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Stanisław Popiel et al.
Analytica chimica acta, 837, 52-63 (2014-07-09)
Novel solid-phase microextraction (SPME) fibres containing methyl, ethyl, butyl acrylate and methacrylate were first prepared by a sol-gel technique and investigated for determination of selected organoarsenic compounds (lewisite, methyldichloroarsine, phenyldichloroarsine, diphenylchloroarsine and triphenylarsine) from water samples. The influence of sorption
Megan E Oest et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 33(3), 334-342 (2014-11-20)
Late-onset fragility fractures are a common complication following radiotherapy for metastatic disease and soft tissue sarcomas. Using a murine hindlimb focal irradiation model (RTx), we quantified time-dependent changes in osteoclasts and mineral apposition rate (MAR). Mice received either a single
Makoto Ishida et al.
Drug development and industrial pharmacy, 40(8), 1054-1064 (2013-06-21)
Abstract The applicability of porous spherical silica (PSS) was evaluated as core particles for pharmaceutical products by comparing it with commercial core particles such as mannitol (NP-108), sucrose and microcrystalline cellulose spheres. We investigated the physical properties of core particles
Marwa Ahmed et al.
Journal of chromatography. A, 1360, 100-109 (2014-08-19)
Single-walled carbon nanotubes were encapsulated into different polymer-based monolithic backbones. The polymer monoliths were prepared via the copolymerization of 20% monomers, glycidyl methacrylate, 20% ethylene glycol dimethacrylate and 60% porogens (36% 1-propanol, 18% 1,4-butanediol) or 16.4% monomers (16% butyl methacrylate
Chenchen Guo et al.
Pharmaceutical research, 31(11), 3051-3059 (2014-05-09)
The acne skin is characteristic of a relatively lower pH microenvironment compared to the healthy skin. The aim of this work was to utilize such pH discrepancy as a site-specific trigger for on-demand topical adapalene delivery. The anti-acne agent, adapalene
Marwa Ahmed et al.
Chirality, 26(11), 754-763 (2014-03-08)
New affinity monolithic capillary columns of 150 µm internal diameter were prepared in situ fused glass capillary via either immobilization or encapsulation of Candida antarctica lipase B (CALB) on or within polymer monoliths, respectively. The immobilized lipase-based monoliths were prepared
Rui Yang et al.
Analytical and bioanalytical chemistry, 407(3), 737-747 (2014-07-12)
Microfluidic systems with monolithic columns have been developed for preconcentration and on-chip labeling of model proteins. Monoliths were prepared in microchannels by photopolymerization, and their properties were optimized by varying the composition and concentration of the monomers to improve flow
Íris Duarte et al.
Pharmaceutical research, 32(1), 222-237 (2014-08-20)
To present a new screening methodology intended to be used in the early development of spray-dried amorphous solid dispersions. A model that combines thermodynamic, kinetic and manufacturing considerations was implemented to obtain estimates of the miscibility and phase behavior of
Kateřina Punčochová et al.
International journal of pharmaceutics, 469(1), 159-167 (2014-04-23)
The objective of this study was to investigate the effect of different polymeric carriers in solid dispersions with an active pharmaceutical ingredient (API) on their water vapour sorption equilibria and the influence of the API-polymer interactions on the dissolution rate
Silke Schlaubitz et al.
PloS one, 9(10), e110251-e110251 (2014-10-21)
The repair of bone defects is of particular interest for orthopedic, oral, maxillofacial, and dental surgery. Bone loss requiring reconstruction is conventionally addressed through bone grafting. Depending on the size and the location of the defect, this method has limits
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