec.) (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES string

OC([C@@H](N)CCCCN)=O.[H]Cl

InChI

1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1

InChI key

BVHLGVCQOALMSV-JEDNCBNOSA-N

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一般描述

药物二级标准品CRM，为制药行业QC实验室及生产质量控制和研发，提供了一种方便、高性价比且符合相关法规的替代方案。L-赖氨酸是必需氨基酸，人体无法产生，必需通过食物补充。人们认为L-赖氨酸可以预防骨质疏松，这是血管钙化的一个特征。

应用

这些二级标准品是经认证过的有证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

分析说明

这些二级标准品可溯源到USP、EP（PhEur）或BP一级标准品。

其他说明

该认证参考物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

附注

要查看此物质的示例分析证书，请在下面的空格中输入 LRAA7137。这只是一个示例证书，可能与您收到的批次不符。

储存分类代码

13 - Non Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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如果您查询到的批号含有填充代码（例如05427ES-021），请输入去除填充代码-021的批号：05427ES。
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未找到您寻找的产品？

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索取COA

PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum.

Lubin Jiang et al.

Nature, 499(7457), 223-227 (2013-07-05)

The variant antigen Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), which is expressed on the surface of P. falciparum-infected red blood cells, is a critical virulence factor for malaria. Each parasite has 60 antigenically distinct var genes that each code

A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins.

Guntur Fibriansah et al.

Nature communications, 6, 6341-6341 (2015-02-24)

Dengue virus (DENV) infects ~400 million people annually. There is no licensed vaccine or therapeutic drug. Only a small fraction of the total DENV-specific antibodies in a naturally occurring dengue infection consists of highly neutralizing antibodies. Here we show that

A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection.

Haig A Eskandarian et al.

Science (New York, N.Y.), 341(6145), 1238858-1238858 (2013-08-03)

Pathogens dramatically affect host cell transcription programs for their own profit during infection, but in most cases, the underlying mechanisms remain elusive. We found that during infection with the bacterium Listeria monocytogenes, the host deacetylase sirtuin 2 (SIRT2) translocates to

Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes.

Alexander Leitner et al.

Proceedings of the National Academy of Sciences of the United States of America, 111(26), 9455-9460 (2014-06-19)

The study of proteins and protein complexes using chemical cross-linking followed by the MS identification of the cross-linked peptides has found increasingly widespread use in recent years. Thus far, such analyses have used almost exclusively homobifunctional, amine-reactive cross-linking reagents. Here

A lysine-rich membrane-associated PHISTb protein involved in alteration of the cytoadhesive properties of Plasmodium falciparum-infected red blood cells.

Nicholas I Proellocks et al.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(7), 3103-3113 (2014-04-08)

The genomes of malaria parasites (Plasmodium spp.) contain a family of genes encoding proteins with a Plasmodium helical interspersed subtelomeric (PHIST) domain, most of which are predicted to be exported into the parasite-infected human red blood cell (iRBC). Here, using

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L-赖氨酸 单盐酸盐