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经验公式(希尔记法):
C14H16N4
化学文摘社编号:
分子量:
240.30
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
产品名称
咪喹莫特, Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 500 mg
InChI
1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)
SMILES string
CC(C)Cn1cnc2c(N)nc3ccccc3c12
InChI key
DOUYETYNHWVLEO-UHFFFAOYSA-N
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1338313
API family
imiquimod
form
solid
CofA
current certificate can be downloaded
packaging
pkg of 500 mg
application(s)
pharmaceutical small molecule
storage temp.
2-30°C
Quality Level
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Biochem/physiol Actions
咪喹莫特是半胱天冬酶 3 激活剂,可直接诱导半胱天冬酶 3 裂解为活性半胱天冬酶 3。咪喹莫特在体内 诱导基底细胞癌凋亡 。其抗肿瘤活性与诱导细胞凋亡有关。咪喹莫特具有抗血管生成、抗炎、抗病毒活性。咪喹莫特还可作为免疫应答调节剂,诱导多种细胞因子和趋化因子的分泌。
咪喹莫特是半胱天冬酶 3 激活剂,可直接诱导半胱天冬酶 3 裂解为活性半胱天冬酶 3。咪喹莫特在体内可诱导细胞凋亡 ,并作为一种免疫调节剂,具有抗病毒和抗炎特性。
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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