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activates ALK3 and
ALK6. SB-505124 inhibits ALK5 and ALK4 with similar
IC50 values (47±5 nM and 129±11 nM, respectively), but
does not inhibit ALK2 up to concentrations of 10 µM.
SB-505124 demonstrated
mouse
ATP13A2. The antibody may be used in
immunochemical techniques including immunoblotting
(129 kDa). Detection of the ATP13A2 band by
immunoblotting is specifically inhibited by the ATP13A2
immunizing
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.1 mM EDTA,
0.1 mM PMSF, and 25% glycerol.
Molecular mass: ∼73 kDa
Purity: ≥70% (SDS-PAGE, see Figure 1)
Specific Activity: 95–129 nmole/min/mg (see Figure 2)
Precautions and Disclaimer
This
0.1 mM EDTA,
0.1 mM PMSF, and 25% glycerol.
Molecular mass: ∼73 kDa
Purity: ≥70% (SDS-PAGE, see Figure 1)
Specific Activity: 95–129 nmole/min/mg (see Figure 2)
Precautions and Disclaimer
This
Respiratory Research, 7, 53 (2006).
2. Fink, S.K. et al., Apoptosis, Pyroptosis, and
Necrosis: Mechanistic Description of Dead and
Dying Eukaryotic Cells. Infection and Immunity,
73(4), 1907-1916 (2005
Respiratory Research, 7, 53 (2006).
2. Fink, S.K. et al., Apoptosis, Pyroptosis, and
Necrosis: Mechanistic Description of Dead and
Dying Eukaryotic Cells. Infection and Immunity,
73(4), 1907-1916 (2005
Respiratory Research, 7, 53 (2006).
2. Fink, S.K. et al., Apoptosis, Pyroptosis, and
Necrosis: Mechanistic Description of Dead and
Dying Eukaryotic Cells. Infection and Immunity,
73(4), 1907-1916 (2005
Respiratory Research, 7, 53 (2006).
2. Fink, S.K. et al., Apoptosis, Pyroptosis, and
Necrosis: Mechanistic Description of Dead and
Dying Eukaryotic Cells. Infection and Immunity,
73(4), 1907-1916 (2005
Respiratory Research, 7, 53 (2006).
2. Fink, S.K. et al., Apoptosis, Pyroptosis, and
Necrosis: Mechanistic Description of Dead and
Dying Eukaryotic Cells. Infection and Immunity,
73(4), 1907-1916 (2005
Respiratory Research, 7, 53 (2006).
2. Fink, S.K. et al., Apoptosis, Pyroptosis, and
Necrosis: Mechanistic Description of Dead and
Dying Eukaryotic Cells. Infection and Immunity,
73(4), 1907-1916 (2005