PHR1449
水杨酰胺
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
水杨酰胺, 2-羟基苯甲酰胺
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线性分子式:
2-(HO)C6H4CONH2
化学文摘社编号:
分子量:
137.14
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-609-3
Beilstein/REAXYS Number:
742439
MDL number:
产品名称
水杨酰胺, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
SKZKKFZAGNVIMN-UHFFFAOYSA-N
InChI
1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
SMILES string
NC(=O)c1ccccc1O
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1608000
API family
salicylamide
CofA
current certificate can be downloaded
packaging
pkg of 1 g
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
140-144 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Application
Salicylamide may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrofluorimetry, spectrophotometry and high-performance thin layer chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards. Salicylamide is an antipyretic and analgesic, frequently prescribed in combination with other related drugs.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA2826 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
A simple solid phase spectrofluorimetric method combined with flow analysis for the rapid determination of salicylamide and salicylic acid in pharmaceutical samples.
Medina AR, et al.
Fresenius Journal of Analytical Chemistry, 365(7), 619-624 (1999)
Spectrophotometric Determination of Salicylamide and Paracetamol in Biological Samples and Pharmaceutical Formulations by a Differential Kinetic Method.
Afkhami A, et al.
Acta Chimica Slovenica, 53(3), 619-624 (2006)
Determination of salicylamide in pharmaceutical tablets by high-performance thin-layer chromatography with ultraviolet absorption densitometry.
Sullivan C and Sherma J
Acta Chromatographica , 16(3), 153-163 (2006)
Saura C Sahu et al.
Journal of applied toxicology : JAT, 34(11), 1155-1166 (2014-02-14)
The use of silver nanoparticles in food, food contact materials, dietary supplements and cosmetics has increased significantly owing to their antibacterial and antifungal properties. As a consequence, the need for validated rapid screening methods to assess their toxicity is necessary
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默克Supelco®标准物质不断推出或更新满足海关及法规要求的标准物质。每年我们约有上百种的新CRM或标准物质上市，在此我们尽可能多的列出满足海关及法规要求的标准物质。
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