CN
Search Within
D2600000
应用筛选条件
关键词:'D2600000'
显示 1-30 共 39 条结果 关于 "D2600000" 范围 论文
David C Sheridan et al.
Pediatric emergency care, 28(12), 1293-1296 (2012-11-29)
Limited progress has been made in the past decade for abortive treatment of migraine headache in the pediatric emergency department (PED). Propofol, a general anesthetic, has been reported to be effective in the treatment of refractory headaches in adults at
Paige M Evans et al.
American journal of veterinary research, 73(12), 1983-1986 (2012-11-28)
To evaluate the effects of oral administration of diphenhydramine on pupil diameter, intraocular pressure (IOP), tear production, tear film quality, corneal sensitivity, and conjunctival goblet cell density (GCD) in clinically normal adult dogs. 12 healthy adult dogs. All dogs received
Ayako Nonaka et al.
Brain research, 1493, 19-26 (2012-11-28)
Antihistamines are widely used to treat allergy symptoms. First-generation antihistamines have adverse effects on the central nervous system (CNS), such as hypnotic and amnesic effects, whereas second-generation antihistamines have poor brain penetration, and therefore, have fewer CNS-related adverse effects. Memory
Akira Takahara et al.
Journal of pharmacological sciences, 120(3), 165-175 (2012-10-11)
Cloperastine is an antitussive drug, which can be received as an over-the-counter cold medicine. The chemical structure of cloperastine is quite similar to that of the antihistamine drug diphenhydramine, which is reported to inhibit hERG K⁺ channels and clinically induce
Chenxi Wu et al.
Ecotoxicology and environmental safety, 85, 104-109 (2012-08-28)
The plant uptake of emerging organic contaminants such as pharmaceuticals and personal care products (PPCPs) is receiving increased attention. Biosolids from municipal wastewater treatment have been previously identified as a major source for PPCPs. Thus, plant uptake of PPCPs from
Donita D Lightner et al.
Journal of pediatric hematology/oncology, 35(7), e274-e275 (2013-09-26)
Mannitol is used for increased intracranial pressure and prevention of nephrotoxicity. We present a case report of a patient who experienced an anaphylactic response to mannitol and review the literature.
Tzu-Kai Lin et al.
The Journal of investigative dermatology, 133(2), 469-478 (2012-09-28)
Systemic antagonists of the histamine type 1 and 2 receptors (H1/2r) are widely used as anti-pruritics and central sedatives, but demonstrate only modest anti-inflammatory activity. Because many inflammatory dermatoses result from defects in cutaneous barrier function, and because keratinocytes express
Andrew Curtright et al.
PloS one, 10(1), e0116766-e0116766 (2015-01-15)
Acute and chronic pain conditions are often debilitating, inflicting severe physiological, emotional and economic costs and affect a large percentage of the global population. However, the development of therapeutic analgesic agents based primarily on targeted drug development has been largely
Erik W Gunderson et al.
Journal of addiction medicine, 7(3), 163-168 (2013-06-05)
In this report, we describe a case of intranasal "bath salts"-associated psychosis. Symptoms developed during a 3-week binge and were potentially exacerbated by oral diphenhydramine taken for insomnia. The clinical case conference includes expert discussion from 3 disciplines: emergency medicine
Marc Marino et al.
Journal of neuroscience methods, 211(1), 1-10 (2012-09-14)
Pruritus, the sensation of itch, which evokes reflex scratching behavior, has a diverse etiology. Because of its clinical significance, mechanisms of pruriception are an important topic. In the present work we describe and validate a paw motion detector (PMD) system.
Suddent onset: be prepared to treat anaphylactic incidents before it's too late.
Rick Rod
JEMS : a journal of emergency medical services, 37(8), 60-64 (2012-11-30)
V B Shevchenko et al.
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 84(4), 74-78 (2012-09-06)
The fluorescence spectra of the porous silicon modified by water solutions of biologically active materials and materials of biological origin are recorded as well as the fluorescence spectra of the porous silicon modified by lecithin monolayers grown on the surface
Edward Topp et al.
The Science of the total environment, 439, 136-140 (2012-10-16)
The widely used antihistamine diphenhydramine is present in municipal biosolids, and is detected in runoff from agricultural land fertilized with biosolids. In the present study the kinetics and major pathways of diphenhydramine dissipation in a loam, sandy loam, and clay
Eugene W Schwilke et al.
Journal of forensic sciences, 51(5), 1191-1198 (2006-10-05)
We have previously reported on patterns of drug and alcohol use in fatally injured drivers in Washington State. Here we revisit that population to examine how drug use patterns have changed in the intervening 9 years. Blood and serum specimens
Mohammed Maniruzzaman et al.
International journal of pharmaceutics, 443(1-2), 199-208 (2012-12-25)
The purpose of the study was to investigate and identify the interactions within solid dispersions of cationic drugs and anionic polymers processed by hot-melt extrusion (HME) technique. Propranolol HCl (PRP) and diphenhydramine HCl (DPD) were used as model cationic active
A new hydrophilic interaction liquid chromatographic (HILIC) procedure for the simultaneous determination of pseudoephedrine hydrochloride (PSH), diphenhydramine hydrochloride (DPH) and dextromethorphan hydrobromide (DXH) in cough-cold formulations.
Ali S M, et al.
Journal of Pharmaceutical and Biomedical Analysis, 43(1), 158-167 (2007)
Suzanne Doyon et al.
Clinical toxicology (Philadelphia, Pa.), 51(10), 941-948 (2013-10-18)
Deaths from overdose of acetaminophen (APAP) combination medications are reported, yet the individual ingredients are not well examined as individual putative causes of death. To examine the individual contribution of APAP or other ingredient(s) to fatalities resulting from ingestion of
A D Rollstin et al.
Clinical toxicology (Philadelphia, Pa.), 51(1), 50-53 (2012-12-01)
There are few reports of acetaminophen overdose in hypothermic patients and even fewer reports describing profound hypothermia. The kinetics, risk of hepatotoxicity, and the possible dose adjustments to N-acetylcysteine (NAC) therapy are not known in this setting. A 37-year-old female
Makiko Kido-Nakahara et al.
The Journal of clinical investigation, 124(6), 2683-2695 (2014-05-09)
In humans, pruritus (itch) is a common but poorly understood symptom in numerous skin and systemic diseases. Endothelin 1 (ET-1) evokes histamine-independent pruritus in mammals through activation of its cognate G protein-coupled receptor endothelin A receptor (ETAR). Here, we have
Andreas Papassotiropoulos et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(46), E4369-E4374 (2013-10-23)
In the last decade there has been an exponential increase in knowledge about the genetic basis of complex human traits, including neuropsychiatric disorders. It is not clear, however, to what extent this knowledge can be used as a starting point
Akira Nakagawachi et al.
Masui. The Japanese journal of anesthesiology, 61(9), 988-992 (2012-09-28)
Laparoscopic percutaneous extraperitoneal closure (LPEC), introduced as an alternative to a conventional open inguinal hernia repair in children, has shown a higher incidence of postoperative vomiting (POV). The aim of this study was to examine whether a prophylactic use of
Andrée E Gravel et al.
Biochimica et biophysica acta, 1828(6), 1494-1502 (2013-03-12)
The human ether-a-go-go-related gene (hERG) voltage-gated K(+) channels are located in heart cell membranes and hold a unique selectivity filter (SF) amino acid sequence (SVGFG) as compared to other K(+) channels (TVGYG). The hERG provokes the acquired long QT syndrome
What is your diagnosis? Intracranial parasitic migration.
Allison B Ward et al.
Journal of the American Veterinary Medical Association, 241(6), 693-695 (2012-09-06)
J Rojas et al.
Die Pharmazie, 67(7), 595-597 (2012-08-15)
Microcrystalline cellulose II (MCCII) is a different allomorph of MCC that can be used as a filler and a disintegrant for direct compression. MCCII was studied as new pelletization aid with the aim to prepare pellets with a faster drug
Takashi Koyanagi et al.
Xenobiotica; the fate of foreign compounds in biological systems, 44(10), 893-901 (2014-03-22)
1. The pharmacokinetics of acetaminophen (marker of gastric emptying), antipyrine (marker of hepatic metabolic activity and total body water), diazepam (lipophilic and highly distributed), diphenhydramine (hepatic blood flow-limited and alpha-1 acid glycoprotein bound) and ofloxacin (renally eliminated) were evaluated in
Xintao Wang et al.
Biomedical chromatography : BMC, 27(3), 371-376 (2012-08-16)
A sensitive, rapid and selective ultra-performance liquid chromatography-tandem mass spectrometric (UPLC-MS/MS) method was developed for the determination and pharmacokinetic study of domperidone in human plasma. Diphenhydramine was used as the internal standard. Plasma sample pretreatment involved a one-step liquid-liquid extraction
Separation and determination of pseudoephedrine, dextromethorphan, diphenhydramine and chlorpheniramine in cold medicines by nonaqueous capillary electrophoresis.
Dong Y, et al.
Journal of Pharmaceutical and Biomedical Analysis, 39(1-2), 285-289 (2005)
Jeffery R Meinertz et al.
Bulletin of environmental contamination and toxicology, 89(5), 970-974 (2012-09-08)
Freshwater mussel populations are declining in North America. Potential anthropogenic stressors may be contributing to the declines and may include the continual presence of pharmaceutical compounds in waterways. Diphenhydramine hydrochloride (DH) is an over-the-counter antihistamine marketed under several name brand
Jung Yeon Kim et al.
Biomedical chromatography : BMC, 29(3), 465-474 (2014-08-01)
The purpose of this study was to develop and validate an ultra-performance liquid chromatography method for simultaneous analysis of 20 antihistamines (illegal additives) in dietary supplements. The limits of detection and quantitation of the method ranged from 1.5 to 2.5
Don W Coulter et al.
Anti-cancer drugs, 24(4), 415-421 (2013-01-19)
A pediatric study has established a maximum tolerated dose (MTD) for temsirolimus (Tem) of more than 150 mg/m intravenously/week. A phase I trial was conducted to establish the MTD for Tem in combination with valproic acid (VPA) in children and
1/2