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Merck
CN

Zinc and myocardial ischemia/reperfusion injury.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine (2013-08-29)
Zhelong Xu, Juan Zhou
摘要

As an important trace element, zinc is required for the normal cellular structure and function, and impairment of zinc homeostasis is associated with a variety of health problems including cardiovascular disease. Zinc homeostasis is regulated through zinc transporters, zinc binding molecules, and zinc sensors. Zinc also plays a critical role in cellular signaling. Studies have documented that zinc homeostasis is impaired by ischemia/reperfusion in the heart and zinc dyshomeostasis may play a role in the pathogenesis of myocardial ischemia/reperfusion injury. Both exogenous and endogenously released zinc may play an important role in cardioprotection against ischemia/reperfusion injury. The goal of this review is to summarize the current understanding of the roles of zinc homeostasis and zinc signaling in myocardial ischemia/reperfusion injury.

材料
Product Number
品牌
产品描述

Sigma-Aldrich
锌, foil, thickness 0.25 mm, 99.9% trace metals basis
Sigma-Aldrich
锌, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.9%, granular
锌, foil, 300x300mm, thickness 0.1mm, as rolled, 99.95+%
Sigma-Aldrich
锌, shot, <12 mm, 99.99% trace metals basis
锌, wire reel, 5m, diameter 1.0mm, 99.99+%
Sigma-Aldrich
锌, shot, 5 mm, 99.999% trace metals basis
锌, foil, 100x100mm, thickness 0.1mm, as rolled, 99.95+%
Sigma-Aldrich
锌, foil, thickness 1.0 mm, 99.99% trace metals basis
锌, foil, 50x50mm, thickness 0.1mm, as rolled, 99.95+%
锌, foil, 1m coil, thickness 0.025mm, as rolled, 99.95+%
锌, foil, 5m coil, thickness 0.125mm, as rolled, 99.95+%
锌, wire reel, 0.5m, diameter 1.0mm, 99.99+%
锌, wire reel, 1m, diameter 1.0mm, 99.99+%
锌, foil, 100x100mm, thickness 0.15mm, as rolled, 99.95+%
锌, foil, 0.5m coil, thickness 0.05mm, as rolled, 99.95+%
锌, wire reel, 25m, diameter 0.125mm, as drawn, 99%
锌, wire reel, 2m, diameter 0.125mm, as drawn, 99%
锌, foil, 150x150mm, thickness 0.15mm, as rolled, 99.95+%
锌, foil, 300x300mm, thickness 2.0mm, as rolled, 99.95+%
锌, wire reel, 10m, diameter 0.125mm, as drawn, 99%
锌, foil, 25x25mm, thickness 0.175mm, as rolled, 99.95+%
锌, foil, 25x25mm, thickness 3mm, as rolled, 99.99+%
锌, foil, 50x50mm, thickness 0.15mm, as rolled, 99.95+%
锌, foil, 8mm disks, thickness 0.01mm, 99.9%
锌, wire reel, 5m, diameter 0.05mm, as drawn, 99%
锌, foil, light tested, 50x50mm, thickness 0.025mm, as rolled, 99.99+%
锌, foil, 2m coil, thickness 0.05mm, as rolled, 99.95+%
锌, wire reel, 10m, diameter 0.25mm, as drawn, 99.99+%
锌, foil, 150x150mm, thickness 0.175mm, as rolled, 99.95+%
锌, wire reel, 0.5m, diameter 1.0mm, 99.999%