Merck
CN

SCN7A

sodium channel, voltage-gated, type VII, alpha subunit

别名:
NaG, Nav2.1, Nav2.2, SCN6A
物种:
UniProtKB ID:
基因ID:
  • Human(6332) Summary: This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011]
  • Mouse(20272) sodium channel, voltage-gated, type VII, alpha
  • Rat(64155) sodium channel, voltage-gated, type VII, alpha
  • naked mole-rat(101711842) sodium channel, voltage-gated, type VII, alpha subunit
  • domestic guinea pig(100715553) sodium channel, voltage-gated, type VII, alpha subunit
  • dog(488382) sodium channel, voltage-gated, type VII, alpha subunit
  • Horse(100062186) sodium channel, voltage-gated, type VII, alpha subunit
  • cow(507516) sodium channel, voltage-gated, type VII, alpha subunit
  • sheep(101109522) sodium channel, voltage-gated, type VII, alpha subunit
  • domestic cat(101082080) sodium channel, voltage-gated, type VII, alpha subunit

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Antibodies

货号
说明
物种反应性
应用
Anti-SCN7A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-SCN7A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

Small Molecule - Blocker

货号
说明
物种
拉莫三嗪, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
苯妥英钠, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
卡马西平标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
2,4-二氯苯甲醇, 99%,
物种
human
苯妥英标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human

Proteins

货号
说明
物种
PrEST Antigen SCN7A, Prestige Antibodies® Powered by Atlas Antibodies, buffered aqueous solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Scn7a,
物种
mouse