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Wei Sun et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 1907-1913 (2013-03-19)
In this paper a platinum (Pt) nanoparticle decorated graphene (GR) nanosheet was synthesized and used for the investigation on direct electrochemistry of myoglobin (Mb). By integrating GR-Pt nanocomposite with Mb on the surface of carbon ionic liquid electrode (CILE), a
Platinum-free catalysts as counter electrodes in dye-sensitized solar cells.
Mingxing Wu et al.
ChemSusChem, 5(8), 1343-1357 (2012-08-14)
Xiao-yong Shen et al.
PloS one, 8(8), e69553-e69553 (2013-08-14)
X-ray repair cross-complementing protein 3 (XRCC3) is an essential gene involved in the double-strand break repair pathway. Published evidence has shown controversial results about the relationship between XRCC3 Thr241Met polymorphism and clinical outcomes of non-small cell lung cancer (NSCLC) patients
Josep Ramon Germà-Lluch et al.
Archivos espanoles de urologia, 66(5), 524-535 (2013-06-26)
Cisplatin has been the cornerstone of germ cell testicular tumors therapy since its introduction more tan 30 years ago, and a basic part of the schemes given to multiple ovarian, lung, head and neck, and bladder tumors among others. Some
K M Moxley et al.
Gynecologic oncology, 130(2), 377-382 (2013-05-02)
This study aims to assess the role of polymorphisms in DNA repair genes, excision repair cross-complementation group 1 (ERCC1) and methyl-methanesulfonate sensitivity 19 (MMS19), in tumor response to platinum-based chemotherapy and survival in advanced epithelial ovarian cancer (EOC). Single nucleotide
Bernd Reitemeier et al.
The Journal of prosthetic dentistry, 109(3), 149-155 (2013-03-26)
Metal ceramic restorations are widely used in prosthodontics, but long-term data on their clinical performance in private practice settings based on prospective trials are sparse. This clinical trial was designed to provide realistic long-term survival rates for different outcomes related
Xiaoyong Wang et al.
Chemical Society reviews, 42(1), 202-224 (2012-10-09)
Platinum-based anticancer drugs occupy a crucial role in the treatment of various malignant tumours. However, the efficacy and applicability of platinum drugs are heavily restricted by severe systemic toxicities and drug resistance. Different drug targeting and delivery (DTD) strategies have
A G Quiroga
Journal of inorganic biochemistry, 114, 106-112 (2012-07-24)
This focused review is devoted to our advances in developing trans platinum complexes as antitumoral complexes, in particular those bearing aliphatic amines. It includes some fundamental aspects of the understanding of non conventional metallodrug mechanism. The perspective is arranged by
Jianbo Wu et al.
Accounts of chemical research, 46(8), 1848-1857 (2013-07-03)
An efficient oxygen reduction reaction (ORR) offers the potential for clean energy generation in low-temperature, proton-exchange membrane fuel cells running on hydrogen fuel and air. In the past several years, researchers have developed high-performance electrocatalysts for the ORR to address
Yuan Xiong et al.
Organic letters, 15(8), 1962-1965 (2013-04-12)
Metal-mediated rearrangements of 3-alkynyl flavone ethers are reported. The overall process involves 5-endo enyne cyclization to a platinum-containing spiro-oxocarbenium intermediate which may be trapped with methanol to produce spirodihydrofurans or further rearranged to afford either allenyl chromanediones or benzofuranones.
Somayeh Tajik et al.
Journal of AOAC International, 96(1), 204-211 (2013-03-22)
This paper describes the construction and performance characteristics of novel polyvinyl chloride membrane (PME) and coated platinum (CPtE) aluminium (Al) ion selective electrodes based on E-N'-(2-hydroxy-3-methoxybenzylidene) benzohydrazide. The electrodes exhibited linear responses with near Nernstian slopes of 19.9 +/- 0.3
Loris De Cecco et al.
PloS one, 8(3), e58849-e58849 (2013-03-14)
We recently reported that peritumoral CpG-ODN treatment, activating TLR-9 expressing cells in tumor microenvironment, induces modulation of genes involved in DNA repair and sensitizes cancer cells to DNA-damaging cisplatin treatment. Here, we investigated whether this treatment induces modulation of miRNAs
Shai Rozen et al.
Plastic and reconstructive surgery, 131(6), 1253-1265 (2013-05-30)
Left untreated, paralytic lagophthalmos may result in corneal dryness, ulcerations, and subsequent blindness. The most common nondynamic surgical solution is upper eyelid weight placement in a superficial, pretarsal pocket, carrying the risk of visibility, extrusion, and entropion. The authors present
C Mohn et al.
Die Pharmazie, 68(7), 622-627 (2013-08-09)
Albeit platinum complexes are widely used in cancer chemotherapy, their cellular processing has not been completely elucidated so far. In this study the effects of modulating multidrug resistance-associated protein (MRP)-mediated efflux and glutathione (GSH) depletion on the cytotoxicity of oxaliplatin
Dusan Strmcnik et al.
Nature chemistry, 5(4), 300-306 (2013-03-21)
The development of hydrogen-based energy sources as viable alternatives to fossil-fuel technologies has revolutionized clean energy production using fuel cells. However, to date, the slow rate of the hydrogen oxidation reaction (HOR) in alkaline environments has hindered advances in alkaline
Gaixia Zhang et al.
Scientific reports, 3, 1526-1526 (2013-03-26)
Controlling the morphology of Pt nanostructures can provide opportunities to greatly increase their activity and stability. Porous dendritic Pt nanotubes were successfully synthesized by a facile, cost-effective aqueous solution method at room temperature in large scale. These unique structures are
Nguyen Viet Long et al.
Journal of nanoscience and nanotechnology, 13(7), 4799-4824 (2013-08-02)
In this review, we present the synthesis and characterization of Pt, Pd, Pt based bimetallic and multi-metallic nanoparticles with mixture, alloy and core-shell structure for nano-catalysis, energy conversion, and fuel cells. Here, Pt and Pd nanoparticles with modified nanostructures can
Johnson J Liu et al.
Current cancer drug targets, 12(8), 962-986 (2012-07-17)
Membrane transporters govern the movement of drugs and their metabolites across biological membranes, thereby determining their pharmacokinetics, efficacy and adverse drug reactions. Platinum-based anticancer drugs are a mainstay of chemotherapy for many human malignancies. However, their clinical utility is limited
Dalian Ding et al.
Anatomical record (Hoboken, N.J. : 2007), 295(11), 1851-1867 (2012-10-10)
Cisplatin, carboplatin, nedaplatin, and oxaliplatin are widely used in contemporary oncology; however, their ototoxic and neurotoxic side effects are quite different as discussed in this review. Cisplatin is considered the most ototoxic, but despite its reputation, the magnitude of hair
Jae Young Park et al.
Journal of nanoscience and nanotechnology, 13(3), 2213-2217 (2013-06-13)
Conductive carbon black supported Pt-Pd nanocomposites were prepared to study a difference of simultaneously and sequentially reduced Pt-Pd nanocomposites using polyol method. The concentration of Pt-Pd alloyed metals on carbon blacks (CB) was adjusted to 20 wt%. The catalysts could
Jae-Young Lee et al.
Journal of nanoscience and nanotechnology, 13(5), 3634-3637 (2013-07-19)
A simple method for the synthesis of Pt-Pd nanocatalysts was developed for a proton-exchange membrane fuel cell (PEMFC), which was loaded on a nafion coated carbon black via the sequential reduction of palladium(II) bis(acetylacetonato) and platinum(II) bis(acetylacetonato) in a drying
Yanqin Cao et al.
Journal of nanoscience and nanotechnology, 14(2), 1194-1208 (2014-04-23)
Porous platinum, that has outstanding catalytic and electrical properties and superior resistant characteristics to corrosion, has been widely applied in chemical, petrochemical, pharmaceutical, electronic, and automotive industries. As the catalytic activity and selectivity depend on the size, shape and structure
Y Yamagishi et al.
Die Pharmazie, 68(3), 178-182 (2013-04-06)
Nano-sized materials are widely used in consumer products, medical devices and engineered pharmaceuticals. Advances in nanotechnology have resulted in materials smaller than the nanoscale, but the biologic safety of the sub-nanosized materials has not been fully assessed. In this study
Živadin D Bugarčić et al.
Dalton transactions (Cambridge, England : 2003), 41(40), 12329-12345 (2012-08-15)
A brief overview of mechanistic studies on the reactions of different Pt(II) complexes with nitrogen- and sulfur-donor biomolecules is presented. The first part describes the results obtained for substitution reactions of mono-functional Pt(II) complexes with different biomolecules, under various experimental
N H H Abu Bakar et al.
Journal of nanoscience and nanotechnology, 13(7), 5034-5043 (2013-08-02)
A detailed study on the surface properties of oleic acid-stabilized PtNi nanoparticles supported on silica is reported. The oleic acid-stabilized PtNi nanoparticles were synthesized using NaBH4 as the reducing agent at various temperatures and oleic acid concentrations, prior to incorporation
Yanlong Yang et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(4), 2905-2921 (2013-12-18)
The relationship between the ERCC1/2 single nucleotide polymorphisms (SNPs) and the clinical outcomes of the platinum-based chemotherapy in the non-small cell lung cancer (NSCLC) is still inconsistent and inconclusive despite extensive investigations have been conducted to address this question. In
Muhammad Rashid et al.
Journal of nanoscience and nanotechnology, 13(5), 3627-3633 (2013-07-19)
Platinum nanoparticles (Pt NPs) were chemically deposited on a Nafion polymer electrolyte membrane by the impregnation-reduction (I-R) procedure to prepare an active electrode for solid electrochemical sensors. Various analysis methods such as SEM, EDX, XRD and cyclic voltammogram (CV) measurements
Michele Iafisco et al.
Journal of inorganic biochemistry, 117, 237-247 (2012-07-25)
The present review focuses on the "drug targeting and delivery" approach of the selective transportation of cisplatin to bone tumors and bone metastases. This aim is realized by binding cisplatin to (bis)phosphonate ligands or their derivatives. Geminal bisphosphonates are in
Tao Xiong et al.
Journal of biomedical nanotechnology, 9(2), 274-280 (2013-05-01)
Noninvasive molecular fluorescence imaging in vivo which combines Optical imaging with genetic marker technology can real time monitor the development of tumor, through the use of human adenoid cystic carcinoma cell (ACC-M) and lung carcinoma cells SPC-A1 were thansfected by
Pei-Miao Li et al.
Ying yong sheng tai xue bao = The journal of applied ecology, 23(12), 3514-3525 (2013-03-14)
Anthropogenic platinum group elements (PGEs) are widely applied in vehicle exhaust catalytic converters (VECs), industrial catalysts, and pharmaceutics, making the PGEs, especially Pt, Pd, and Rh, become the newly environmental pollutants in some fields. Given the positive correlations between the
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