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Merck
CN

PHR1610

Supelco

乙琥红霉素

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

Erythromycin ethyl succinate

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关于此项目

经验公式（希尔记法）:
C43H75NO16
化学文摘社编号:
1264-62-6
分子量:
862.05
EC 号:
215-033-8
MDL编号:
MFCD00084692
UNSPSC代码:
41116107
PubChem化学物质编号:
329823507
NACRES:
NA.24

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等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to USP 1245008

API类

erythromycin

CofA

current certificate can be downloaded

包装

pkg of 250 mg

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

CCOC(=O)CCC(=O)OC1C(CC(C)OC1OC2C(C)C(OC3CC(C)(OC)C(O)C(C)O3)C(C)C(=O)OC(CC)C(C)(O)C(O)C(C)C(=O)C(C)CC2(C)O)N(C)C

InChI

1S/C43H75NO16/c1-15-29-43(11,52)36(48)24(5)33(47)22(3)20-41(9,51)38(25(6)34(26(7)39(50)57-29)59-32-21-42(10,53-14)37(49)27(8)56-32)60-40-35(28(44(12)13)19-23(4)55-40)58-31(46)18-17-30(45)54-16-2/h22-29,32,34-38,40,48-49,51-52H,15-21H2,1-14H3

InChI key

NSYZCCDSJNWWJL-UHFFFAOYSA-N

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相关类别

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Erythromycin Ethylsuccinate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA4726 in the slot below. This is an example certificate only and may not be the lot that you receive.

象形图

Health hazard
GHS08

警示用语：

Danger

危险声明

H317,H334

预防措施声明

P261 - P280 - P342 + P311

危险分类

Resp. Sens. 1 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Determination of erythromycin and related substances in enteric-coated tablet formulations by reversed-phase liquid chromatography.
Wardrop J, et al.
Journal of Pharmaceutical Sciences, 89(9), 1097-1105 (2000)
High performance thin layer chromatographic determination of erythromycin in pharmaceutical preparations.
Liawruangrath B and Liawruangrath S
Chromatographia, 54(5-6), 405-408 (2001)
Development of a stability-indicating high performance liquid chromatography method for assay of erythromycin ethylsuccinate in powder for oral suspension dosage form.
Kamarei F, et al.
Arabian Journal of Chemistry, 7(6), 1079-1085 (2014)

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