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Merck
CN

1500003

USP

Paromomycin sulfate

United States Pharmacopeia (USP) Reference Standard

别名:

Paromomycin sulfate salt, Aminosidine sulfate

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关于此项目

经验公式（希尔记法）:
C23H45N5O14 · xH2SO4
化学文摘社编号:
1263-89-4
分子量:
615.63 (free base basis)
MDL number:
MFCD29505371
UNSPSC Code:
41116107
NACRES:
NA.24

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SMILES string

[S](=O)(=O)(O)O.N[C@H]1[C@H](O[C@H]([C@H]([C@@H]1O)O)CN)O[C@@H]2[C@H](OC([C@@H]2O)O[C@@H]3[C@H]([C@@H](C[C@@H](C3O[C@H]4O[C@@H]([C@H]([C@@H]([C@H]4N)O)O)CO)N)N)O)CO

InChI

1S/C23H45N5O14.H2O4S/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22;1-5(2,3)4/h5-23,29-36H,1-4,24-28H2;(H2,1,2,3,4)/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18?,19-,20-,21-,22-,23?;/m1./s1

InChI key

LJRDOKAZOAKLDU-UMIPPVEZSA-N

grade

pharmaceutical primary standard

API family

paromomycin

form

solid

manufacturer/tradename

USP

application(s)

USP Biologics
pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

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相关类别

General description

Paromomycin sulfate is an aminoglycoside antibiotic primarily used in the treatment of parasitic infections and certain bacterial infections. It inhibits protein synthesis at the 30S ribosomal subunit. The USP reference standard is employed in potency and identity assays.

The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Paromomycin Sulfate USP reference standard is used to prepare standard solutions for the identification and assay of paromomycin sulfate.
Also, for use with USP monographs such as:
  • Paromomycin Sulfate Capsules
  • Paromomycin Oral Solution

Other Notes

Sales restrictions may apply.
This product is part of the USP Biologics program.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Paromomycin Sulfate
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 3408-3408 (2013)

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