Merck
CN

HTR1A

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

别名:
5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD
物种:
UniProtKB ID:
基因ID:
  • Human(3350) Summary: This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
  • Mouse(15550) 5-hydroxytryptamine (serotonin) receptor 1A
  • Rat(24473) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • chicken(431581) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • naked mole-rat(101718872) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • dog(487230) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic guinea pig(100301563) 5-hydroxytryptamine (serotonin) receptor 1A
  • cow(407137) 5-hydroxytryptamine (serotonin) receptor 1A
  • Horse(100009683) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic cat(101101542) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • Domestic Rabbit(100008780) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • sheep(101105852) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

货号
说明
物种
Xaliproden, ≥97% (HPLC), solid,
物种
human
丁螺环酮盐酸盐 盐酸盐, ,
物种
human
盐酸丁螺环酮, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
丁螺环酮盐酸盐 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
丁螺环酮盐酸盐 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
DCEBIO, ≥98% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
WAY-100635 马来酸盐, powder,
物种
human
GR 103691, ≥98% (HPLC), solid,
物种
rat
1-(3-甲氧基苯基)哌嗪, 95%,
物种
rat
BMY 7378 dihydrochloride, ≥98% (HPLC), solid,
物种
human
枸橼酸阿尔维林 柠檬酸盐, British Pharmacopoeia (BP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
抗-血清素 兔抗, whole antiserum,
物种反应性
human, rat
应用
immunohistochemistry
Anti-Serotonin Receptor 1A Antibody, serum, Chemicon®,
物种反应性
rat
应用
immunohistochemistry
Anti-Htr1a antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
western blot
抗-5-羟色胺抗体,克隆YC5/45, culture supernatant, clone YC5/45, Chemicon®,
物种反应性
human, lizard, mouse, pig, rabbit, rat
应用
immunohistochemistry
Anti-5-HT-1A antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot

Small Molecule - Blocker

货号
说明
物种
曲唑酮 盐酸盐, ≥99% (HPLC), powder,
物种
human
三甲丙咪嗪标准液 马来酸盐, ≥98% (TLC), powder,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
维拉佐酮 盐酸盐 溶液, 1 mg/mL (Methanol:DMSO (90:10) (v/v)), certified reference material, ampule of 1 mL, Cerilliant®,
物种
human
维拉佐酮 盐酸盐, ≥98% (HPLC),
物种
human
1,2,3,4-四氢异喹啉, 95%,
物种
rat, human
曲唑酮 盐酸盐, ≥99% (HPLC), powder,
物种
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
物种
human

Small Molecule - Ligand

货号
说明
物种
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
物种
human

Small Molecule - Metabolite

货号
说明
物种
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,
物种
human

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
BP897, >98% (HPLC), solid,
物种
human, rat
米非司酮, ≥98%,
物种
human, mouse, rat
氟哌啶醇, powder,
物种
human, rat
氯氮平标准液, ,
物种
human, rat

Small Molecule - Precursor

货号
说明
物种
5-羟基L-色氨酸, powder,
物种
human

Proteins

货号
说明
物种
Serotonin Receptor 1A, Control Peptide for AB5406, ,
物种
rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human HTR1A,
物种
human