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Merck
CN

1500003

USP

Paromomycin sulfate

United States Pharmacopeia (USP) Reference Standard

别名:

Paromomycin sulfate salt, Aminosidine sulfate

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关于此项目

经验公式（希尔记法）:
C23H45N5O14 · xH2SO4
化学文摘社编号:
1263-89-4
分子量:
615.63 (free base basis)
MDL编号:
MFCD29505371
UNSPSC代码:
41116107
NACRES:
NA.24

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等级

pharmaceutical primary standard

API类

paromomycin

表单

solid

制造商/商品名称

USP

应用

USP Biologics
pharmaceutical (small molecule)

包装形式

neat

储存温度

−20°C

SMILES字符串

[S](=O)(=O)(O)O.N[C@H]1[C@H](O[C@H]([C@H]([C@@H]1O)O)CN)O[C@@H]2[C@H](OC([C@@H]2O)O[C@@H]3[C@H]([C@@H](C[C@@H](C3O[C@H]4O[C@@H]([C@H]([C@@H]([C@H]4N)O)O)CO)N)N)O)CO

InChI

1S/C23H45N5O14.H2O4S/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22;1-5(2,3)4/h5-23,29-36H,1-4,24-28H2;(H2,1,2,3,4)/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18?,19-,20-,21-,22-,23?;/m1./s1

InChI key

LJRDOKAZOAKLDU-UMIPPVEZSA-N

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相关类别

一般描述

Paromomycin sulfate is an aminoglycoside antibiotic primarily used in the treatment of parasitic infections and certain bacterial infections. It inhibits protein synthesis at the 30S ribosomal subunit. The USP reference standard is employed in potency and identity assays.

The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

应用

Paromomycin Sulfate USP reference standard is used to prepare standard solutions for the identification and assay of paromomycin sulfate.
Also, for use with USP monographs such as:
  • Paromomycin Sulfate Capsules
  • Paromomycin Oral Solution

其他说明

Sales restrictions may apply.
This product is part of the USP Biologics program.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Paromomycin Sulfate
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 3408-3408 (2013)

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