PHR1449
水杨酰胺
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
水杨酰胺, 2-羟基苯甲酰胺
等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to USP 1608000
API类
salicylamide
CofA
current certificate can be downloaded
包装
pkg of 1 g
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
140-144 °C (lit.)
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-30°C
SMILES字符串
NC(=O)c1ccccc1O
InChI
1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
InChI key
SKZKKFZAGNVIMN-UHFFFAOYSA-N
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一般描述
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards. Salicylamide is an antipyretic and analgesic, frequently prescribed in combination with other related drugs.
应用
Salicylamide may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrofluorimetry, spectrophotometry and high-performance thin layer chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析说明
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA2826 in the slot below. This is an example certificate only and may not be the lot that you receive.
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Spectrophotometric Determination of Salicylamide and Paracetamol in Biological Samples and Pharmaceutical Formulations by a Differential Kinetic Method.
Afkhami A, et al.
Acta Chimica Slovenica, 53(3), 619-624 (2006)
Determination of salicylamide in pharmaceutical tablets by high-performance thin-layer chromatography with ultraviolet absorption densitometry.
Sullivan C and Sherma J
Acta Chromatographica , 16(3), 153-163 (2006)
A simple solid phase spectrofluorimetric method combined with flow analysis for the rapid determination of salicylamide and salicylic acid in pharmaceutical samples.
Medina AR, et al.
Fresenius Journal of Analytical Chemistry, 365(7), 619-624 (1999)
Saura C Sahu et al.
Journal of applied toxicology : JAT, 34(11), 1155-1166 (2014-02-14)
The use of silver nanoparticles in food, food contact materials, dietary supplements and cosmetics has increased significantly owing to their antibacterial and antifungal properties. As a consequence, the need for validated rapid screening methods to assess their toxicity is necessary
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