CN
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
别名:
AEMK, EA1, HBK1, HUK1, KV1.1, MBK1, MK1, RBK1
物种:
Human KCNA1 (3736), Mouse Kcna1 (16485), Rat Kcna1 (24520), cow KCNA1 (538703), domestic cat KCNA1 (101093364), Horse KCNA1 (100051648), dog KCNA1 (486732), Zebrafish kcna1 (327087), chicken KCNA1 (428101), domestic guinea pig Kcna1 (100731979) ...展开
UniProtKB ID:
基因ID:
- Human(3736) Summary: This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq, Jul 2008]
- Mouse(16485) potassium voltage-gated channel, shaker-related subfamily, member 1
- Rat(24520) potassium voltage-gated channel, shaker-related subfamily, member 1
- cow(538703) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- domestic cat(101093364) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- Horse(100051648) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- dog(486732) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- Zebrafish(327087) potassium voltage-gated channel, shaker-related subfamily, member 1
- chicken(428101) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- domestic guinea pig(100731979) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- Domestic Rabbit(100037722) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- Domestic Rabbit(100037717) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
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Antibodies
货号
说明
物种反应性
应用
Anti-Potassium Channel Kv1.1 Antibody, clone K36/15, clone K36/15, from mouse,
物种反应性
mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Potassium Channel Kv1.1 Antibody, Chemicon®, from rabbit,
物种反应性
mouse, rat
应用
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-KCNA1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
western blot
Anti-KCNA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-KCNA1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot