跳转至内容
Merck
CN

PHR1716

Capreomycin Sulfate

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

Capreomycin sulfate salt

登录 查看组织和合同定价。

选择尺寸

关于此项目

化学文摘社编号:
1405-37-4
UNSPSC Code:
41116107
EC Number:
215-776-8
NACRES:
NA.24

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

SMILES string

[S](=O)(=O)(O)O.N1C(CCNC1=N)C2NC(=O)\C(=C\NC(=O)N)\NC(=O)C(NC(=O)C(NC(=O)C(CNC2=O)N)CO)CNC(=O)CC(N)CCCN

InChI key

AJQVUIHGEOLMDY-SOCRLDLMSA-N

InChI

1S/C25H44N14O8.H2O4S/c26-4-1-2-11(27)6-17(41)32-8-14-20(43)35-15(9-34-25(30)47)21(44)39-18(13-3-5-31-24(29)38-13)23(46)33-7-12(28)19(42)37-16(10-40)22(45)36-14;1-5(2,3)4/h9,11-14,16,18,40H,1-8,10,26-28H2,(H,32,41)(H,33,46)(H,35,43)(H,36,45)(H,37,42)(H,39,44)(H3,29,31,38)(H3,30,34,47);(H2,1,2,3,4)/b15-9-;

grade

certified reference material, pharmaceutical secondary standard

agency

USP 1091006

API family

capreomycin

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

300

正在寻找类似产品? 访问 产品对比指南

相关类别

General description

Capreomycin sulfate is a disulfate salt of the polypeptide antibiotic drug, capreomycin, that is administered either parenterally or in the form of aerosols. It is generally used against multidrug-resistant tuberculosis (MDR-TB).
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Capreomycin sulfate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3042 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品
此项目有

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Development and validation of a liquid chromatographic method for the analysis of capreomycin sulfate and its related substances
Mallampati S, et al.
Journal of Chromatography A, 1216(12), 2449-2455 (2009)
Isolation and identification of four major impurities in capreomycin sulfate
Liu G, et al.
Journal of Chromatography A, 1571(12), 155-164 (2018)
Inhaled large porous particles of capreomycin for treatment of tuberculosis in a guinea pig model
Garcia-Contreras L, et al.
Antimicrobial Agents and Chemotherapy, 51(8), 2830-2836 (2007)

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持