跳转至内容
Merck
CN

1242000

USP

红霉素

United States Pharmacopeia (USP) Reference Standard

登录查看公司和协议定价

选择尺寸

关于此项目

经验公式（希尔记法）:
C37H67NO13
化学文摘社编号:
114-07-8
分子量:
733.93
Beilstein:
75279
MDL编号:
MFCD00084654
UNSPSC代码:
41116107
PubChem化学物质编号:
329749382
NACRES:
NA.24

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

等级

pharmaceutical primary standard

API类

erythromycin

表单

solid

制造商/商品名称

USP

应用

USP Biologics
pharmaceutical (small molecule)

包装形式

neat

储存温度

−20°C

SMILES字符串

CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O

InChI

1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1

InChI key

ULGZDMOVFRHVEP-RWJQBGPGSA-N

正在寻找类似产品? 访问 产品对比指南

相关类别

一般描述

Erythromycin is a macrolide antibiotic produced by Saccharopolyspora erythraea, acting by inhibition of protein synthesis at the 50S ribosomal subunit. It is used to treat a variety of infections caused by susceptible organisms. The USP standard provides quality benchmarks for identification, assay, and dissolution studies in erythromycin formulations.

The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

应用

Erythromycin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Erythromycin Stearate
  • Erythromycin Ethylsuccinate
  • Erythromycin Lactobionate for Injection
  • Erythromycin Ointment
  • Erythromycin Pledgets
  • Erythromycin Injection

生化/生理作用

作用机制: 红霉素通过在转肽步骤中抑制延伸起作用，特别是通过结合细菌70S rRNA复合物的50S亚单位来抑制氨酰从A位点到P位点的易位。

抗菌谱：该产品可以抗革兰氏阴性和革兰氏阳性细菌。

制备说明

This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light.

其他说明

Technical Article available
This product is part of the USP Biologics program.

法律信息

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

免责声明

This product is stable in solution at 37°C for 3 days. Stock solutions should be stored at 2-8°C.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助，请联系 客户支持

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Erythromycin Ophthalmic Ointment
USP43-NF38 - 1689:United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(5) (2017)
Erythromycin Pledgets
USP43-NF38 - 1690:United States Pharmacopeia and National Formulary
United States Pharmacopeia, 34(5) (2013)
Erythromycin Delayed-Release Tablets
USP43-NF38 - 1691:United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3) (2023)
Erythromycin
USP43-NF38 - 1683:United States Pharmacopeia and National Formulary
United States Pharmacopeia, 48(1) (2020)
Erythromycin Topical Solution
USP43-NF38 - 1690:United States Pharmacopeia and National Formulary
United States Pharmacopeia (2013)
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持