CN
PRKCG
protein kinase C, gamma
别名:
PKC-gamma, PKCC, PKCG, SCA14
物种:
Human PRKCG (5582), Mouse Prkcg (18752), Rat Prkcg (24681), cow PRKCG (282002), Horse PRKCG (100062549), sheep PRKCG (101116423), naked mole-rat Prkcg (101698346), Domestic Rabbit PRKCG (100009102), domestic cat PRKCG (101082196), dog PRKCG (484316) ...展开
UniProtKB ID:
基因ID:
- Human(5582) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq, Jul 2008]
- Mouse(18752) protein kinase C, gamma
- Rat(24681) protein kinase C, gamma
- cow(282002) protein kinase C, gamma
- Horse(100062549) protein kinase C, gamma
- sheep(101116423) protein kinase C, gamma
- naked mole-rat(101698346) protein kinase C, gamma
- Domestic Rabbit(100009102) protein kinase C, gamma
- domestic cat(101082196) protein kinase C, gamma
- dog(484316) protein kinase C, gamma
- domestic guinea pig(100733947) protein kinase C, gamma
- Zebrafish(100003514) protein kinase C, gamma
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Small Molecule - Agonist
货号
说明
物种
Antibodies
货号
说明
物种反应性
应用
Anti-p-PKCγ (Thr514) Antibody, clone 4F20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
immunohistochemistry
inhibition assay
western blot
inhibition assay
western blot
Anti-PKCγ Antibody, clone 2B9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, rat
应用
affinity binding assay
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-PRKCG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-PRKCG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Small Molecule - Inhibitor
Proteins
货号
说明
物种
PKCγ, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
esiRNA
货号
说明
物种