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Analytical chemistry

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使用超纯水按USP法测定元素杂质
药品中的元素杂质对人健康有害并受到监管。Milli-Q®超纯水系统可满足对药品痕量元素的分析要求。
红外光谱表
红外光谱表是在红外光谱分析中使用的图表。该表列出了红外光谱的频率范围、官能团的振动和吸收条带外观。
HPLC故障排除指南
识别、纠正常见HPLC问题,恢复色谱柱性能。通过色谱图示例,获取解决峰相关问题(峰分裂、峰拖尾、峰前延等)、保留时间、吹扫噪声及分离度下降问题排查帮助。
用在药品微量元素杂质评估过程中的超纯水
在药品开发和生产的各个阶段,必须监测和控制其中的元素杂质含量。建议使用 Milli-Q® 纯水系统产出的超纯水进行 ICP-MS 和 ICP-OES 微量元素分析。
绿色化学原则
了解绿色化学的原则,以及我们公司如何通过专门的、可持续预防计划来帮助您减少化学相关物质对人类健康和环境的危害。
Proline Derivatization and Enantioresolution by Chiral GC
Amino acids are building blocks of peptides and proteins. Enantiomeric separation of these molecules can be performed through chromatography by chiral stationary phases. This article describes the chiral GC analysis of one amino acid, proline, after achiral derivatization.
Syringe Filters
Answers to common syringe filter selection questions, such as sterile vs non-sterile, how to use, membrane and housing types, and pore size.
Analysis of Acylcarnitines in Dried Blood Spots (DBS) Samples by FIA-MS/MS
In this article we provide a complete workflow of quantification and identification of acylcarnitines in dried blood spots (DBS) using stable isotope-labeled (SIL) acylcarnitines CRMs by FIA-MS/MS.
Ultrapure Water to Assess Elemental Impurities per USP
Elemental impurities in pharmaceutical drugs present a risk to human health and are regulated. Milli-Q® ultrapure water purification systems comply with the requirements for trace element analyses.
LC-MS Analysis of Hormones in Tap Water
Milli-Q® ultrapure water systems deliver water free of organic contaminants , including hormones present in a lab's tap water, making it suitable for the most sensitive LC-MS/MS analyses.
Characterization of Stable Isotope Caffeine as Reference Material for Isotope Dilution Mass Spectrometry
This technique is based on the direct proportionality of mass fraction ratio and signal intensity ratio of the natural isotope and the C-13 labeled caffeine.
Solution with 17 Amino Acids as TraceCERT® Certified Reference Material
Technical article on "Solution with 17 Amino Acids as TraceCERT® Certified Reference Material"
Replace Classical Liquid-Liquid Extractions with EXtrelut® NT
Simplify your liquid-liquid extractions with our emulsion-free supported-liquid extraction (SLE) single step solution.
Quantification of Bitter Acids in Hops by Thin Layer Chromatography
HPTLC separation followed by UV detection of the bitter acid content in various hop samples.
Syringe Filters for Chromatography
Syringe filter selection guide for HPLC, UHPLC, and Ion Chromatography using pore size, filter diameter, chemical compatibility, analyte binding, and extractables.
Drospirenone Assay - USP Monograph
Determination of the progestin medication, Drospirenone, using Purospher® STAR RP-18e Hibar® HPLC column and meeting the system suitability criteria as described in the USP monograph.
ChemisTwin® Portal FAQ
Learn about ChemisTwin® Portal, an online analytical spectra interpretation tool. Discover its NMR lab benefits, workflow integration, and user responsibilities. Explore dRMs, algorithm accuracy, data formats, subscription possibilities, and more.
Ultrapure Water to Assess Trace Element Impurities in Pharmaceuticals
Elemental impurities in pharmaceutical products must be monitored and controlled at all stages of development and production. Ultrapure water produced by a Milli-Q® water system is recommended for ICP-MS and ICP-OES trace element analyses.
Determination of Stevioside and Rebaudioside A in Stevia leaves, beverages and food additives using HPTLC-MS
HPTLC-MS was used to analyze stevioside and rebaudioside in artificial sweeteners, stevia plants, cola and isotonic drinks with a minimum of sample preparation.
Supel™-Select Polymeric SPE
Supel-Select HLB SPE - a hydrophilic modified styrene based polymer developed for the solid phase extraction of a broad range of compounds from aqueous samples.
Synthetic Cannabinoid Analysis
A large variety of cannabinoid drug standards, along with an HPLC method with the Supelco Ascentis® Express RP-Amide column, are presented in this article.
Rapid Analysis of Caffeinated Energy Drinks by HPLC on Ascentis® Express
The sample complexity makes it important to use highly-efficient, highly-selective phases and columns that are compatible with different detection systems to maximize the information from HPLC experiments. Ascentis Express Fused-Core® columns meet these requirements.
Supelco Preparative HPLC products for Pharmaceutical Development and Production
Supelco Preparative HPLC products for Pharmaceutical Development and Production
Ultrapure Water for LC MS Biomedical Analyses
This study assesses the suitability of ultrapure water from a Milli-Q® water system for sensitive LC-MS analyses of hormones.
Green Chemistry Principles
Understand green chemistry principles and our company's sustainable initiatives to minimize chemical-related environmental impact and human health risks.
HPLC Troubleshooting Guide
Correct common HPLC issues to restore column performance, addressing peak problems, retention time, noise, and resolution with chromatograms.