Merck
CN

CACNA1F

calcium channel, voltage-dependent, L type, alpha 1F subunit

别名:
AIED, COD3, COD4, CORDX, CORDX3, CSNB2, CSNB2A, CSNBX2, Cav1.4, Cav1.4alpha1, JM8, JMC8, OA2
物种:
UniProtKB ID:
基因ID:
  • Human(778) Summary: This gene encodes a member of the alpha-1 subunit family; a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been shown to cause incomplete X-linked congential stationary night blindness type 2 (CSNB2). [provided by RefSeq, Feb 2012]
  • Mouse(54652) calcium channel, voltage-dependent, alpha 1F subunit
  • Rat(114493) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • sheep(101104552) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • naked mole-rat(101722090) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • domestic guinea pig(100720484) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • Zebrafish(386662) calcium channel, voltage-dependent, alpha 1F subunit
  • domestic cat(101080870) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • dog(480915) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • cow(509779) calcium channel, voltage-dependent, L type, alpha 1F subunit

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Small Molecule - Allosteric Modulator

货号
说明
物种
加巴喷丁, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
普瑞巴林, European Pharmacopoeia (EP) Reference Standard,
物种
human
加巴喷丁标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
加巴喷丁, European Pharmacopoeia (EP) Reference Standard,
物种
human
加巴喷丁, United States Pharmacopeia (USP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-CACNA1F antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry

Small Molecule - Blocker

货号
说明
物种
苯磺酸氨氯地平, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
(±)-维拉帕米 盐酸盐, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
维拉帕米 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
苯磺酸氨氯地平, ≥98% (HPLC),
物种
human
硝苯地平, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CACNA1F,
物种
human