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Merck
CN

1154569

USP

β-环糊精

United States Pharmacopeia (USP) Reference Standard

别名:

Schardinger β-Dextrin, 环七淀粉, 环糊精, 环麦芽七糖

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关于此项目

经验公式（希尔记法）:
C42H70O35
化学文摘社编号:
7585-39-9
分子量:
1134.98
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329749476
MDL number:
MFCD00078139
Beilstein/REAXYS Number:
78623

主要文件

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InChI key

WHGYBXFWUBPSRW-FOUAGVGXSA-N

InChI

1S/C42H70O35/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-63H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m1/s1

SMILES string

OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]8[C@H](O)[C@@H](O)[C@H](O[C@@H]8CO)O[C@H]1[C@H](O)[C@H]2O

biological source

plant

grade

pharmaceutical primary standard

optical activity

[α]20/D +162±3°, c = 1.5% in H2O

analyte chemical class(es)

oligosaccharides

manufacturer/tradename

USP

mp

290-300 °C (dec.) (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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相关类别

General description

Betadex is a nonreducing cyclic compound composed of seven alpha-(1–4) linked d-glucopyranosyl units.

Application

Beta Cyclodextrin USP reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare standard and system suitability solution for the assay and impurity analysis by using liquid chromatography coupled with Refractive index detector according to the below monographs of United States Pharmacopeia (USP) :

  • Betadex
  • Alfadex

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.
USP issued SDS can be found here.

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Betadex
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 31(1) (2020)
Alfadex
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 34(1) (2020)
Nuclear magnetic resonance methods for high molecular weight proteins: a study involving a complex of maltose binding protein and beta-cyclodextrin.
L E Kay
Methods in enzymology, 339, 174-203 (2001-07-21)
H Chen et al.
Se pu = Chinese journal of chromatography, 17(6), 533-538 (2003-01-30)
A review of beta-cyclodextrin bonded stationary phases in chiral liquid chromatography is given, focusing on design and synthesis of beta-cyclodextrin bonded chiral stationary phases. Fifty-three references are presented in this paper.
Omair Aleem et al.
Journal of pharmaceutical and biomedical analysis, 47(3), 535-540 (2008-03-28)
The solid-state properties, dissolution profile and antimicrobial activity of inclusion complexes of cefdinir (CEF) with beta-cyclodextrin (betaCD) and hydroxypropyl beta-cyclodextrin (HPbetaCD) were investigated. The phase solubility profiles of cefdinir with betaCD and HPbetaCD were classified as A(L)-type, which indicates the
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