Merck
CN

GRIK2

glutamate receptor, ionotropic, kainate 2

别名:
EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6
物种:
UniProtKB ID:
基因ID:
  • Human(2898) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008]
  • Mouse(14806) glutamate receptor, ionotropic, kainate 2 (beta 2)
  • Rat(54257) glutamate receptor, ionotropic, kainate 2
  • chicken(428628) glutamate receptor, ionotropic, kainate 2
  • dog(481938) glutamate receptor, ionotropic, kainate 2
  • Thale Cress(836176) geminivirus rep interacting kinase 2
  • Zebrafish(556013) glutamate receptor, ionotropic, kainate 2
  • cow(615226) glutamate receptor, ionotropic, kainate 2
  • naked mole-rat(101697577) glutamate receptor, ionotropic, kainate 2
  • domestic guinea pig(100733104) glutamate receptor, ionotropic, kainate 2
  • sheep(101122701) glutamate receptor, ionotropic, kainate 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

货号
说明
物种
L-谷氨酸 盐酸盐, ≥99% (HPLC),
物种
human
(±)-AMPA, solid,
物种
rat
红藻氨酸 一水合物, ≥99% (TLC),
物种
human, mouse, rat
(S)-AMPA, ≥98%,
物种
mouse, human, rat
氨甲基膦酸, 99%,
物种
rat, human

Small Molecule - Antagonist

货号
说明
物种
CNQX, ≥98% (HPLC), solid,
物种
rat
NBQX 二钠盐 水合物, ≥98% (HPLC),
物种
human
DNQX, ≥98% (TLC),
物种
mouse, rat, human
(±)-AMPA, solid,
物种
rat
红藻氨酸 一水合物, ≥99% (TLC),
物种
human, mouse, rat

Antibodies

货号
说明
物种反应性
应用
抗-GluR6/7抗体,克隆NL9,兔单克隆, culture supernatant, clone NL904, Upstate®,
物种反应性
human, mouse, rat
应用
immunoprecipitation (IP)
western blot
Anti-GRIK2 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot
Anti-GRIK2 Antibody, clone 4B4L9, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
immunohistochemistry
western blot
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-GRIK2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
(±)-AMPA, solid,
物种
rat
红藻氨酸 一水合物, ≥99% (TLC),
物种
human, mouse, rat
L-谷氨酸, ReagentPlus®, ≥99% (HPLC),
物种
rat, human
L-谷氨酸, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
物种
rat, human
L-谷氨酸, BioUltra, ≥99.5% (NT),
物种
rat, human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GRIK2 (1),
物种
human
MISSION® esiRNA, targeting human GRIK2 (2),
物种
human