A0879
N-（4-氨基苯甲酰基）-L-谷氨酸
≥98% (TLC)
别名:
N-（对氨基苯甲酰基）谷氨酸
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关于此项目
经验公式（希尔记法）:
C12H14N2O5
化学文摘社编号:
分子量:
266.25
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
224-261-7
MDL number:
Beilstein/REAXYS Number:
2816320
产品名称
N-（4-氨基苯甲酰基）-L-谷氨酸, ≥98% (TLC)
InChI
1S/C12H14N2O5/c13-8-3-1-7(2-4-8)11(17)14-9(12(18)19)5-6-10(15)16/h1-4,9H,5-6,13H2,(H,14,17)(H,15,16)(H,18,19)/t9-/m0/s1
InChI key
GADGMZDHLQLZRI-VIFPVBQESA-N
SMILES string
Nc1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
assay
≥98% (TLC)
form
powder
color
off-white to beige
mp
175 °C (dec.)
application(s)
detection
peptide synthesis
storage temp.
−20°C
Quality Level
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Application
N-（4-氨基苯甲酰基）-L-谷氨酸（ABG）可用作一种强紫外吸收标签，用于寡糖的衍生化，衍生化的寡糖更容易在毛细管区带电泳等分析方法中检测到。
Biochem/physiol Actions
N-对氨基苯甲酰基）-L-谷氨酸是一种叶酸分解代谢物，其可被具有对氨基苯甲酰基-谷氨酸水解酶的细菌对氨基苯甲酸营养缺陷型代谢。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
J Plocek et al.
Journal of chromatography. A, 757(1-2), 215-223 (1997-01-03)
A charged and strongly UV-absorbing tag, N-(4-aminobenzoyl)-L-glutamic acid) (ABG), was coupled to oligosaccharides by reductive amination under mild conditions. The effectiveness of ABG as a derivatization agent is shown through the separation of isomaltooligosaccharides from a dextran hydrolysate. The minimum
Regina S Scurachio et al.
Photochemistry and photobiology, 87(4), 840-845 (2011-03-08)
Folate is shown to react with singlet-excited state of riboflavin in a diffusion controlled reaction and with triplet-excited state of riboflavin in a somewhat slower reaction with (3)k(q) = 4.8 × 10(8) L mol(-1) s(-1) in aqueous phosphate buffer at
M Laura Dántola et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 9(12), 1604-1612 (2010-10-06)
Folic acid, or pteroyl-l-glutamic acid (PteGlu), is a precursor of coenzymes involved in the metabolism of nucleotides and amino acids. PteGlu is composed of three moieties: a 6-methylpterin (Mep) residue, a p-aminobenzoic acid (PABA) residue, and a glutamic acid (Glu)
Densitometric determination of impurities in drugs: Part IV. Determination of N-(4-aminobenzoyl)-L-glutamic acid in preparations of folic acid.
J Krzek et al.
Journal of pharmaceutical and biomedical analysis, 21(2), 451-457 (2000-03-07)
Judith M Wolfe et al.
The American journal of clinical nutrition, 77(4), 919-923 (2003-03-29)
The major route of folate turnover is by catabolic cleavage of the C9-N10 bond producing p-aminobenzoylglutamate (pABG) and its primary excretory form, p-acetamidobenzoylglutamate (ApABG). We hypothesize that total pABG (ApABG + pABG) excretion parallels both the mass of body folate
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