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Katie M Di Sebastiano et al.
The British journal of nutrition, 110(12), 2165-2172 (2013-06-12)
Glutamate is linked to the glycolytic process, particularly when co-ingested with carbohydrate, but its effects on glucose metabolism are poorly characterised. The present study aimed to (1) specifically examine the effects of carbohydrate administration on circulating glutamate concentrations and (2)
Nora Bourbia et al.
Neuroscience letters, 570, 26-31 (2014-04-22)
Amygdala has an important role in the processing of primary emotions, such as fear. Additionally, amygdala is involved in processing and modulation of pain. While the amygdala, particularly its central nucleus (CeA), has been shown to contribute to pain control
Signorá Peres Konrad et al.
Clinics (Sao Paulo, Brazil), 67(10), 1209-1214 (2012-10-17)
The aim of this study was to evaluate cardiovascular autonomic function in a rodent obesity model induced by monosodium glutamate injections during the first seven days of life. The animals were assigned to control (control, n = 10) and monosodium
B Sagalajev et al.
Behavioural brain research, 282, 14-24 (2015-01-06)
Amygdala is involved in processing of primary emotions and particularly its central nucleus (CeA) also in pain control. Here we studied mechanisms mediating the descending control of mechanical hypersensitivity by the CeA in rats with a peripheral neuropathy in the
Longsheng Xu et al.
Journal of neurophysiology, 108(11), 3024-3033 (2012-09-21)
The tyrosine kinases of Src family play an important role in the central sensitization following peripheral inflammation. However, whether the Src family in the arcuate nucleus (ARC) of mediobasal hypothalamus is involved in central sensitization remains unknown. The aim of
Monosodium L-glutamate-induced asthma.
Allen, David H., John Delohery, and Gary Baker.
The Journal of Allergy and Clinical Immunology, 80.4, 530-537 (1987)
Karen Ackroff et al.
Physiology & behavior, 107(2), 207-217 (2012-07-11)
Monosodium glutamate (MSG), the prototypical umami substance, is used as a flavor enhancer in many foods, but when presented alone is often only weakly attractive. Yet with experience mice will develop strong preferences for MSG solution over water. The present
Tingcai Cheng et al.
PloS one, 10(3), e0122837-e0122837 (2015-03-26)
The wild silkworm Bombyx mandarina is widely believed to be an ancestor of the domesticated silkworm, Bombyx mori. Silkworms are often used as a model for studying the mechanism of species domestication. Here, we performed transcriptome sequencing of the wild
Takeyori Saheki et al.
Molecular genetics and metabolism, 107(3), 322-329 (2012-08-28)
The C57BL/6:Slc23a13(-/-);Gpd2(-/-) double-knockout (a.k.a., citrin/mitochondrial glycerol 3-phosphate dehydrogenase double knockout or Ctrn/mGPD-KO) mouse displays phenotypic attributes of both neonatal intrahepatic cholestasis (NICCD) and adult-onset type II citrullinemia (CTLN2), making it a suitable model of human citrin deficiency. In the present
Cássia Borges Lima et al.
Life sciences, 93(9-11), 388-392 (2013-07-23)
Monosodium glutamate (MSG) is a neuroexcitatory amino acid used in human food to enhance flavor. MSG can affect the morphological and electrophysiological organization of the brain. This effect is more severe during brain development. Here, we investigated the electrophysiological and
Zumin Shi et al.
PloS one, 7(12), e51567-e51567 (2012-12-15)
Emerging evidence shows that diet is related to asthma. The aim of this analysis was to investigate the association between monosodium glutamate (MSG) intake, overall dietary patterns and asthma. Data from 1486 Chinese men and women who participated in the
Michael G Tordoff et al.
Physiology & behavior, 107(3), 338-345 (2012-08-08)
Monosodium glutamate (MSG) is pervasively consumed as a flavor enhancer so there are important implications to understanding its physiological actions, particularly its effects on body weight. Previous studies suggest that MSG increases, decreases, or has no effect on the body
I V Leshchenko et al.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 58(2), 59-65 (2012-08-10)
The influence of prolonged administration of monosodium glutamate (MSG) on pancreas in rats was studied. It was established that 30-days feeding by MSG in the doses 15 to 30 mg/kg (equivalent to 1 and 2 g/person) leads to necrotic, necrobiotic
M Mansour Ceesay et al.
British journal of haematology, 168(2), 219-229 (2014-09-03)
Invasive fungal disease (IFD) is difficult to diagnose. We investigated the incidence of IFD and risk factors using the revised European Organization for Research and Treatment of Cancer (EORTC) and the Mycoses Study Group (MSG) definitions. Patients (N = 203)
Kazuhiko Nakadate et al.
Ultrastructural pathology, 39(1), 30-37 (2014-09-06)
Obesity, which is one of the causes of the lifestyle-related disease, is a hepatopathic exacerbation factor that causes a chronic hepatic disorder. In this study, we examined the pathological changes in the liver in mice with obesity induced by monosodium
Md Shahidul Islam et al.
Methods in molecular biology (Clifton, N.J.), 933, 161-174 (2012-08-16)
Diabetes is one of the major global public health problems and is gradually getting worse particularly in developing nations where 95% of patients are suffering from type 2 diabetes (T2D). Animal models in diabetes research are very common where rodents
Nayara de Carvalho Leite et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 31(2-3), 242-256 (2013-03-08)
Obese rats obtained by neonatal monosodium glutamate (MSG) administration present insulin hypersecretion. The metabolic mechanism by which glucose catabolism is coupled to insulin secretion in the pancreatic β-cells from MSG-treated rats is understood. The purpose of this study was to
S D Gohel et al.
International journal of biological macromolecules, 56, 20-27 (2013-02-09)
An alkaline serine protease from a newly isolated salt-tolerant alkaliphilic actinomycetes, Brachystreptospora xinjiangensis OM-6 was purified with 35- and 26-fold purification and 47% and 22% yield employing two steps and one step methods, respectively. The enzyme was quite stable at
Reza Rezaei et al.
Amino acids, 44(3), 911-923 (2012-11-03)
Dietary intake of glutamate by postweaning pigs is markedly reduced due to low feed consumption. This study was conducted to determine the safety and efficacy of dietary supplementation with monosodium glutamate (MSG) in postweaning pigs. Piglets were weaned at 21
A D Stan et al.
Molecular psychiatry, 20(4), 433-439 (2014-06-11)
Hippocampal dysfunction in schizophrenia is widely acknowledged, yet the mechanism of such dysfunction remains debated. In this study we investigate the excitatory and inhibitory hippocampal neurotransmission using two complementary methodologies, proton magnetic resonance spectroscopy (MRS) and tissue biochemistry, sampling individuals
Natalia M Leguisamo et al.
Cardiovascular diabetology, 11, 100-100 (2012-08-18)
Metabolic syndrome is characterized by insulin resistance, which is closely related to GLUT4 content in insulin-sensitive tissues. Thus, we evaluated the GLUT4 expression, insulin resistance and inflammation, characteristics of the metabolic syndrome, in an experimental model. Spontaneously hypertensive neonate rats
Camille Schwartz et al.
The British journal of nutrition, 109(6), 1154-1161 (2012-08-10)
Early feeding experiences, e.g. related to milk feeding, can affect later food and taste preferences. However, consequences of breast-feeding on taste acceptance are under-investigated. The objective of the present study was to examine the impact of exclusive breast-feeding duration (DEB)
Pandian Nagakannan et al.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 31(3), 213-221 (2013-01-24)
Monosodium glutamate (MSG) is commonly used as a flavor enhancer in many countries. However, overconsumption of MSG has been reported to produce detrimental effects on several organs. It mainly affects the normal physiology and function of the brain and causes
Emma L Feeney et al.
Chemosensory perception, 7(3-4), 147-157 (2014-12-09)
The sense of taste is often referred to as a 'nutritional gatekeeper', thought to have evolved to indicate energy sources and prevent ingestion of potential toxins. Fungiform papillae are structures on the anterior tongue in which taste buds are situated.
M V Sauganth Paul et al.
Toxicology mechanisms and methods, 22(8), 625-630 (2012-07-26)
Chronic oral intake of high doses of monosodium glutamate (MSG) could be harmful to tissues and organs. Oxidative stress enhances membrane damage by lipid peroxidation and alterations of antioxidant enzymes, which affects the functional activity of organs. Antioxidant vitamins have
Fábio R F Seiva et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(10), 3556-3561 (2012-07-20)
We reported the effects of quercetin on metabolic and hormonal profile as well as serum antioxidant activities in a model of MSG (monosodium glutamate)-induced obesity. Rats were divided into 4 groups: MSG group, submitted to neonatal treatment with high doses
Abhishek Kumar et al.
Journal of oral & facial pain and headache, 29(1), 31-40 (2015-01-31)
To test the hypothesis that experimental pain in the masseter muscle or temporomandibular joint (TMJ) will decrease the anterior maximum voluntary bite force (MVBF) and jaw muscle activity in relation to the perceived effort. Sixteen volunteers participated in two experimental
O A Rotimi et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(11), 4062-4067 (2012-08-18)
In order to investigate the influence of some fibre-enriched diets on tissue lipids in an animal model of obesity induced by the administration of monosodium glutamate (MSG), obese rats were fed diets containing 30% of Acha, Cassava, Maize and Plantain
Amod Sharma et al.
PloS one, 9(12), e116233-e116233 (2015-01-01)
Chronic monosodium glutamate (MSG) intake causes kidney dysfunction and renal oxidative stress in the animal model. To gain insight into the renal changes induced by MSG, proteomic analysis of the kidneys was performed. Six week old male Wistar rats were
Tushar Gupta et al.
Journal of virology, 89(9), 5124-5133 (2015-02-27)
The E2F family of transcription factors, broadly divided into activator and repressor E2Fs, regulates cell cycle genes. Current models indicate that activator E2Fs are necessary for cell cycle progression and tumorigenesis and are also required to mediate transformation induced by
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