Merck
CN
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文件

06-315

Sigma-Aldrich

Anti-KA2/GRIK5 (Kainate Receptor) Antibody

Upstate®, from rabbit

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别名:
Anti-EAA2, Anti-GRIK2, Anti-GluK5, Anti-KA2
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

100

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

polyclonal

种属反应性

rat, rabbit

制造商/商品名称

Upstate®

技术

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同位素/亚型

IgG

NCBI登记号

NM_017262
NM_031508

UniProt登记号

Q16478

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

human ... GRIK5(2901)

特异性

KA2

免疫原

21 residue synthetic peptide (KTSPPRPRPGPTGPRELTEHE) corresponding to the c-terminus of rat KA2 with a lysine added to the n-terminus

应用

Anti-KA2/GRIK5 (Kainate Receptor) Antibody is an antibody against KA2/GRIK5 (Kainate Receptor) for use in IC, IH, IP & WB.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins

Neurodegenerative Diseases

质量

routinely evaluated by immunoblot on rat brain microsomal preparation

目标描述

123kDa

外形

Protein G Chromatography
Format: Purified
of 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%

储存及稳定性

2 years at -20°C

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Role of NMDA and non-NMDA ionotropic glutamate receptors in traumatic spinal cord axonal injury
Agrawal, S. K. and Fehlings, M. G.
The Journal of Neuroscience, 17, 1055-1063 (1997)
Synaptic expression of the high-affinity kainate receptor subunit KA2 in hippocampal cultures
Roche, K. W. and Huganir, R. L.
Neuroscience, 69, 383-393 (1995)
A Herb et al.
Neuron, 8(4), 775-785 (1992-04-01)
A new ionotropic glutamate receptor subunit termed KA-2, cloned from rat brain cDNA, exhibits high affinity for [3H]kainate (KD approximately 15 nM). KA-2 mRNA is widely expressed in embryonic and adult brain. Homomeric KA-2 expression does not generate agonist-sensitive channels
Sanja Selak et al.
Neuron, 63(3), 357-371 (2009-08-15)
Regulation of surface insertion and internalization of AMPA and NMDA receptors has emerged as a key mechanism for the control of synaptic strength. Regulatory elements for synaptic kainate receptors (KARs) are, however, largely undetermined. We have found that SNAP25 is
E P Garcia et al.
Neuron, 21(4), 727-739 (1998-11-10)
The mechanism of kainate receptor targeting and clustering is still unresolved. Here, we demonstrate that members of the SAP90/PSD-95 family colocalize and associate with kainate receptors. SAP90 and SAP102 coimmunoprecipitate with both KA2 and GluR6, but only SAP97 coimmunoprecipitates with
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