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Kohei Takeshita et al.
Nature structural & molecular biology, 21(4), 352-357 (2014-03-04)
The voltage-gated proton channel Hv1 (or VSOP) has a voltage-sensor domain (VSD) with dual roles of voltage sensing and proton permeation. Its gating is sensitive to pH and Zn(2+). Here we present a crystal structure of mouse Hv1 in the
Jun-Hui Choi et al.
Journal of bioscience and bioengineering, 118(4), 372-377 (2014-04-22)
A thrombolytic protease named kitamase possessing anticoagulant property was purified from edible and medicinal plant Aster yomena (Kitam.) Honda. Kitamase showed a molecular weight of 50 kDa by SDS-PAGE and displayed a strong fibrin zymogram lysis band corresponding to the similar
Yang Liu et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 13(23), 6667-6673 (2007-05-31)
Well-aligned zinc oxide microrod and microtube arrays with high aspect ratios were fabricated on zinc foil by a simple solution-phase approach in an aqueous solution of ethylenediamine (en). The shape of the ZnO microstructures can be easily modulated from rods
R K Sharma et al.
Journal of environmental biology, 35(4), 727-732 (2014-07-10)
The present study investigates the responses of Indian palak (Beta vulgaris L. cv. All Green H1) exposed to cadmium (Cd) and zinc (Zn) at growth, biochemical and physiological levels. The results revealed that Cd and Zn accumulation was higher in
Jungsoo Kim et al.
Environmental monitoring and assessment, 187(1), 4124-4124 (2014-11-21)
Cadmium (Cd), lead (Pb), manganese (Mn), zinc (Zn), and iron (Fe) concentrations were measured in the prey and liver of grey heron (Ardea cinerea) and black-crowned night heron (Nycticorax nycticorax) chicks (24-26 days after hatching) at the Pyeongtaek colony, Korea
William F Walkenhorst et al.
Biochimica et biophysica acta, 1838(9), 2234-2242 (2014-05-21)
Recently we described the pH dependence of activity for a family of cationic antimicrobial peptides (CAMPs) selected from a combinatorial library. In the current work we report on the effects of toxic ions (Cu(2+), Zn(2+), and F(-)) and the chelator
Lumbini R Yadav et al.
Biochemical and biophysical research communications, 450(1), 283-288 (2014-06-14)
Zinc finger transcription regulatory proteins play crucial roles in cell-cycle regulation, DNA damage response and tumor genesis. Human ZBRK1 is a zinc-finger transcription repressor protein, which recognizes double helical DNA containing consensus sequences of 5'GGGXXXCAGXXXTTT3'. In the present study, we
M Pogrzeba et al.
Environmental monitoring and assessment, 187(1), 4120-4120 (2014-11-10)
Many years of heavy industrial processes in the Upper Silesian Industrial Region in Poland (ore flotation, metal smelting and battery scrap processing) have resulted in lead, zinc and cadmium pollution of the air and soil. The most significant issues stem
Dai Mizuno et al.
International journal of molecular sciences, 14(11), 22067-22081 (2013-11-12)
Zinc (Zn) is an essential trace element that is abundantly present in the brain. Despite its importance in normal brain functions, excess Zn is neurotoxic and causes neurodegeneration following transient global ischemia and plays a crucial role in the pathogenesis
Umi Fahmida et al.
Food and nutrition bulletin, 35(4 Suppl), S174-S179 (2015-02-03)
Affordable, locally contextual complementary feeding recommendations (CFRs) that take into account cultural diversity and differences in food availability will be more likely to result in long-term improvements in complementary feeding practices than general recommendations. More objective approaches, such as linear
Y Z Zhu et al.
Life sciences, 102(1), 36-40 (2014-03-13)
The aim of this study was to determine the effects of sub-chronic aluminum chloride (AlCl3) on spermatogenesis and testicular enzymatic activity in male rats. Forty Wistar male rats were randomly divided into four groups: control group (CG, 0), low-dose group
Saeed Akhtar
Journal of health, population, and nutrition, 31(2), 139-149 (2013-08-13)
This article attempts to highlight the prevalence of zinc deficiency and its health and economic consequences in South Asian developing countries and to shed light on possible approaches to combating zinc deficiency. A computer-based search was performed on PubMed, Google
Hongqin Liu et al.
ACS applied materials & interfaces, 1(9), 2086-2091 (2010-04-02)
Zinc, silicon, and steel superhydrophobic surfaces were prepared by a simple solution-immersion technique. In the case of zinc, the method consists of dipping of the substrate in a prehydrolyzed methanol solution of 1H,1H,2H,2H-(perfluorooctyl)trichlorosilane [CF(3)(CF(2))(5)(CH(2))(2)SiCl(3), PFTS] for 24 h at 50
Sanjukta Subudhi et al.
Chemosphere, 113, 116-124 (2014-07-30)
A bioflocculant-producing bacterial isolate designated as 'TERI-IASST N' was isolated from activated sludge samples collected from an oil refinery. This isolate demonstrated maximum bioflocculation activity (74%) from glucose among 15 different bioflocculant-producing bacterial strains isolated from the sludge samples and
Huibo Chen et al.
Nanoscale research letters, 5(3), 570-575 (2009-01-01)
We reported the optical and wettability properties of aligned zinc oxide micro/nanotube arrays, which were synthesized on zinc foil via a simple hydrothermal method. As-synthesized ZnO micro/nanotubes have uniform growth directions along the [0001] orientations with diameters in the range
Misu Sanson et al.
Nucleic acids research, 43(1), 418-432 (2014-12-17)
Altering zinc bioavailability to bacterial pathogens is a key component of host innate immunity. Thus, the ability to sense and adapt to the alterations in zinc concentrations is critical for bacterial survival and pathogenesis. To understand the adaptive responses of
Dong-Woo Kim et al.
Journal of nanoscience and nanotechnology, 14(6), 4632-4638 (2014-04-18)
Bis(alkylimidazole) complexes of zinc, (RIm)2ZnX2, were prepared by a metal insertion reaction. The synthesized (RIm)2ZnX2 exhibited good catalytic performance during synthesis of glycerol carbonate (GC) from glycerol and urea. (HEIm)2ZnCl2 with a hydroxyl group exhibited the highest GC yield during
Ronny Lehneck et al.
The FEBS journal, 281(7), 1759-1772 (2014-02-11)
Carbonic anhydrases (CAs) are metalloenzymes catalyzing the reversible hydration of carbon dioxide to bicarbonate (hydrogen carbonate) and protons. CAs have been identified in archaea, bacteria and eukaryotes and can be classified into five groups (α, β, γ, δ, ζ) that
Pseudomonas aeruginosa elastase disrupts the cortisol-binding activity of corticosteroid-binding globulin.
Simard M, Hill LA, Underhill CM, et al.
Endocrinology, 155(8), 2900-2908 (2014)
Zhelong Xu et al.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 26(6), 863-878 (2013-08-29)
As an important trace element, zinc is required for the normal cellular structure and function, and impairment of zinc homeostasis is associated with a variety of health problems including cardiovascular disease. Zinc homeostasis is regulated through zinc transporters, zinc binding
Liangzhong Lim et al.
Biochimica et biophysica acta, 1848(1 Pt A), 1-7 (2014-10-14)
Mutations in superoxide dismutase 1 (SOD1) cause familial amyotrophic lateral sclerosis (FALS), while wild-type SOD1 has been implicated in sporadic ALS (SALS). SOD1 mutants are now recognized to acquire one or more toxicities that include their association with mitochondrial and
K Ryan Wessells et al.
The Journal of nutrition, 144(8), 1204-1210 (2014-05-23)
Plasma zinc concentration (PZC) is a recommended biomarker to assess zinc status and the risk of zinc deficiency in populations. However, the relation between PZC and clinical signs of zinc deficiency remains uncertain. These analyses were conducted to evaluate the
Tasuku Ito et al.
Biochemical and biophysical research communications, 447(1), 32-37 (2014-04-01)
Enzymes acting on β-linked arabinofuranosides have been unknown until recently, in spite of wide distribution of β-l-arabinofuranosyl oligosaccharides in plant cells. Recently, a β-l-arabinofuranosidase from the glycoside hydrolase family 127 (HypBA1) was discovered in the newly characterized degradation system of
Judith Ernst et al.
Food and nutrition bulletin, 35(4 Suppl), S198-S204 (2015-02-03)
Preliminary evidence suggests that improved nutrition early in HIV infection may delay progression to AIDS and delay the initiation or improve the effectiveness of antiretroviral drug therapy. There are few studies that evaluate food-based interventions in drug-naïve, HIV-infected women and
Deborah R Morris et al.
Current opinion in clinical nutrition and metabolic care, 16(6), 708-711 (2013-08-16)
In light of the recent recognition that even mild forms of traumatic brain injury (TBI) can lead to long-term cognitive and behavioral deficits, this review examines recent data on the neuroprotective and neurotoxic roles of zinc after brain injury. Data
Attila Lehotzky et al.
Biochimica et biophysica acta, 1852(1), 83-91 (2014-12-03)
Tubulin Polymerization Promoting Protein/p25 (TPPP/p25), a neomorphic moonlighting protein displaying both physiological and pathological functions, plays a crucial role in the differentiation of the zinc-rich oligodendrocytes, the major constituent of myelin sheath; and it is enriched and co-localizes with α-synuclein
M Munirul Islam et al.
The Journal of nutrition, 144(5), 771-776 (2014-03-07)
Information is needed on breast milk zinc concentration and amount of zinc transferred to the infant in relation to the time since birth for both appropriate-for-gestational-age (AGA) and small-for-gestational-age (SGA) infants. Breast milk zinc concentration and total milk volume were
Venus Singh Mithu et al.
The Journal of biological chemistry, 289(16), 11122-11131 (2014-03-07)
Amyloid β (Aβ) fibrillar deposits in the brain are a hallmark of Alzheimer disease (AD). Curcumin, a common ingredient of Asian spices, is known to disrupt Aβ fibril formation and to reduce AD pathology in mouse models. Understanding the structural
J Granell
The Journal of sports medicine and physical fitness, 54(2), 232-237 (2014-02-11)
The role of zinc and copper has been shown essential in the scope of physical exercise. The outcomes of the studies about changes in the concentrations of these elements in blood, in physical effort situations, are sometimes discordant and seem
Nathan H Joh et al.
Science (New York, N.Y.), 346(6216), 1520-1524 (2014-12-20)
The design of functional membrane proteins from first principles represents a grand challenge in chemistry and structural biology. Here, we report the design of a membrane-spanning, four-helical bundle that transports first-row transition metal ions Zn(2+) and Co(2+), but not Ca(2+)
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