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Michael G Tordoff et al.
Physiology & behavior, 107(3), 338-345 (2012-08-08)
Monosodium glutamate (MSG) is pervasively consumed as a flavor enhancer so there are important implications to understanding its physiological actions, particularly its effects on body weight. Previous studies suggest that MSG increases, decreases, or has no effect on the body
I V Leshchenko et al.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 58(2), 59-65 (2012-08-10)
The influence of prolonged administration of monosodium glutamate (MSG) on pancreas in rats was studied. It was established that 30-days feeding by MSG in the doses 15 to 30 mg/kg (equivalent to 1 and 2 g/person) leads to necrotic, necrobiotic
M Mansour Ceesay et al.
British journal of haematology, 168(2), 219-229 (2014-09-03)
Invasive fungal disease (IFD) is difficult to diagnose. We investigated the incidence of IFD and risk factors using the revised European Organization for Research and Treatment of Cancer (EORTC) and the Mycoses Study Group (MSG) definitions. Patients (N = 203)
Kazuhiko Nakadate et al.
Ultrastructural pathology, 39(1), 30-37 (2014-09-06)
Obesity, which is one of the causes of the lifestyle-related disease, is a hepatopathic exacerbation factor that causes a chronic hepatic disorder. In this study, we examined the pathological changes in the liver in mice with obesity induced by monosodium
Zumin Shi et al.
PloS one, 7(12), e51567-e51567 (2012-12-15)
Emerging evidence shows that diet is related to asthma. The aim of this analysis was to investigate the association between monosodium glutamate (MSG) intake, overall dietary patterns and asthma. Data from 1486 Chinese men and women who participated in the
Md Shahidul Islam et al.
Methods in molecular biology (Clifton, N.J.), 933, 161-174 (2012-08-16)
Diabetes is one of the major global public health problems and is gradually getting worse particularly in developing nations where 95% of patients are suffering from type 2 diabetes (T2D). Animal models in diabetes research are very common where rodents
Takeyori Saheki et al.
Molecular genetics and metabolism, 107(3), 322-329 (2012-08-28)
The C57BL/6:Slc23a13(-/-);Gpd2(-/-) double-knockout (a.k.a., citrin/mitochondrial glycerol 3-phosphate dehydrogenase double knockout or Ctrn/mGPD-KO) mouse displays phenotypic attributes of both neonatal intrahepatic cholestasis (NICCD) and adult-onset type II citrullinemia (CTLN2), making it a suitable model of human citrin deficiency. In the present
Cássia Borges Lima et al.
Life sciences, 93(9-11), 388-392 (2013-07-23)
Monosodium glutamate (MSG) is a neuroexcitatory amino acid used in human food to enhance flavor. MSG can affect the morphological and electrophysiological organization of the brain. This effect is more severe during brain development. Here, we investigated the electrophysiological and
B Sagalajev et al.
Behavioural brain research, 282, 14-24 (2015-01-06)
Amygdala is involved in processing of primary emotions and particularly its central nucleus (CeA) also in pain control. Here we studied mechanisms mediating the descending control of mechanical hypersensitivity by the CeA in rats with a peripheral neuropathy in the
Nayara de Carvalho Leite et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 31(2-3), 242-256 (2013-03-08)
Obese rats obtained by neonatal monosodium glutamate (MSG) administration present insulin hypersecretion. The metabolic mechanism by which glucose catabolism is coupled to insulin secretion in the pancreatic β-cells from MSG-treated rats is understood. The purpose of this study was to
Longsheng Xu et al.
Journal of neurophysiology, 108(11), 3024-3033 (2012-09-21)
The tyrosine kinases of Src family play an important role in the central sensitization following peripheral inflammation. However, whether the Src family in the arcuate nucleus (ARC) of mediobasal hypothalamus is involved in central sensitization remains unknown. The aim of
Monosodium L-glutamate-induced asthma.
Allen, David H., John Delohery, and Gary Baker.
The Journal of Allergy and Clinical Immunology, 80.4, 530-537 (1987)
Karen Ackroff et al.
Physiology & behavior, 107(2), 207-217 (2012-07-11)
Monosodium glutamate (MSG), the prototypical umami substance, is used as a flavor enhancer in many foods, but when presented alone is often only weakly attractive. Yet with experience mice will develop strong preferences for MSG solution over water. The present
Tingcai Cheng et al.
PloS one, 10(3), e0122837-e0122837 (2015-03-26)
The wild silkworm Bombyx mandarina is widely believed to be an ancestor of the domesticated silkworm, Bombyx mori. Silkworms are often used as a model for studying the mechanism of species domestication. Here, we performed transcriptome sequencing of the wild
Katie M Di Sebastiano et al.
The British journal of nutrition, 110(12), 2165-2172 (2013-06-12)
Glutamate is linked to the glycolytic process, particularly when co-ingested with carbohydrate, but its effects on glucose metabolism are poorly characterised. The present study aimed to (1) specifically examine the effects of carbohydrate administration on circulating glutamate concentrations and (2)
Signorá Peres Konrad et al.
Clinics (Sao Paulo, Brazil), 67(10), 1209-1214 (2012-10-17)
The aim of this study was to evaluate cardiovascular autonomic function in a rodent obesity model induced by monosodium glutamate injections during the first seven days of life. The animals were assigned to control (control, n = 10) and monosodium
Nora Bourbia et al.
Neuroscience letters, 570, 26-31 (2014-04-22)
Amygdala has an important role in the processing of primary emotions, such as fear. Additionally, amygdala is involved in processing and modulation of pain. While the amygdala, particularly its central nucleus (CeA), has been shown to contribute to pain control
E von Hauff et al.
Biosensors & bioelectronics, 26(2), 596-601 (2010-08-07)
A biocompatible device for the voltage dependent uptake and release of the neural transmitter L-glutamate in neutral pH solutions is demonstrated. The device consists of a gold electrode coated with molecularly imprinted, overoxidised polypyrrole (oPPy). It is shown here that
Muheet Habib et al.
Journal of ethnopharmacology, 145(1), 18-24 (2012-11-03)
Artemisia scoparia (redstem wormwood) locally known as jhahoo or jaukay, is traditionally used in pain, inflammation and febrile conditions. So far, little or no scientific work has been reported to validate its folk uses in the alleviation of pain, fever
Caroline Bauchart-Thevret et al.
The Journal of nutrition, 143(5), 563-570 (2013-03-01)
Emerging evidence suggests that free glutamate may play a functional role in modulating gastroduodenal motor function. We hypothesized that supplementing monosodium glutamate (MSG) to partial enteral nutrition stimulates gastric emptying in preterm pigs. Ten-day-old preterm, parenterally fed pigs received partial
Jake G Hoekstra et al.
The American journal of pathology, 185(2), 536-549 (2014-12-09)
Mitochondrial dynamics has recently become an area of piqued interest in neurodegenerative disorders, including Parkinson disease (PD); however, the contribution of astrocytes to these disorders remains unclear. Here, we show that the level of dynamin-like protein 1 (Dlp1; official name
Derek M Kendig et al.
American journal of physiology. Gastrointestinal and liver physiology, 307(11), G1100-G1107 (2014-10-18)
Intraluminal nutrients in the gut affect the peristaltic reflex, although the mechanism is not well defined. Recent evidence supports the presence of taste receptors and their signaling components in enteroendocrine cells, although their function is unclear. This study aimed to
Jaewon Shim et al.
PloS one, 10(4), e0124030-e0124030 (2015-04-09)
Although the five basic taste qualities-sweet, sour, bitter, salty and umami-can be recognized by the respective gustatory system, interactions between these taste qualities are often experienced when food is consumed. Specifically, the umami taste has been investigated in terms of
The results of some studies involving animal models of obesity induced by monosodium glutamate are not conclusive.
X Wu et al.
European journal of clinical nutrition, 67(2), 228-228 (2013-01-17)
S D Gohel et al.
International journal of biological macromolecules, 56, 20-27 (2013-02-09)
An alkaline serine protease from a newly isolated salt-tolerant alkaliphilic actinomycetes, Brachystreptospora xinjiangensis OM-6 was purified with 35- and 26-fold purification and 47% and 22% yield employing two steps and one step methods, respectively. The enzyme was quite stable at
Glaura Sa Fernandes et al.
Reproductive biology and endocrinology : RB&E, 10, 105-105 (2012-12-12)
Given the established fact that obesity interferes with male reproductive functions, the present study aimed to evaluate sperm production in the testis and storage in the epididymis in a glutamate-induced model of obesity. Male rats were treated neonatally with monosodium
Mark L Dewis et al.
Journal of neurophysiology, 109(4), 1078-1090 (2012-12-12)
Effects of N-geranyl cyclopropyl-carboxamide (NGCC) and four structurally related compounds (N-cyclopropyl E2,Z6-nonadienamide, N-geranyl isobutanamide, N-geranyl 2-methylbutanamide, and allyl N-geranyl carbamate) were evaluated on the chorda tympani (CT) nerve response to NaCl and monosodium glutamate (MSG) in rats and wild-type (WT)
Jennifer Batson et al.
Biology open, 3(6), 453-462 (2014-05-06)
Metastatic prostate cancer cells display EphB receptor-mediated attraction when they contact stromal fibroblasts but EphA-driven repulsion when they contact one another. The impact of these 'social' interactions between cells during cancer cell invasion and the signalling mechanisms downstream of Eph
Eun-Seon Jeong et al.
Journal of microbiology and biotechnology, 22(10), 1406-1411 (2012-10-19)
5,5'-Dithiobis(2-nitrobenzoic acid) (DTNB) was selected as an electron transfer mediator and was covalently immobilized onto high porosity carbon cloth to employ as a working electrode in an electrochemical NAD(+)-regeneration process, which was coupled to an enzymatic reaction. The voltammetric behavior
Tushar Gupta et al.
Journal of virology, 89(9), 5124-5133 (2015-02-27)
The E2F family of transcription factors, broadly divided into activator and repressor E2Fs, regulates cell cycle genes. Current models indicate that activator E2Fs are necessary for cell cycle progression and tumorigenesis and are also required to mediate transformation induced by
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