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Zhen Zhou et al.
The Journal of general physiology, 120(5), 647-662 (2002-10-31)
The cystic fibrosis transmembrane conductance regulator (CFTR) is an ion channel that conducts Cl- current. We explored the CFTR pore by studying voltage-dependent blockade of the channel by two organic anions: glibenclamide and isethionate. To simplify the kinetic analysis, a
James Ziming Sun et al.
Journal of cosmetic science, 54(6), 559-568 (2004-01-20)
Sodium cocoyl isethionate (SCI) has been a predominant ingredient in syndet bar formulation for more than thirty years. Although cost effective and well recognized for good skin compatibility, SCI is not regularly found in liquid detergent systems due to its
Katharina Styp von Rekowski et al.
Archives of microbiology, 183(5), 325-330 (2005-05-11)
Klebsiella oxytoca TauN1 represents a group of isolates which utilise taurine (2-aminoethanesulfonate) quantitatively as a sole source of combined nitrogen for aerobic growth. During growth, a compound is excreted, which has now been identified as isethionate (2-hydroxyethanesulfonate). An ion-chromatographic separation
Arezue F B Boroujerdi et al.
Analytical and bioanalytical chemistry, 404(3), 777-784 (2012-07-10)
Nuclear magnetic resonance (NMR) spectroscopy has been used to obtain metabolic profiles of the polar diatom Fragilariopsis cylindrus, leading to the identification of a novel metabolite in this organism. Initial results from an ongoing metabolomics study have led to the
M Syringas et al.
Molecular pharmacology, 58(6), 1404-1411 (2000-11-28)
Catecholamine transporters constitute the biological targets for several important drugs, including antidepressants, cocaine, and related compounds. Some information exists about discrete domains of these transporters that are involved in substrate translocation and uptake blockade, but delineation of domains mediating the
Sonja Weinitschke et al.
Applied and environmental microbiology, 76(2), 618-621 (2009-11-26)
Ubiquitous isethionate (2-hydroxyethanesulfonate) is dissimilated by diverse bacteria. Growth of Cupriavidus necator H16 with isethionate was observed, as was inducible membrane-bound isethionate dehydrogenase (IseJ) and inducible transcription of the genes predicted to encode IseJ and a transporter (IseU). Biodiversity in
Judy A Libra et al.
Chemosphere, 56(2), 167-180 (2004-05-04)
A two stage anaerobic/aerobic bacterial process was used to decolorize and partially mineralize a reactive vinyl sulfone diazo dye C.I. Reactive Black 5 (RB5) in a synthetic wastewater. Since the anchor group of reactive dyes reacts during the dyeing process
Kiyoshi Egawa et al.
The Journal of physiology, 591(16), 3901-3917 (2013-06-05)
The electrophysiological properties and functional role of GABAergic signal transmission from neurons to the gap junction-coupled astrocytic network are still unclear. GABA-induced astrocytic Cl⁻ flux has been hypothesized to affect the driving force for GABAergic transmission by modulating [Cl⁻]o. Thus
Lei Zhang et al.
Biosensors & bioelectronics, 24(4), 690-695 (2008-08-19)
A composite film of polyaniline (PAN) nano-networks/p-aminobenzene sulfonic acid (ABSA) modified glassy carbon electrode (GCE) has been fabricated via an electrochemical oxidation procedure and applied to the electro-catalytic oxidation of uric acid (UA) and ascorbic acid (AA). The ABSA monolayer
Baowei Hu et al.
Molecules (Basel, Switzerland), 15(8), 5369-5377 (2010-08-18)
The novel carbon based acid has been synthesized via one-step hydrothermal carbonization of furaldehyde and hydroxyethylsulfonic acid. A highly efficient procedure for the synthesis of fructone has been developed using the novel carbon based acid. The results showed that the
L Gambling et al.
Biochimica et biophysica acta, 1372(2), 187-197 (1998-07-24)
In apical membrane vesicles (AMV) prepared from late gestation fetal guinea pig lung we show that conductive 22Na+ uptake is modulated by at least two pathways involving pertussis toxin (PTX)-sensitive G proteins. Intravesicular incorporation of 100 microM GTPgammaS into vesicles
Steven Bourke et al.
Respiratory research, 6, 40-40 (2005-04-29)
Lung fluid balance in the healthy lung is dependent upon finely regulated vectorial transport of ions across the alveolar epithelium. Classically, the cellular locus of the major ion transport processes has been widely accepted to be the alveolar type II
R A Tupker et al.
Contact dermatitis, 40(6), 316-322 (1999-06-29)
Discrepancies between the one-time patch test and the wash test regarding the ranking of irritancy of detergents have been found in the literature. The aim of the present study was to investigate the concordance of irritancy rank order of 4
E Kremer et al.
Journal of neurophysiology, 79(5), 2581-2592 (1998-05-20)
Dorsal root afferent depolarization and antidromic firing were studied in isolated spinal cords of neonatal rats. Spontaneous firing accompanied by occasional bursts could be recorded from most dorsal roots in the majority of the cords. The afferent bursts were enhanced
Kaustubh Sharma et al.
PloS one, 14(7), e0219784-e0219784 (2019-07-12)
Oxytocin is involved in the regulation of social behaviors including parental behaviors in a variety of species. Oxytocin triggers social behaviors by binding to oxytocin receptors (OXTRs) in various parts of the brain. OXTRs are present in the preoptic area
M Miquel et al.
Life sciences, 64(18), 1613-1621 (1999-05-18)
The effect of isethionic acid, a central metabolite of taurine, on ethanol-induced locomotor activity was investigated in rodents. Ten minutes following an (i.p.) simultaneous administration of ethanol (0.0, 1.5, 2.0, 2.5, 3.0, 3.5 g/kg) and isethionic acid (0.0, 22.5, 45.0
Zdenek Krejcík et al.
Microbiology (Reading, England), 156(Pt 5), 1547-1555 (2010-02-06)
Bacterial generation of isethionate (2-hydroxyethanesulfonate) from taurine (2-aminoethanesulfonate) by anaerobic gut bacteria was established in 1980. That phenomenon in pure culture was recognized as a pathway of assimilation of taurine-nitrogen. Based on the latter work, we predicted from genome-sequence data
Chang-Chin Kwan et al.
Chemical & pharmaceutical bulletin, 54(8), 1082-1087 (2006-08-02)
Suspension of concentrated kaolinite (20 g/30 ml-medium) in the presence of polyvinylpyrrolidone (PVP) and sodium lauroyl isethionate (SLI) was allowed to evaluate its degree of dispersion based on their rheological studies. Flow curves at low shear rate, measured by means
Claire Hellio et al.
Biofouling, 20(3), 139-145 (2004-11-17)
Isethionic acid (2-hydroxyethane sulfonic acid) and floridoside (2-O-alpha-D-galactopyranosylglycerol) were extracted from the red alga, Grateloupia turuturu, and tested for anti-settlement activity against cyprid larvae of the tropical barnacle, Balanus amphitrite and for their toxicity to nauplius larvae. Isethionic acid was
Christelle Simon-Colin et al.
Plant physiology and biochemistry : PPB, 42(1), 21-26 (2004-04-06)
The red alga Grateloupia doryphora Montagne (Howe) (Cryptonemiales, Halymeniaceae) was used as a model to investigate the effects of changes in seawater salinity on the intracellular low-molecular-weight organic compounds. Carbon-partitioning into major organic solutes was followed by 13C nuclear magnetic
Wesley N Sivak et al.
Acta biomaterialia, 6(1), 144-153 (2009-06-16)
This study seeks to determine the effect of ionic ligands on the drug delivery characteristics of biodegradable polyurethane materials synthesized from lysine diisocyanate (LDI) and glycerol. Two naturally occurring, structurally related ionic species, choline chloride (CC) and isethionic acid (ISE)
Ping Zhong et al.
PloS one, 6(2), e16970-e16970 (2011-03-09)
Serotonin exerts a powerful influence on neuronal excitability. In this study, we investigated the effects of serotonin on different neuronal populations in prefrontal cortex (PFC), a major area controlling emotion and cognition. Using whole-cell recordings in PFC slices, we found
Lei Gong et al.
Toxicological sciences : an official journal of the Society of Toxicology, 122(2), 587-597 (2011-05-13)
Organic anion-transporting polypeptides (Oatp) 1a1 and 1a4 were deleted by homologous recombination, and mice were characterized for Oatp expression in liver and kidney, transport in isolated hepatocytes, in vivo disposition of substrates, and urinary metabolomic profiles. Oatp1a1 and Oatp1a4 proteins
Saswata Ghosh et al.
Journal of cosmetic science, 58(3), 229-244 (2007-06-29)
Sodium cocoyl isethionate (SCI) is an important surfactant ingredient in mild, syndet (synthetic detergent) cleansing bars. In vitro and in vivo studies have demonstrated that SCI is mild and less damaging to the skin barrier than soaps and surfactants such
Christopher D Dawson et al.
Cell chemical biology, 28(9), 1333-1346 (2021-03-28)
Desulfonation of isethionate by the bacterial glycyl radical enzyme (GRE) isethionate sulfite-lyase (IslA) generates sulfite, a substrate for respiration that in turn produces the disease-associated metabolite hydrogen sulfide. Here, we present a 2.7 Å resolution X-ray structure of wild-type IslA from
Wei Tang et al.
Drug metabolism and disposition: the biological fate of chemicals, 30(7), 778-787 (2002-06-18)
(R)-N-[4-[2-[[2-Hydroxy-2-(pyridin-3-yl)ethyl]amino]ethyl]phenyl]- 4-[4-(4-trifluoro-methylphenyl)thiazol-2-yl]benzenesulfonamide (1) is a potent and selective agonist of the human beta3-adrenergic receptor. We report herein the data from studies of the metabolism and excretion of 1 in rats. Five metabolites were identified in the bile of male Sprague-Dawley
C Nabel et al.
Pflugers Archiv : European journal of physiology, 438(5), 694-699 (1999-11-11)
The aim of this study was to assess the relevance of chloride channels to the inhibitory effect of angiotensin II (ANGII) on renin secretion. We thus examined the effects of the chloride channels blockers IAA-94 and niflumic acid, the Na-K-Cl
S Kearns et al.
Advances in experimental medicine and biology, 483, 563-570 (2002-01-15)
Taurine has been shown to be an effective scavenger of hypochlorous acid (HOCl). The role of HOCl is well established in tissue damage associated with reperfusion injury mediated by neutrophils. The role of HOCl in CNS injury and inflammatory reactions
M Haque et al.
Journal of neuroendocrinology, 27(11), 835-849 (2015-09-26)
An accumulating body of evidence suggests that the activity of the mineralocorticoid, aldosterone, in the brain via the mineralocorticoid receptor (MR) plays an important role in the regulation of blood pressure. MR was recently found in vasopressin and oxytocin synthesising
Chantal Brüggemann et al.
Microbiology (Reading, England), 150(Pt 4), 805-816 (2004-04-10)
Growth of the alpha-proteobacterium Paracoccus denitrificans NKNIS with taurine or isethionate as sole source of carbon involves sulfoacetaldehyde acetyltransferase (Xsc), which is presumably encoded by an xsc gene in subgroup 3, none of whose gene products has been characterized. The
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