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Merck
CN
  • No effects of monosodium glutamate consumption on the body weight or composition of adult rats and mice.

No effects of monosodium glutamate consumption on the body weight or composition of adult rats and mice.

Physiology & behavior (2012-08-08)
Michael G Tordoff, Tiffany R Aleman, Michelle C Murphy
摘要

Monosodium glutamate (MSG) is pervasively consumed as a flavor enhancer so there are important implications to understanding its physiological actions, particularly its effects on body weight. Previous studies suggest that MSG increases, decreases, or has no effect on the body weight of rodents. However, most of these studies involved administration of MSG to immature rodents and consequently may not be relevant for understanding human obesity. We report here five experiments in which we measured the body weights of a total of 32 groups of 10-12 adult rats or mice given various diets to eat and MSG to eat or drink. We found no evidence that MSG influenced body weight, energy intake, or body composition. To the extent that experiments in rodents illuminate mechanisms involved in human obesity and body weight control, our results suggest that MSG is unlikely to be a useful anti-obesity supplement but neither is it responsible for exacerbating obesity.

材料
Product Number
品牌
产品描述

Sigma-Aldrich
L-谷氨酸 单钠盐 水合物, ≥99% (HPLC), powder
Sigma-Aldrich
L-谷氨酸 单钠盐 水合物, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥99%
Supelco
L-谷氨酸 单钠盐 水合物, analytical standard
Sigma-Aldrich
L-谷氨酸 单钠盐 水合物, Vetec, reagent grade, ≥99%