[The growth of rats in renal compensatory adaptation in feeding with a supplemented diet of hydroxy-analogs of essential amino acids].

Rats were fed protein-restricted after unilateral nephrectomy (6.7% casein). Comparatively other animals were fed with experimental diets, at which 20% of the casein have been replaced by Ketosteril or a mixture of hydroxy acid. The constituents of this mixture are in accordance with the molar relation of all Ketosteril components. However, sodium solts of hydroxy acids of leucine, isoleucine and valin replace the corresponding keto acids of Ketosteril. The other components of the mixture consist of free amino acids. The efficiency of protein utilisation was judged by the relation of increased body weight and nitrogen intake. The efficiency of protein utilisation of both supplemented diets is 2.5 times higher compared with the casein diet.