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Merck
CN

PHR2716

咪喹莫特

Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 500 mg

别名:

1-(2-甲基丙基)-1 H -咪唑 [4,5- c ] 喹啉-4-胺

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关于此项目

经验公式(希尔记法):
C14H16N4
化学文摘社编号:
分子量:
240.30
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
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产品名称

咪喹莫特, Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 500 mg

InChI

1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)

SMILES string

CC(C)Cn1cnc2c(N)nc3ccccc3c12

InChI key

DOUYETYNHWVLEO-UHFFFAOYSA-N

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1338313

API family

imiquimod

form

solid

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

application(s)

pharmaceutical small molecule

storage temp.

2-30°C

Quality Level

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Biochem/physiol Actions

咪喹莫特是半胱天冬酶 3 激活剂,可直接诱导半胱天冬酶 3 裂解为活性半胱天冬酶 3。咪喹莫特在体内 诱导基底细胞癌凋亡 。其抗肿瘤活性与诱导细胞凋亡有关。咪喹莫特具有抗血管生成、抗炎、抗病毒活性。咪喹莫特还可作为免疫应答调节剂,诱导多种细胞因子和趋化因子的分泌。
咪喹莫特是半胱天冬酶 3 激活剂,可直接诱导半胱天冬酶 3 裂解为活性半胱天冬酶 3。咪喹莫特在体内可诱导细胞凋亡 ,并作为一种免疫调节剂,具有抗病毒和抗炎特性。

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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