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Olivier Autin et al.
Water research, 47(6), 2041-2049 (2013-02-14)
The impact of background constituents on the degradation of trace levels of micropollutants by two advanced oxidation processes: UV/H₂O₂ and UV/TiO₂ was studied. Experimental results demonstrated that the background scavenging rate rather than the concentration of micropollutant controls the required
Nina Baumjohann et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 32(9), 1552-1560 (2015-08-11)
During storage, acetaldehyde migration from polyethylene terephthalate (PET) bottles can affect the quality of mineral water even in the low µg l(-1) range negatively, as it features a fruity or plastic-like off-flavour. For a sensitive and fast analysis of acetaldehyde
Helene Hopfer et al.
Molecules (Basel, Switzerland), 20(5), 8453-8483 (2015-05-20)
Twenty-seven commercial Californian Cabernet Sauvignon wines of different quality categories were analyzed with sensory and chemical methods. Correlations between five quality proxies-points awarded during a wine competition, wine expert scores, retail price, vintage, and wine region-were correlated to sensory attributes
Taichi Yamazaki et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 31(6), 463-468 (2015-06-13)
Acetaldehyde is regulated as a toxic substance in various fields, and the method for monitoring or analysis of acetaldehyde is important. However, handling is difficult because of the high reactivity and low boiling point of acetaldehyde. Therefore, a reference material
Nikoline Borgermann et al.
The EMBO journal, 38(8) (2019-03-28)
DNA-protein crosslinks (DPCs) are highly cytotoxic lesions that obstruct essential DNA transactions and whose resolution is critical for cell and organismal fitness. However, the mechanisms by which cells respond to and overcome DPCs remain incompletely understood. Recent studies unveiled a
Jinjing Wang et al.
Applied biochemistry and biotechnology, 169(3), 1016-1025 (2013-01-09)
Higher acetaldehyde concentration in beer is one of the main concerns of current beer industry in China. Acetaldehyde is always synthesized during beer brewing by the metabolism of yeast. Here, using ethanol as the sole carbon source and 4-methylpyrazole as
Robert Budinsky et al.
Environmental and molecular mutagenesis, 54(9), 755-768 (2013-09-17)
Vinyl acetate monomer (VAM) produced rat nasal tumors at concentrations in the hundreds of parts per million. However, VAM is weakly genotoxic in vitro and shows no genotoxicity in vivo. A European Union Risk Assessment concluded that VAM's hydrolysis to
Allison C Hoffman et al.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 15(3), 622-632 (2012-09-20)
This review identified published animal studies evaluating the possible abuse potential of acetaldehyde, nornicotine, cotinine, and anabasine based on five commonly used paradigms. These include their effects on midbrain dopamine (DA) levels, drug discrimination and substitution for known drugs of
Valeria Romanazzi et al.
Environmental toxicology and pharmacology, 36(2), 378-383 (2013-06-05)
Acetaldehyde (AA) is the main metabolic product in ethanol metabolism, although it can also derive from sources of airborne pollution. As a typical aldehyde, AA is able to react with a variety of molecular targets, including DNA and protein. This
Rubén del Barrio-Galán et al.
Food chemistry, 179, 116-126 (2015-02-28)
The effect of high levels of the polysaccharide Saccharomyces cerevisiae yeast strain (HPS) and another conventional yeast strain (FERM) on the polysaccharide and phenolic composition of Syrah red wines during alcoholic fermentation and subsequent aging on lees, with or without
Hyeong-Geug Kim et al.
World journal of gastroenterology, 20(42), 15703-15714 (2014-11-18)
To evaluate protective effects of Chunggan extract (CGX), a traditional herbal formula, under 4 wk of alcohol consumption-induced liver injury. Male Sprague-Dawley Rats were orally administered 30% ethanol daily for 4 wk with or without CGX. The pharmaceutical properties were
Tetsushi Azuma et al.
Journal of plant physiology, 170(13), 1158-1164 (2013-04-18)
Gravitropic curvature of pulvini of wheat and oat stem segments gradually declined with decreasing atmospheric O₂ concentration and was almost completely blocked under anoxia, whereas that of rice stem segments was enhanced under hypoxia and anoxia. Anoxia substantially increased the
Takuya Kitamura et al.
The Biochemical journal, 465(1), 79-87 (2014-10-07)
Aldehyde dehydrogenases (ALDHs) catalyse the conversion of toxic aldehydes into non-toxic carboxylic acids. Of the 21 ALDHs in mice, it is the ALDH3 family members (ALDH3A1, ALDH3A2, ALDH3B1, ALDH3B2 and ALDH3B3) that are responsible for the removal of lipid-derived aldehydes.
Tengfei Jiang et al.
Journal of colloid and interface science, 405, 242-248 (2013-06-20)
In this study, the p-Cu2O/n-Cu2O homojunction film was prepared by a simple two-step electrodeposition method. The photoinduced charge transfer process in p-Cu2O/n-Cu2O homojunction film was studied using surface photovoltage technique. Then, the p-Cu2O/n-Cu2O homojunction film was assembled into a photoelectric
Iu E Morozov et al.
Sudebno-meditsinskaia ekspertiza, 45(2), 35-40 (2002-06-18)
The content of ethanol and acetaldehyde in the limbic cortex and reticular formation of the brain was measured by gas-liquid chromatography in lethal ethanol poisoning. The content of acetaldehyde was significantly increased in the gyrus cinguli of the brain. Lethal
Sarah E Frey et al.
Journal of the Air & Waste Management Association (1995), 64(11), 1251-1259 (2014-12-17)
A survey of key indoor air quality (IAQ) parameters and resident health was carried out in 72 apartments within a single low-income senior housing building in Phoenix, Arizona. Air sampling was carried out simultaneously with a questionnaire on personal habits
Tommaso Mello et al.
Molecular aspects of medicine, 29(1-2), 17-21 (2008-01-01)
Alcohol abuse is one of the major causes of liver fibrosis worldwide. Although the pathogenesis of liver fibrosis is a very complex phenomenon involving different molecular and biological mechanisms, several lines of evidence established that the first ethanol metabolite, acetaldehyde
S E Frey et al.
Indoor air, 25(2), 210-219 (2014-06-13)
To investigate the impacts of an energy efficiency retrofit, indoor air quality and resident health were evaluated at a low-income senior housing apartment complex in Phoenix, Arizona, before and after a green energy building renovation. Indoor and outdoor air quality
Mashiko Setshedi et al.
Oxidative medicine and cellular longevity, 3(3), 178-185 (2010-08-19)
Chronic alcohol abuse causes liver disease that progresses from simple steatosis through stages of steatohepatitis, fibrosis, cirrhosis, and eventually hepatic failure. In addition, chronic alcoholic liver disease (ALD), with or without cirrhosis, increases risk for hepatocellular carcinoma (HCC). Acetaldehyde, a
Marlena K Sheridan et al.
Food chemistry, 177, 17-22 (2015-02-11)
Wine tannins undergo modifications during fermentation and storage that can decrease their perceived astringency and increase color stability. Acetaldehyde acts as a bridging compound to form modified tannins and polymeric pigments that are less likely to form tannin-protein complexes than
W G Brydon et al.
European journal of gastroenterology & hepatology, 8(2), 117-123 (1996-02-01)
To assess the reliability of serum 7 alpha-hydroxy-4-cholesten-3-one (7 alpha-3ox-C) in the differential diagnosis of bile acid induced diarrhoea by comparison with 75selenohomocholyltaurine whole body retention (SeHCAT WBR). One hundred and sixty-four patients with chronic diarrhoea were investigated prospectively in
Hyo-Jung Kwon et al.
Hepatology (Baltimore, Md.), 60(1), 146-157 (2014-02-05)
Aldehyde dehydrogenase 2 (ALDH2) is the major enzyme that metabolizes acetaldehyde produced from alcohol metabolism. Approximately 40-50% of East Asians carry an inactive ALDH2 gene and exhibit acetaldehyde accumulation after alcohol consumption. However, the role of ALDH2 deficiency in the
Alexandre J Parent et al.
The journal of pain : official journal of the American Pain Society, 16(5), 436-444 (2015-02-11)
Descending pain inhibition is an endogenous pain control system thought to depend partially on the activation of bulbospinal monoaminergic pathways. Deficits in descending pain inhibition have been reported in numerous human chronic pain conditions, but there is currently no consensus
H Matsuse et al.
The Journal of allergy and clinical immunology, 108(5), 715-719 (2001-11-03)
We have previously reported that alcohol-induced asthma in Japanese patients is caused by increased blood acetaldehyde concentration resulting from abnormalities of acetaldehyde dehydrogenase 2 (ALDH2) enzyme activity on the basis of ALDH2 genotype differences. The purpose of the present study
Hsu-Sheng Yu et al.
Chemico-biological interactions, 188(3), 367-375 (2010-09-04)
Epidemiological studies have identified chronic alcohol consumption as a significant risk factor for cancers of the upper aerodigestive tract, including the oral cavity, pharynx, larynx and esophagus, and for cancer of the liver. Ingested ethanol is mainly oxidized by the
Carsten Dingels et al.
Biomacromolecules, 14(2), 448-459 (2012-12-22)
Poly(ethylene glycol) (PEG) with acid-sensitive moieties gained attention particularly for various biomedical applications, such as the covalent attachment of PEG (PEGylation) to protein therapeutics, the synthesis of stealth liposomes, and polymeric carriers for low-molecular-weight drugs. Cleavable PEGs are favored over
Zuquan Weng et al.
Toxicology, 311(3), 107-114 (2013-07-03)
Ethyl tertiary butyl ether (ETBE) is biofuel additive recently used in Japan and some other countries. Limited evidence shows that ETBE has low toxicity. Acetaldehyde (AA), however, as one primary metabolite of ETBE, is clearly genotoxic and has been considered
T W Boyden et al.
European journal of pharmacology, 70(4), 571-576 (1981-04-09)
Utilizing a method for perfusion of the in vivo isolated canine testis we have examined basal and human chorionic gonadotropin (hGC)-stimulated testosterone production of testes acutely exposed to ethanol and acetaldehyde. Ethanol infused at concentrations of 0.2 g/dl to 0.6
Richard J Albertini
Critical reviews in toxicology, 43(8), 671-706 (2013-08-30)
Vinyl acetate monomer (VAM) is a site-of-contact carcinogen in rodents. It is also DNA reactive and mutagenic, but only after its carboxylesterase mediated conversion to acetaldehyde (AA), a metabolic reaction that also produces acetic acid and protons. As VAM's mutagenic
Susumu Higuchi et al.
Annals of the New York Academy of Sciences, 1025, 472-480 (2004-11-16)
Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase-2 (ALDH2) play central roles in the metabolism of ethanol and its metabolite, acetaldehyde, in the liver. In ADH2, one nucleotide replacement causes either a super-active beta 2 subunit encoded by the ADH2*2 allele or
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