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PHR1766

依普菌素

Name: 依普菌素
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

依普菌素, (4″R)-4″-(乙酰氨基)-4″-脱氧-阿维菌素 B₁

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关于此项目

经验公式（希尔记法）:

C₅₀H₇₅NO₁₄

化学文摘社编号:

123997-26-2

分子量:

914.13

NACRES:

NA.24

UNSPSC Code:

41116107

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属性

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1237752

API family

eprinomectin

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

-10 to -25°C

SMILES string

C[C@H]1[C@H](NC(C)=O)[C@@H](OC)C[C@H](O[C@H]2[C@H](C)O[C@@H](O[C@H](/C(C)=C/C[C@]3([H])C[C@H]4C[C@@]5(O[C@@]([R])([H])[C@@H](C)C=C5)O3)[C@@H](C)/C=C/C=C(CO6)/[C@@]([C@@]6([H])[C@H](O)C(C)=C7)(O)[C@]7([H])C(O4)=O)C[C@@H]2OC)O1.CCC.CCCC

InChI

1S/C49H73NO14/c1-25(2)43-28(5)17-18-48(64-43)23-35-20-34(63-48)16-15-27(4)44(26(3)13-12-14-33-24-57-46-42(52)29(6)19-36(47(53)60-35)49(33,46)54)61-40-22-38(56-11)45(31(8)59-40)62-39-21-37(55-10)41(30(7)58-39)50-32(9)51/h12-15,17-19,25-26,28,30-31,34-46,52,54H,16,20-24H2,1-11H3,(H,50,51)/b13-12-,27-15-,33-14-/t26-,28-,30-,31-,34+,35-,36-,37+,38-,39-,40-,41+,42+,43+,44-,45+,46+,48+,49+/m0/s1

InChI key

WPNHOHPRXXCPRA-TVXIRPTOSA-N

说明

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Eprinomectin is a veterinary endectocide, which belongs to the class of macrocyclic lactones. It is commonly produced through fermentation by soil-dwelling Streptomyces.

Application

Eprinomectin may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug, in beef liver and injectable drug products and pharmaceutical formulations by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC3732 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

GHS06,GHS08,GHS09

signalword

Danger

hcodes

H301,H361,H410

pcodes

P201 - P273 - P301 + P310 + P330

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Pesticide use and associated morbidity and mortality in veterinary medicine

Hayes' Handbook of Pesticide Toxicology, 285-301 (2010)

RP-HPLC determination of eprinomectin [J]

Suying CI, et al

Chinese Journal of Pharmaceutical Analysis, 6, 285-301 (2010)

Eprinomectin

USP42/NF37

United States Pharmacopeia/National Formulary, 42(4), 1627-1627 (2019)

全球贸易项目编号

货号	GTIN
PHR1766-1G	04061835080038