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A Haese et al.
Journal of molecular biology, 243(1), 116-122 (1994-10-14)
Enniatin synthetase catalyzes the biosynthesis of N-methylated cyclohexadepsipeptides. The 347 kDa enzyme is encoded by the esyn1 gene of Fusarium scirpi and contains two domains (EA and EB) homologous to each other and to regions of other microbial peptide synthetases.
Hye-Ran Yoon
Archives of pharmacal research, 30(3), 387-395 (2007-04-12)
A rapid dried-filter paper plasma-spot analytical method was developed to quantify organic acids, amino acids, and glycines simultaneously in a two-step derivatization procedure with good sensitivity and specificity. The new method involves a two-step trimethylsilyl (TMS) - trifluoroacyl (TFA) derivatization
M Friedrich et al.
Zeitschrift fur Urologie und Nephrologie, 82(2), 105-112 (1989-02-01)
Rats were fed protein-restricted after unilateral nephrectomy (6.7% casein). Comparatively other animals were fed with experimental diets, at which 20% of the casein have been replaced by Ketosteril or a mixture of hydroxy acid. The constituents of this mixture are
L P Evanylo et al.
Canadian journal of microbiology, 30(8), 1046-1051 (1984-08-01)
Studies on the isolation and characterization of Proteus mirabilis siderophores provided no evidence that these bacteria synthesize catechol- or hydroxamate-type siderophores. However, gas chromatograph analysis in conjunction with mass spectroscopy revealed the presence of alpha-hydroxyisovaleric acid, a previously unknown metabolite.
Journal of the American Chemical Society, 112, 7659-7659 (1990)
L Hagenfeldt et al.
Clinica chimica acta; international journal of clinical chemistry, 169(1), 77-83 (1987-10-30)
N-Lactylvaline, N-lactylleucine, N-lactylisoleucine and the N-2-hydroxyisovaleryl conjugates of glycine, valine, leucine and isoleucine have been identified in urine from a patient with the intermediate type of maple syrup urine disease.
Alexandre Umpierrez Amaral et al.
Brain research, 1324, 75-84 (2010-02-16)
Patients affected by maple syrup urine disease (MSUD) present severe neurological symptoms and brain abnormalities, whose pathophysiology is poorly known. In the present study we investigated the in vitro effects of leucine (Leu), alpha-ketoisocaproic acid (KIC) and alpha-hydroxyisovaleric acid (HIV)
K P Boebel et al.
The Journal of nutrition, 112(10), 1929-1939 (1982-10-01)
Several experiments were conducted to quantitatively evaluate the growth-promoting capacity of the isomers of the branched-chain amino acids (BCAA) and their alpha-hydroxy and alpha-keto analogs for the chick and rat. Basal chemically defined diets were formulated to be singly deficient
K R Kim et al.
Journal of chromatography. A, 874(1), 91-100 (2000-04-18)
An efficient method is described for the simultaneous enantiomeric separation of 18 different racemic 2-hydroxy acids for the determination of their absolute configurations. It involves the conversion of each enantiomer into a diastereomeric O-trifluoroacetylated (S)-(+)-3-methyl-2-butyl ester for the direct separation
Immunosuppressive effects of organic acids accumulating in patients with maple syrup urine disease.
M Wajner et al.
Journal of inherited metabolic disease, 18(2), 165-168 (1995-01-01)
Characteristic urine organic acid profile in peroxisomal biogenesis disorders.
S H Korman et al.
Journal of inherited metabolic disease, 23(4), 425-428 (2000-07-15)
O Arad et al.
Biopolymers, 29(12-13), 1633-1649 (1990-10-01)
Depsipeptide analogues of peptide sequences can help in elucidating the role of specific hydrogen bonds in determining the conformation in peptides. The repeating pentapeptide and hexapeptide sequences of elastin have been suggested to contain a type II beta-turn with a
Yuquan Xu et al.
Fungal genetics and biology : FG & B, 46(5), 353-364 (2009-03-17)
Beauveria bassiana is a facultative entomopathogen with an extremely broad host range that is used as a commercial biopesticide for the control of insects of agricultural, veterinary and medical significance. B. bassiana produces bassianolide, a cyclooligomer depsipeptide secondary metabolite. We
V Walker et al.
Biology of the neonate, 61(3), 162-172 (1992-01-01)
Using capillary gas chromatography-mass spectrometry, the effects of birth asphyxia on the urinary organic acid profile of term babies was investigated. Random urine samples were collected on days 1 and 8 from 19 babies with fetal distress, 19 with moderate
Disturbances of valine metabolism in patients with peroxisomal biogenesis disorders.
Francois J M Eyskens et al.
Advances in experimental medicine and biology, 544, 73-74 (2004-01-10)
Schmidt, U. et al.
Synthesis, 294-294 (1991)
Biotinidase deficiency: metabolites in CSF.
A Fois et al.
Journal of inherited metabolic disease, 9(3), 284-285 (1986-01-01)
C Jakobs et al.
Clinica chimica acta; international journal of clinical chemistry, 140(2), 157-166 (1984-07-16)
A method is described in which ammonia chemical ionization gas chromatography-mass spectrometry was utilized in the selected ion monitoring mode to provide an accurate, selective approach to the quantification in amniotic fluid of a number of hydroxylated organic acids derived
Gregory Kaler et al.
The Journal of biological chemistry, 282(33), 23841-23853 (2007-06-08)
Organic anion transporters (OATs, SLC22) interact with a remarkably diverse array of endogenous and exogenous organic anions. However, little is known about the structural features that determine their substrate selectivity. We examined the substrate binding preferences and transport function of
T Kuhara et al.
Clinica chimica acta; international journal of clinical chemistry, 133(2), 133-140 (1983-09-30)
Using gas chromatography-mass spectrometry (GC/MS), urinary organic acid profile studies were carried out on a patient with dihydrolipoyl dehydrogenase (E3) deficiency. Elevated levels of 2-hydroxyglutaric acid, 2-hydroxyisocaproic acid and 2-oxoisocaproic acid were observed in addition to lactic acid, 2-oxoglutaric acid
Divya Misra et al.
Physiological chemistry and physics and medical NMR, 40, 67-88 (2008-01-01)
High-Resolution Magic Angle Spinning (HR-MAS) NMR has been employed to characterize various metabolites of human pancreas, liver and brain tissues from trauma cases. The potential usefulness of NMR in identifying the metabolites in human tissues has been explored using a
Identification of 3-hydroxyisovalerylcarnitine in the urine of a patient with multiple carboxylase deficiency.
T Nakanishi et al.
Annals of clinical biochemistry, 30 ( Pt 3), 318-320 (1993-05-01)
Pettit, G.R. et al.
Journal of the American Chemical Society, 113, 6692-6692 (1991)
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