Merck
CN

SCN11A

sodium channel, voltage-gated, type XI, alpha subunit

别名:
NAV1.9, NaN, SCN12A, SNS-2
物种:
UniProtKB ID:
基因ID:
  • Human(11280) Summary: Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.[supplied by OMIM, Apr 2004]
  • Mouse(24046) sodium channel, voltage-gated, type XI, alpha
  • Rat(29701) sodium channel, voltage-gated, type XI, alpha subunit
  • domestic guinea pig(100734219) sodium channel, voltage-gated, type XI, alpha subunit
  • Domestic Rabbit(100349709) sodium channel, voltage-gated, type XI, alpha subunit
  • sheep(101117022) sodium channel, voltage-gated, type XI, alpha subunit
  • cow(535956) sodium channel, voltage-gated, type XI, alpha subunit
  • domestic cat(101085312) sodium channel, voltage-gated, type XI, alpha subunit
  • dog(485593) sodium channel, voltage-gated, type XI, alpha subunit
  • naked mole-rat(101723747) sodium channel, voltage-gated, type XI, alpha subunit

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Antibodies

货号
说明
物种反应性
应用
Anti-SCN11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-SCN11A, (C-terminal) antibody produced in mouse, clone 2B10, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-SCN11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
抗-钠离子通道 NaV1.9 兔抗, affinity isolated antibody, lyophilized powder,
物种反应性
rat
应用
western blot
Pan单克隆抗 钠通道 小鼠抗, ~1 mg/mL, clone K58/35, purified immunoglobulin,
物种反应性
mammals
应用
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

货号
说明
物种
拉莫三嗪, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
苯妥英钠, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
卡马西平标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
2,4-二氯苯甲醇, 99%,
物种
human
苯妥英标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human

Small Molecule - Ligand

货号
说明
物种
拉莫三嗪, ≥98%, powder,
物种
rat, human

Proteins

货号
说明
物种
PrEST Antigen SCN11A, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
物种
human
PrEST Antigen SCN11A, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human SCN11A,
物种
human