647535

应用筛选条件

关键词:'647535'

显示 1-30 共 136 条结果关于 "647535" 范围论文

Initial reaction of dimethylaluminum isopropoxide with hydrogen-terminated Si (001) surface using density functional theory.

Dae-Hee Kim et al.

Journal of nanoscience and nanotechnology, 13(5), 3564-3567 (2013-07-19)

The initial reaction of dimethylaluminum isopropoxide (Al(CH3)2OC3H7, DMAI) with a fully hydrogen-terminated Si (001) surface for aluminum oxide thin-film growth was investigated using density functional theory. Al-C and Al-O bonds of the adsorbed DMAI were easily broken to produce unimethylaluminum

Quantification of chemical elements in blood of patients affected by multiple sclerosis.

Giovanni Forte et al.

Annali dell'Istituto superiore di sanita, 41(2), 213-216 (2005-10-26)

Although some studies suggested a link between exposure to trace elements and development of multiple sclerosis (MS), clear information on their role in the aetiology of MS is still lacking. In this study the concentrations of Al, Ba, Be, Bi

(28)silicon radiation impairs neuronal output in CA1 neurons of mouse ventral hippocampus without altering dendritic excitability.

Emil Rudobeck et al.

Radiation research, 181(4), 407-415 (2014-03-15)

An unavoidable complication of space travel is exposure to radiation consisting of high-energy charged particles (HZE), such as Fe and Si nuclei. HZE radiation can affect neuronal functions at the level of the synapse or neuronal soma without inducing significant

Radiation-induced alterations in synaptic neurotransmission of dentate granule cells depend on the dose and species of charged particles.

V N Marty et al.

Radiation research, 182(6), 653-665 (2014-11-18)

The evaluation of potential health risks associated with neuronal exposure to space radiation is critical for future long duration space travel. The purpose of this study was to evaluate and compare the effects of low-dose proton and high-energy charged particle

Simple fabrication of antireflective silicon subwavelength structure with self-cleaning properties.

Bo-Soon Kim et al.

Journal of nanoscience and nanotechnology, 13(5), 3622-3626 (2013-07-19)

A subwavelength structure (SWS) was formed via a simple chemical wet etching using a gold (Au) catalyst. Single nano-sized Au particles were fabricated by metallic self-aggregation. The deposition and thermal annealing of the thin metallic film were carried out. Thermal

Plasma beta-phenylethylamine in Parkinson's disease.

Y Miura

The Kurume medical journal, 47(4), 267-272 (2001-02-24)

Plasma beta-phenylethylamine (PEA) levels were determined in 27 patients with Parkinson's disease (PD) in order to evaluate its relation with the severity or clinical course of PD. The plasma PEA concentrations in PD patients were significantly lower (mean +/- SD

Inflammatory multiple-sclerosis plaques generate characteristic metabolic profiles in cerebrospinal fluid.

Norbert W Lutz et al.

PloS one, 2(7), e595-e595 (2007-07-06)

Multiple sclerosis (MS), an inflammatory disease of the central nervous system, manifests itself in numerous forms and stages. A number of brain metabolic alterations have been reported for MS patients vs. control subjects. However, metabolite profiles of cerebrospinal fluid (CSF)

Investigation of emulsified, acid and acid-alkali catalyzed mesoporous bioactive glass microspheres for bone regeneration and drug delivery.

Guohou Miao et al.

Materials science & engineering. C, Materials for biological applications, 33(7), 4236-4243 (2013-08-06)

Acid-catalyzed mesoporous bioactive glass microspheres (MBGMs-A) and acid-alkali co-catalyzed mesoporous bioactive glass microspheres (MBGMs-B) were successfully synthesized via combination of sol-gel and water-in-oil (W/O) micro-emulsion methods. The structural, morphological and textural properties of mesoporous bioactive glass microspheres (MBGMs) were characterized

Silicon impurity release and surface transformation of TiO2 anatase and rutile nanoparticles in water environments.

Xuyang Liu et al.

Environmental pollution (Barking, Essex : 1987), 184, 570-578 (2013-11-05)

Surface transformation can affect the stability, reactivity, and toxicity of titanium dioxide (TiO2) nanoparticles (NPs) in water environments. Herein, we investigated the release kinetics of Si impurity frequently introduced during NP synthesis and the resulting effect on TiO2 NP transformation

Surface chemistry of porous silicon and implications for drug encapsulation and delivery applications.

Karyn L Jarvis et al.

Advances in colloid and interface science, 175, 25-38 (2012-04-24)

Porous silicon (pSi) has a number of unique properties that appoint it as a potential drug delivery vehicle; high loading capacity, controllable surface chemistry and structure, and controlled release properties. The native Si(y)SiH(x) terminated pSi surface is highly reactive and

Markers of dopamine metabolism in Parkinson's disease. The Parkinson Study Group.

P A LeWitt et al.

Neurology, 42(11), 2111-2117 (1992-11-01)

We used two analytic methods (a multichannel coulometric electrode array with high-performance liquid chromatography, and gas chromatography-mass spectrophotometry) to measure CSF dopamine (DA) and its metabolites in mildly affected, unmedicated subjects with Parkinson's disease (PD). The mean (+/- SD) concentration

Ultrathin silicon membranes for wearable dialysis.

Dean G Johnson et al.

Advances in chronic kidney disease, 20(6), 508-515 (2013-11-12)

The development of wearable or implantable technologies that replace center-based hemodialysis (HD) hold promise to improve outcomes and quality of life for patients with ESRD. A prerequisite for these technologies is the development of highly efficient membranes that can achieve

Pentosidine and N(epsilon)-(carboxymethyl)-lysine in Alzheimer's disease and vascular dementia.

K J Bär et al.

Neurobiology of aging, 24(2), 333-338 (2002-12-25)

Increasing evidence suggests an interaction of oxidative stress and the formation of advanced glycation end products (AGE) in the onset and progression of Alzheimer's disease. We studied levels of pentosidine and N(epsilon)-(carboxymethyl)-lysine (CML) in serum and cerebrospinal fluid (CSF) of

Cell death of dopamine neurons in aging and Parkinson's disease.

M Naoi et al.

Mechanisms of ageing and development, 111(2-3), 175-188 (2000-02-03)

Dopamine neurons in the substantia nigra of human brain are selectively vulnerable and the number decline by aging at 5-10% per decade. Enzymatic and non-enzymatic oxidation of dopamine generates reactive oxygen species, which induces apoptotic cell death in dopamine neurons.

Silicon chemistry as a novel source of chemical diversity in drug design.

William Bains et al.

Current opinion in drug discovery & development, 6(4), 526-543 (2003-09-04)

The use of organosilicon chemistry in drug design is reviewed. The field of bioorganosilicon chemistry, which sprung up in the 1970s to exploit the opportunities of silicon for drug design, is currently being developed into a practical and commercial enterprise.

Disruption of thiol homeostasis and nitrosative stress in the cerebrospinal fluid of patients with active multiple sclerosis: evidence for a protective role of acetylcarnitine.

V Calabrese et al.

Neurochemical research, 28(9), 1321-1328 (2003-08-27)

Recent studies suggest that NO and its reactive derivative peroxynitrite are implicated in the pathogenesis of multiple sclerosis (MS). Patients dying with MS demonstrate increased astrocytic inducible nitric oxide synthase activity, as well as increased levels of iNOS mRNA. Peroxynitrite

Alleviation of cadmium toxicity by silicon is related to elevated photosynthesis, antioxidant enzymes; suppressed cadmium uptake and oxidative stress in cotton.

Muhammad Ahsan Farooq et al.

Ecotoxicology and environmental safety, 96, 242-249 (2013-08-06)

Biotic systems face immense environmental hazards such as accumulation of heavy metals, particularly in agricultural ecosystems that might cause deterioration of yield and quality of crops. In this study, we evaluated the role of silicon (Si) in alleviating the heavy

Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients.

Anna Walter et al.

Neurobiology of aging, 25(10), 1299-1303 (2004-10-07)

Experimental and clinical studies give evidence for breakdown of membrane phospholipids during neurodegeneration. In the present study, we measured the levels of glycerophosphocholine (GPCh), phosphocholine (PCh), and choline, that is, water-soluble metabolites of phosphatidylcholine (PtdCho), in human cerebrospinal fluid (CSF).

Chemical processing of materials on silicon: more functionality, smaller features, and larger wafers.

Nathan Marchack et al.

Annual review of chemical and biomolecular engineering, 3, 235-262 (2012-06-14)

The invention of the transistor followed by more than 60 years of aggressive device scaling and process integration has enabled the global information web and subsequently transformed how people communicate and interact. The principles and practices built upon chemical processing

Remarkable increase in the concentration of 8-hydroxyguanosine in cerebrospinal fluid from patients with Alzheimer's disease.

Takashi Abe et al.

Journal of neuroscience research, 70(3), 447-450 (2002-10-23)

To investigate the possible role of oxidative RNA damage in the pathogenesis of Alzheimer's disease (AD), the concentrations of the oxidative stress marker 8-hydroxyguanosine (8-OHG) were measured in the cerebrospinal fluid (CSF) and the serum of patients with AD and

A 5-day method for determination of soluble silicon concentrations in nonliquid fertilizer materials using a sodium carbonate-ammonium nitrate extractant followed by visible spectroscopy with heteropoly blue analysis: single-laboratory validation.

Dennis Sebastian et al.

Journal of AOAC International, 96(2), 251-259 (2013-06-19)

A 5-day method for determining the soluble silicon (Si) concentrations in nonliquid fertilizer products was developed using a sodium carbonate (Na2CO3)-ammonium nitrate (NH4NO3) extractant followed by visible spectroscopy with heteropoly blue analysis at 660 nm. The 5-Day Na2CO3-NH4NO3 Soluble Si

Three methods for 18F labeling of the HER2-binding affibody molecule Z(HER2:2891) including preclinical assessment.

Matthias Glaser et al.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(11), 1981-1988 (2013-10-12)

Human epidermal growth factor receptor (HER2)-targeted Affibody molecules radiolabeled with (18)F allow the noninvasive assessment of HER2 status in vivo through PET imaging. Such agents have the potential to improve patient management by selecting individuals for HER2-targeted therapies and allowing

The anomaly of silicon in plant biology.

E Epstein

Proceedings of the National Academy of Sciences of the United States of America, 91(1), 11-17 (1994-01-04)

Silicon is the second most abundant element in soils, the mineral substrate for most of the world's plant life. The soil water, or the "soil solution," contains silicon, mainly as silicic acid, H4SiO4, at 0.1-0.6 mM--concentrations on the order of

Pulse electrochemical meso/micro/nano ultraprecision machining technology.

Jeong Min Lee et al.

Journal of nanoscience and nanotechnology, 13(11), 7741-7744 (2013-11-20)

This study demonstrated meso/micro/nano-ultraprecision machining through electrochemical reactions using intermittent DC pulses. The experiment focused on two machining methods: (1) pulse electrochemical polishing (PECP) of stainless steel, and (2) pulse electrochemical nano-patterning (PECNP) on a silicon (Si) surface, using atomic

Deliberations and evaluations of the approaches, endpoints and paradigms for dietary recommendations of the other trace elements.

E O Uthus et al.

The Journal of nutrition, 126(9 Suppl), 2452S-2459S (1996-09-01)

Circumstantial evidence suggests that aluminum, arsenic, bromine, cadmium, germanium, lead, lithium, nickel, rubidium, silicon, tin and vanadium are essential. The evidence is most compelling for arsenic, nickel, silicon and vanadium. The estimated daily dietary intakes for these elements are arsenic

Measurement of immune markers in the serum and cerebrospinal fluid of multiple sclerosis patients during clinical remission.

C E Shaw et al.

Journal of neurology, 242(2), 53-58 (1995-01-01)

Magnetic resonance imaging of multiple sclerosis (MS) patients often shows active inflammatory lesions despite clinical remission. No immunological marker of disease activity has been identified in these patients. Concentrations of neopterin, interleukin-2 (IL-2), soluble interleukin-2 receptor (sIL-2R) and tumour necrosis

Amino acids and biogenic amines in cerebrospinal fluid of patients with Parkinson's disease.

S Engelborghs et al.

Neurochemical research, 28(8), 1145-1150 (2003-07-02)

To study changes in amino acid metabolism and biogenic amines in Parkinson's disease, we set up a prospective study and measured biogenic amines, their main metabolites, and 22 different amino acids, in cerebrospinal fluid of Parkinson's disease patients (n =

Chemistry challenges in lead optimization: silicon isosteres in drug discovery.

Graham A Showell et al.

Drug discovery today, 8(12), 551-556 (2003-06-25)

During the lead optimization phase of drug discovery projects, the factors contributing to subsequent failure might include poor portfolio decision-making and a sub-optimal intellectual property (IP) position. The pharmaceutical industry has an ongoing need for new, safe medicines with a

A novel method to fabricate silicon tubular gratings with broadband antireflection and super-hydrophobicity.

Yang Gao et al.

Journal of nanoscience and nanotechnology, 14(6), 4469-4474 (2014-04-18)

We have developed a novel method to fabricate micro/nano structure based on the coherent diffraction lithography, and acquired periodic silicon tubular gratings with deep nano-scale tapered profiles at the top part. The optical properties of these tubular gratings were similar

Folate and methylation status in relation to phosphorylated tau protein(181P) and beta-amyloid(1-42) in cerebrospinal fluid.

Rima Obeid et al.

Clinical chemistry, 53(6), 1129-1136 (2007-03-27)

Increased plasma total homocysteine (tHcy) is a risk factor for neurological diseases, but the underlying pathophysiology has not been adequately explained. We evaluated concentrations of tHcy, S-adenosyl homocysteine (SAH), S-adenosyl methionine (SAM), folate, and vitamin B(12) in cerebrospinal fluid (CSF)

1/5